David Lawrence

Prof. David Lawrence


Research Focus & Metrics

Academic Career Length

28Years (1999-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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21 May 2013 in BMJ
Verified
Journal Article
Open access
PDF file
DLDavid Lawrence
David Lawrence
KHKirsten J Hancock
Kirsten J Hancock
SKStephen Kisely
Stephen Kisely
Objective To examine the mortality experience of psychiatric patients in Western Australia compared with the general population. Design Population based study. Setting Western Australia, 1985-2005. Participants Psychiatric patients (292 585) registered with mental health services in Western Australia. Main outcome measures Trends in life expectancy for psychiatric patients compared with the Western Australian population and causes of excess mortality, including physical health conditions and unnatural causes of death. Results When using active prevalence of disorder (contact with services in previous five years), the life expectancy gap increased from 13.5 to 15.9 years for males and from 10.4 to 12.0 years for females between 1985 and 2005. Additionally, 77.7% of excess deaths were attributed to physical health conditions, including cardiovascular disease (29.9%) and cancer (13.5%). Suicide was the cause of 13.9% of excess deaths. Conclusions Despite knowledge about excess mortality in people with mental illness, the gap in their life expectancy compared with the general population has widened since 1985. With most excess deaths being due to physical health conditions, public efforts should be directed towards improving physical health to reduce mortality in people with mental illness, in addition to ongoing efforts to prevent suicide.

5 October 2010 in Journal of Psychopharmacology
Verified
Journal Article
Open access
DLDavid Lawrence
David Lawrence
SKStephen Kisely
Stephen Kisely
There are many factors that contribute to the poor physical health of people with severe mental illness (SMI), including lifestyle factors and medication side effects. However, there is increasing evidence that disparities in healthcare provision contribute to poor physical health outcomes. These inequalities have been attributed to a combination of factors including systemic issues, such as the separation of mental health services from other medical services, healthcare provider issues including the pervasive stigma associated with mental illness, and consequences of mental illness and side effects of its treatment. A number of solutions have been proposed. To tackle systemic barriers to healthcare provision integrated care models could be employed including co-location of physical and mental health services or the use of case managers or other staff to undertake a co-ordination or liaison role between services. The health care sector could be targeted for programmes aimed at reducing the stigma of mental illness. The cognitive deficits and other consequences of SMI could be addressed through the provision of healthcare skills training to people with SMI or by the use of peer supporters. Population health and health promotion approaches could be developed and targeted at this population, by integrating health promotion activities across domains of interest. To date there have only been small-scale trials to evaluate these ideas suggesting that a range of models may have benefit. More work is needed to build the evidence base in this area.

7 August 2009 in BMC Public Health
Verified
Journal Article
Open access
PDF file
DLDavid Lawrence
David Lawrence
FMFrancis Mitrou
Francis Mitrou
SZStephen R Zubrick
Stephen R Zubrick
Smoking has been associated with a range of mental disorders including schizophrenia, anxiety disorders and depression. People with mental illness have high rates of morbidity and mortality from smoking related illnesses such as cardiovascular disease, respiratory diseases and cancer. As many people who meet diagnostic criteria for mental disorders do not seek treatment for these conditions, we sought to investigate the relationship between mental illness and smoking in recent population-wide surveys.

1 February 2013 in JAMA Psychiatry
Verified
Journal Article
Open access
PDF file
SKStephen Kisely
Stephen Kisely
ECElizabeth Crowe
Elizabeth Crowe
DLDavid Lawrence
David Lawrence
Mortality rates in psychiatric patients are much greater than in the general population,1-17 including Nordic countries where longstanding egalitarian health and welfare policies might be expected to facilitate treatment access.1,6,8,9,13 Chronic physical disorders such as cardiovascular disease and cancer are the main cause,8,10-12 accounting for 10 times the absolute numbers of suicide in one study but receiving far less attention.11,18 In cancer, overall mortality is higher in psychiatric patients, even though the incidence is similar to that in the general population.10,14,15,17 The disparity between incidence and mortality is most marked for several common sites such as prostate and colorectal cancers. Possible explanations might be delayed diagnosis or lack of access to screening, leading to more advanced staging at diagnosis, and reduced access to or use of appropriate treatments after diagnosis.

20 July 2016 in Australian & New Zealand Journal of Psychiatry
Verified
Journal Article
Closed access
DLDavid Lawrence
David Lawrence
JHJennifer Hafekost
Jennifer Hafekost
SJSarah E Johnson
Sarah E Johnson
SSSuzy Saw
Suzy Saw
WBWilliam J Buckingham
William J Buckingham
SZStephen R Zubrick
Stephen R Zubrick
Objective: To estimate the prevalence of mental disorders in children and adolescents in Australia, and the severity and impact of those mental disorders. Method: Seven mental disorders were assessed using the parent- or carer-completed version of the Diagnostic Interview Schedule for Children Version IV, and major depressive disorder was also assessed using the youth self-report version of the Diagnostic Interview Schedule for Children Version IV. Severity and impact were assessed using an extended version of the Diagnostic Interview Schedule for Children Version IV impact on functioning questions, and days absent from school due to symptoms of mental disorders. Data were collected in a national face-to-face survey of 6310 parents or carers of children and adolescents aged 4–17 years, with 2969 young people aged 11–17 years also completing a self-report questionnaire. Results: Twelve-month prevalence of mental disorders was 13.9%, with 2.1% of children and adolescents having severe disorders, 3.5% having moderate disorders and 8.3% having mild disorders. The most common class of disorders was attention-deficit/hyperactivity disorder followed by anxiety disorders. Mental disorders were more common in step-, blended- or one-parent families, in families living in rented accommodation and families where one or both carers were not in employment. Mental disorders were associated with a substantial number of days absent from school particularly in adolescents. Conclusion: Mental disorders are common in children and adolescents, often have significant impact and are associated with substantial absences from school. Child and adolescent mental disorders remain an important public health problem in Australia. Accurate information about prevalence and severity of child and adolescent mental disorders is an essential prerequisite for effective mental health policy and service planning.

2 January 2003 in The British Journal of Psychiatry
Verified
Journal Article
Closed access
PDF file
DLDavid Lawrence
David Lawrence
CDCashel D'Arcy
Cashel D'Arcy
JHJ. Holman
J. Holman
AJAssen V. Jablensky
Assen V. Jablensky
MHMichael S. T. Hobbs
Michael S. T. Hobbs
Background People with mental illness suffer excess mortality due to physical illnesses.