This paper focuses on predicting road passenger probability and optimizing taxi driving routes based on trajectory big data. By utilizing clustering algorithms to identify key passenger points, a method for calculating and predicting road passenger probability is proposed. This method calculates the passenger probability for each road segment during different time periods and uses a BiLSTM neural network for prediction. A passenger-seeking recommendation model is then constructed with the goal of maximizing passenger probability, and it is solved using the NSGA-II algorithm. Experiments are conducted on the Chengdu taxi trajectory dataset, using MSE as the metric for model prediction accuracy. The results show that the BiLSTM prediction model improves prediction accuracy by 9.67% compared to the BP neural network and by 6.45% compared to the LSTM neural network. The proposed taxi driver passenger-seeking route selection method increases the average passenger probability by 18.95% compared to common methods. The proposed passenger-seeking recommendation framework, which includes passenger probability prediction and route optimization, maximizes road passenger efficiency and holds significant academic and practical value.