Ana Sá-Sousa

Prof. Dr. Ana Sá-Sousa

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Research Focus & Metrics

Academic Career Length

17Years (2010-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 July 2010 in Allergy
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Journal Article
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JFJoao A. da Fonseca
Joao A. da Fonseca
LNL. Nogueira‐Silva
L. Nogueira‐Silva
MMM. Morais‐Almeida
M. Morais‐Almeida
LALuís Azevedo
Luís Azevedo
ASAna Sá-Sousa
Ana Sá-Sousa
JBJ. Bousquet
J. Bousquet

13 October 2010 in Journal of Cellular Physiology
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MCMaria Adelina Coelho Ribeiro Costa
Maria Adelina Coelho Ribeiro Costa
ABA. Barbosa
A. Barbosa
ENEstrela Neto
Estrela Neto
ASAna Sá-Sousa
Ana Sá-Sousa
RFR. Freitas
R. Freitas
Paulo Correia-de-SáPaulo Correia-de-Sá
Paulo Correia-de-Sá

1 January 2012 in Clinical and Translational Allergy
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Journal Article
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ASAna Sá-Sousa
Ana Sá-Sousa
MMMário Morais‐Almeida
Mário Morais‐Almeida
LALuís Azevedo
Luís Azevedo
RCRosa Carvalho
Rosa Carvalho
TJTiago Jacinto
Tiago Jacinto
JFJoao A. da Fonseca
Joao A. da Fonseca
Background: Asthma is a frequent chronic respiratory disease in both children and adults. However, few data on asthma prevalence are available in Portugal. The Portuguese National Asthma Survey is the first nationwide study that uses standardized methods. We aimed to estimate the prevalence of current asthma in the Portuguese population and to assess the association between ‘Current asthma’ and comorbidities such as upper airways disease.Methods: A cross‐sectional, population‐based, telephone interview survey including all municipalities of Portugal was undertaken. Participants were randomly selected to answer a questionnaire based on the Portuguese version of the GA2LEN survey. ‘Current asthma’ was defined as self‐reported lifetime asthma and at least one of 3 symptoms in the last 12 months: wheezing, waking with breathlessness or having an asthma attack.Results: Data were obtained for 6 003 respondents, with mean age of 38.9 (95%CI 38.2‐39.6) years and 57.3% females. In the Portuguese population, the prevalence of ‘Current asthma’ was 6.8% (95%CI 6.0‐7.7) and of ‘Lifetime asthma’ was 10.5% (95%CI 9.5‐11.6) Using GA2LEN definition for asthma, our prevalence estimate was 7.8% (95%CI 7.0‐8.8). Rhinitis had a strong association with asthma (Adjusted OR 3.87, 95%CI 2.90‐5.18) and the association between upper airway diseases and asthma was stronger in patients with both rhinitis and sinusitis (Adjusted OR 13.93, 95%CI 6.60‐29.44).Conclusions: Current asthma affects 695 000 Portuguese, with a prevalence of 6.8%. People who reported both rhinitis and sinusitis had the highest risk of having asthma.

1 January 2014 in Clinical and Translational Allergy
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ASAna Sá-Sousa
Ana Sá-Sousa
TJTiago Jacinto
Tiago Jacinto
LALuís Azevedo
Luís Azevedo
MMMário Morais‐Almeida
Mário Morais‐Almeida
CRCarlos Robalo‐Cordeiro
Carlos Robalo‐Cordeiro
JFJoao A. da Fonseca
Joao A. da Fonseca
Objective: The best combination of questions to define asthma in epidemiological asthma studies is not known. We summarized the operational definitions of asthma used in prevalence studies and empirically assess how asthma prevalence estimates vary depending on the definition used.Methods: We searched the Thomson Reuters ISI Web of knowledge and included (1) cross‐sectional studies (2) on asthma prevalence (3) conducted in the general population and (4) containing an explicit definition of asthma. The search was limited to the 100 most‐cited papers or published since January 2010. For each paper, we recorded the asthma definition used and other variables. Then we applied the definitions to the data of the Portuguese National Asthma survey (INAsma) and of the 2005–2006 National Health and Nutrition Examination Survey (NHANES) computing asthma prevalence estimates for the different definitions.Results: Of 1738 papers retrieved, 117 were included for analysis. Lifetime asthma, diagnosed asthma and current asthma were defined in 8, 12 and 29 different ways, respectively. By applying definitions of current asthma on INAsma and NHANES data, the prevalence ranged between 5.3%‐24.4% and 1.1%‐17.2%, respectively.Conclusions: There is considerable heterogeneity in the definitions of asthma used in epidemiological studies leading to highly variable estimates of asthma prevalence. Studies to inform a standardized operational definition are needed. Meanwhile, we propose a set of questions to be reported when defining asthma in epidemiological studies.

15 January 2013 in Clinical and Translational Allergy
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AVAnnelies Verlaet
Annelies Verlaet
VGVanessa Garcia-Larsen
Vanessa Garcia-Larsen
ASAna Sá-Sousa
Ana Sá-Sousa
RBRenata Barros
Renata Barros
Rute SantosRute Santos
Rute Santos
JFJoao A. da Fonseca
Joao A. da Fonseca
Background: Though exercise‐induced bronchoconstriction is common among asthmatics, physical activity (PA) seems important in asthma management. Still, various studies point at avoidance of sports and certain daily life activities like walking stairs, even by patients with mild symptoms. We aimed to compare physical activity levels between healthy subjects and asthmatics with controlled and uncontrolled disease.Methods: Data on asthma and PA were drawn from the Portuguese National Asthma Survey. The short telephone version of the International Physical Activity Questionnaire (IPAQ) was used to measure PA levels. Current asthma was defined as self‐reported asthma and at least one of these criteria: one or more asthma symptoms in the last twelve months, currently taking asthma medication or an asthma medical appointment in the previous twelve months. Controlled asthma was defined as a CARAT global score > 24 or a CARAT second factor score ≤ 16. Healthy subjects were defined as individuals without atopy, heart disease or any respiratory symptom. X2 and Mann–Whitney/Kruskall‐Wallis tests were used to compare groups. Logistic regression analyses were performed to assess relations between asthma status and PA dimensions.Results: A total of 606 non‐asthmatics, 125 controlled and 78 uncontrolled asthmatic subjects were included. In both genders, overall PA level did not differ significantly between groups. Controlled (men) and uncontrolled (women) asthmatics did more vigorous PA than healthy respondents. Male controlled asthmatics also did more moderate PA. Crude logistic regression showed positive relations between daily sitting time, vigorous and moderate PA and controlled asthma in men and between vigorous PA and uncontrolled asthma in women. After adjustments for confounders, moderate PA remained a predictor of controlled asthma in men, while vigorous PA doubled the risk of uncontrolled asthma in women.Conclusion: Our study showed that adult asthmatics, independent of asthma control, do not seem to have a more sedentary lifestyle than their peers. Nevertheless, PA should be encouraged, as only about half of them reached activity recommendations.

17 August 2017 in Pediatric Allergy and Immunology
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MMManuel Ferreira de Magalhães
Manuel Ferreira de Magalhães
RARita Amaral
Rita Amaral
APAna Pereira
Ana Pereira
ASAna Sá-Sousa
Ana Sá-Sousa
IAInês Azevedo
Inês Azevedo
JFJoao A. da Fonseca
Joao A. da Fonseca