Manikandan Gurusamy

Dr. Manikandan Gurusamy

Department of Pharmaceutical Sciences, Tshwane University of Technology, Pretoria, Gauteng, South Africa
orcid

Research Focus & Metrics

Academic Career Length

12Years (2015-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 November 2023 in Clinical Complementary Medicine and Pharmacology
Verified
Journal Article
Open access
SRSumathy Raj
Sumathy Raj
MRMonica Shree Gnana Soundara Rajan
Monica Shree Gnana Soundara Rajan
SRSuganthi Ramasamy
Suganthi Ramasamy
Rimal IsaacRimal Isaac
Rimal Isaac
RARamathilaga Ariyamuthu
Ramathilaga Ariyamuthu
Manikandan GurusamyManikandan Gurusamy
Manikandan Gurusamy

23 October 2017 in INTERNATIONAL RESEARCH JOURNAL OF PHARMACY
Verified
Journal Article
Closed access
Manikandan GurusamyManikandan Gurusamy
Manikandan Gurusamy
VAVimala Rani A
Vimala Rani A
DCDivya C
Divya C
RRRamasubbu R
Ramasubbu R

8 February 2025 in Plants
Verified
Journal Article
Open access
PDF file
FDFelix Irudhyaraj Dhanaraj
Felix Irudhyaraj Dhanaraj
Jagadheeshkumar KalimuthuJagadheeshkumar Kalimuthu
Jagadheeshkumar Kalimuthu
PBPavan Santhosh Balamurugan
Pavan Santhosh Balamurugan
PSPunitha Subramani
Punitha Subramani
DKDavid Katerere
David Katerere
Manikandan GurusamyManikandan Gurusamy
Manikandan Gurusamy
Numerous bioactive chemicals with a range of advantageous effects on human metabolism can be found in medicinal plants. The knowledge of these phytochemicals is essential for the identification of potential medicines. In the present study, Sesamum prostratum was selected for GC-MS profiling and antioxidant studies. Plant extracts were prepared with ethanol, ethyl acetate, and acetone by using the continuous hot Soxhlet extraction method. The chemical compositions were analyzed by GC/MS. In addition, antioxidant activity was measured using ABTS, DPPH, and hydrogen peroxide assay. The GC-MS analysis of the different solvent extracts showed a total of 32 compounds present in S. prostratum. Ethanol extracts showed 11 compounds, ethyl acetate extracts showed 8 compounds, and acetone extracts showed the presence of 13 compounds. Different dominant chemicals were identified in each solvent extract by the phytochemical study. The chemical composition of the extracts revealed notable differences. The ethanol extract was dominated by 1,2-benzenedicarboxylic acid, which comprised 51.4% of the total composition. In contrast, the acetone extract had 3-ethyl-4-methylhexane as its primary component, while the ethyl acetate extract was characterized by the presence of 1,2-benzenedicarboxylic acid as its major chemical constituent. The different assay on free radical scavenging activity of the extracts showed antioxidant activity. The acetone extracts showed the least IC50 value of 35.13 μg/mL for the hydrogen peroxide test, the ethyl acetate showed IC50 value 65.49 μg/mL in the ABTS assay, and the ethanol extract showed the lowest IC50 value of 80.84 μg/mL in the DPPH assay. The results indicated that the plant has bioactive compounds with antioxidant potential that can be further investigated for anticancer and other medicinal uses.

31 January 2019 in INTERNATIONAL RESEARCH JOURNAL OF PHARMACY
Verified
Journal Article
Closed access
Manikandan GurusamyManikandan Gurusamy
Manikandan Gurusamy
PPPandiselvi P
Pandiselvi P
SNSobana N
Sobana N
MMMurugan M
Murugan M

23 March 2015 in Phytotaxa
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Journal Article
Closed access
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RRRaju Ramasubbu
Raju Ramasubbu
Manikandan GurusamyManikandan Gurusamy
Manikandan Gurusamy
MPMehalingam P
Mehalingam P
PAPandurangan Ag
Pandurangan Ag
Impatiens courtallensis, a new species from Tamil Nadu, India is newly described and illustrated. This species is characterized by having typical opposite deccusate leaves, minute flower (≤4mm across), milky white, boat shaped lower sepal with outwardly curved tip, minute spur, seeds with prominent caruncle and typical squarish pollengrains. This combination of characters makes determining the relationships of I. courtallensis difficult.

1 January 2024 in International Journal of Pharmaceutical Research and Allied Sciences
Verified
Journal Article
Open access
PDF file
RMRanjithkumar Murugesan
Ranjithkumar Murugesan
DSDavid Noel Stephen
David Noel Stephen
TVTamizhazhagan Vairakannu
Tamizhazhagan Vairakannu
Manikandan GurusamyManikandan Gurusamy
Manikandan Gurusamy
SGSattanathan Govindharajan
Sattanathan Govindharajan
An ethnobotanical study was carried out among Mannan, Urali, and Paliyan communities at Kozhimala and Chakkupallom villages of Idukki dist, Kerela. Information on one hundred plants used by them as a source of medicine for various ailments was collected through a questionnaire. Totally 68 plant species were collected from the Mannan community, 16 from the Urali, and another 16 from Paliyan community. The plant parts used as sources of medicine by targeted tribes were, leaves (52%), followed by r