Dr. Prakash Kulkarni is a resident professor and director of translational research, Department of Medical Oncology, and holds a secondary appointment as resident professor in the Department of Systems Biology at the City of Hope National Medical Centre. After receiving his PhD in biochemistry from India, he completed his postdoctoral training in biochemistry at the Indian Institute of Science and subsequently in cell biology at New York University School of Medicine. He began his independent academic career as an assistant professor of urology and oncology at Johns Hopkins University, where he was named the Irene and Bernard L Schwartz Scholar of the Patrick C Walsh Prostate Research Fund. He then moved as a resident associate professor to the WM Keck Laboratory for Structural Biology, University of Maryland Institute for Bioscience and Biotechnology Research. Prior to Johns Hopkins, Dr. Kulkarni held staff scientist positions in the Division of Chemistry and Chemical Engineering and Division of Biology and Biological Engineering at the California Institute of Technology and in the Department of Genetics at Yale University School of Medicine. He is the associate editor-in-chief of Biomolecules. His research interests are focused on how conformational dynamics of intrinsically disordered proteins contribute to phenotypic switching, especially in the evolution of multicellularity, cancer, and non-genetic heterogeneity. He is a fellow of the Royal Society of Biology, UK.