Medical studies at universities in Bonn and Hamburg; doctoral thesis and degree in Bonn; specialization in Pathology and Medical Genetics, and habilitation at the Medcal University in Lübeck; head of a Germany-wide centralized foetal pathology following prenatal diagnostics. scientific activities in 'Fetal Pathology and Syndromology', spontaneous abortions and Cytogenetics ; head of the Institute of Clinical Genetics at the University in Marburg; honorary and guest professoships at the universities in Peking, Pavia and Vienna; Numerous invitations to universities in England, France, Spain, Italy, Croatia, Denmark and the USA; organization of 2 congrsses on Paediatric and Fetal Pathology; 14 grants; 4 awards; 169 publications including book articles; memberships in 16 medical societies; Deputy Chairwoman of the German Society for Human Genetics (4 years); Member of the Central Commission of the German Medical Association (5 years);