This paper focuses on the use of local Explainable Artificial Intelligence (XAI) methods, particularly the Local Rule-Based Explanations (LORE) technique, within healthcare and medical settings. It emphasizes the critical role of interpretability and transparency in AI systems for diagnosing diseases, predicting patient outcomes, and creating personalized treatment plans. While acknowledging the complexities and inherent trade-offs between interpretability and model performance, our work underscores the significance of local XAI methods in enhancing decision-making processes in healthcare. By providing granular, case-specific insights, local XAI methods like LORE enhance physicians’ and patients’ understanding of machine learning models and their outcome. Our paper reviews significant contributions to local XAI in healthcare, highlighting its potential to improve clinical decision making, ensure fairness, and comply with regulatory standards.

Human mobility data are an important proxy to understand human mobility dynamics, develop analytical services, and design mathematical models for simulation and what-if analysis. Unfortunately mobility data are very sensitive since they may enable the re-identification of individuals in a database. Existing frameworks for privacy risk assessment provide data providers with tools to control and mitigate privacy risks, but they suffer two main shortcomings: (i) they have a high computational complexity; (ii) the privacy risk must be recomputed every time new data records become available and for every selection of individuals, geographic areas, or time windows. In this article, we propose a fast and flexible approach to estimate privacy risk in human mobility data. The idea is to train classifiers to capture the relation between individual mobility patterns and the level of privacy risk of individuals. We show the effectiveness of our approach by an extensive experiment on real-world GPS data in two urban areas and investigate the relations between human mobility patterns and the privacy risk of individuals.

Privacy risk assessment is a crucial issue in any privacy-aware analysis process. Traditional frameworks for privacy risk assessment systematically generate the assumed knowledge for a potential adversary, evaluating the risk without realistically modelling the collection of the background knowledge used by the adversary when performing the attack. In this work, we propose Simulated Privacy Annealing (SPA), a new adversarial behavior model for privacy risk assessment in mobility data. We model the behavior of an adversary as a mobility trajectory and introduce an optimization approach to find the most effective adversary trajectory in terms of privacy risk produced for the individuals represented in a mobility data set. We use simulated annealing to optimize the movement of the adversary and simulate a possible attack on mobility data. We finally test the effectiveness of our approach on real human mobility data, showing that it can simulate the knowledge gathering process for an adversary in a more realistic way.