Since the novel coronavirus (COVID-19) outbreak in China, and due to the open accessibility of COVID-19 data, several researchers and modellers revisited the classical epidemiological models to evaluate their practical applicability. While mathematical compartmental models can predict various contagious viruses’ dynamics, their efficiency depends on the model parameters. Recently, several parameter estimation methods have been proposed for different models. In this study, we evaluated the Ensemble Kalman filter’s performance (EnKF) in the estimation of time-varying model parameters with synthetic data and the real COVID-19 data of Hubei province, China. Contrary to the previous works, in the current study, the effect of damping factors on an augmented EnKF is studied. An augmented EnKF algorithm is provided, and we present how the filter performs in estimating models using uncertain observational (reported) data. Results obtained confirm that the augumented-EnKF approach can provide reliable model parameter estimates. Additionally, there was a good fit of profiles between model simulation and the reported COVID-19 data confirming the possibility of using the augmented-EnKF approach for reliable model parameter estimation.
21 September 2016 in International Journal for Numerical Methods in Biomedical Engineering
Using the data provided by Fiji's ministry of health and medical services, we apply an implicit time-discrete SIR (susceptible people–infectious people–removed people) model that tracks the transmission and recovering rate at time, t to predict the trend of the coronavirus disease 2019 (COVID-19) pandemic in Fiji. The model implied time-varying transmission and recovery rates were calculated from 4 May 2021 to 9 October 2021. The estimator functions for these rates were determined, and a short-term (30 days) forecast was done. The model was validated with observed values of the active and recovered cases from 11 October 2021 to 9 December 2021. Statistical results reveal a good fit of profiles between model simulated and the reported COVID-19 data. The gradual decrease of the time-varying basic reproduction number with values below one towards the end of the study period suggest the government's success in controlling the epidemic. The mean reproduction number for the second wave of COVID-19 in Fiji was estimated as 2.7818. The results from this study can be used by researchers, the Fijian government, and the relevant health policy makers in making informed decisions should a third COVID-19 wave occur.
24 December 2014 in Journal of Mathematical Chemistry
This study involves the estimation of a key epidemiological parameter for evaluating and monitoring the transmissibility of a disease. The time-varying reproduction number is the index for quantifying the transmissibility of infectious diseases. Accurate and timely estimation of the time-varying reproduction number is essential for optimizing non-pharmacological interventions and movement control orders during epidemics. The time-varying reproduction number for the second wave of the pandemic in Fiji is estimated using the popular EpiEstim R package and the publicly available COVID-19 data from 19 April 2021 to 1 December 2021. Our findings show that the non-pharmacological interventions and movement control orders introduced and enforced by the Fijian Government had a significant impact in preventing the spread of COVID-19. Moreover, the results show that many restrictions were either relaxed or eased when the time-varying reproduction number was below the threshold value of 1. The results have provided some information on the second wave of the COVID-19 pandemic that could be used in the future as a guide for public health policymakers in Fiji. Estimation of time-varying reproduction numbers would be helpful for continuous monitoring of the effectiveness of the current public health policies that are being implemented in Fiji.