Background: Studying comorbidities of disorders is important for detection and prevention. For discovering frequent patterns of diseases we can use retrospective analysis of population data, by filtering events with common properties and similar significance. Most frequent pattern mining methods do not consider contextual information about extracted patterns. Further data mining developments might enable more efficient applications in specific tasks like comorbidities identification.Methods: We propose a cascade data mining approach for frequent pattern mining enriched with context information, including a new algorithm MIxCO for maximal frequent patterns mining. Text mining tools extract entities from free text and deliver additional context attributes beyond the structured information about the patients.Results: The proposed approach was tested using pseudonymised reimbursement requests (outpatient records) submitted to the Bulgarian National Health Insurance Fund in 2010–2016 for more than 5 million citizens yearly. Experiments were run on 3 data collections. Some known comorbidities of Schizophrenia, Hyperprolactinemia and Diabetes Mellitus Type 2 are confirmed; novel hypotheses about stable comorbidities are generated. The evaluation shows that MIxCO is efficient for big dense datasets.Conclusion: Explicating maximal frequent itemsets enables to build hypotheses concerning the relationships between the exogeneous and endogeneous factors triggering the formation of these sets. MixCO will help to identify risk groups of patients with a predisposition to develop socially-significant disorders like diabetes. This will turn static archives like the Diabetes Register in Bulgaria to a powerful alerting and predictive framework.

This paper presents the results of an on-going research project for knowledge extraction from large corpora of clinical narratives in Bulgarian language, approximately 100 million of outpatient care notes. Entities with numerical values are mined in the free text and the extracted information is stored in a structured format. The Algorithms for retrospective analyses and big data analytics are applied for studying the treatment and evaluating the diabetes compensation and control of arterial blood pressure.

Digital Libraries (DL) are offering access to a vast amount of digital\ud content, relevant to practically all domains of human knowledge, which makes it\ud suitable to enhance teaching and learning. Based on a systematic literature review,\ud this article provides an overview and a gap analysis of educational use of DLs.The research work presented in this paper is partially supported by the FP7 Grant\ud 316087 AComIn ”Advanced Computing for Innovation”, funded by the European Commission in the FP7 Capacity Programme in 2012-2016.peer-reviewe

Sublanguages are varieties of language that form “subsets” of the general language, typically exhibiting particular types of lexical, semantic, and other restrictions and deviance. SubCAT, the Sublanguage Corpus Analysis Toolkit, assesses the representativeness and closure properties of corpora to analyze the extent to which they are either sublanguages, or representative samples of the general language. The current version of SubCAT contains scripts and applications for assessing lexical closure, morphological closure, sentence type closure, over-represented words, and syntactic deviance. Its operation is illustrated with three case studies concerning scientific journal articles, patents, and clinical records. Materials from two language families are analyzed—English (Germanic), and Bulgarian (Slavic). The software is available at sublanguage.sourceforge.net under a liberal Open Source license.