Jialiang Han

Dr. Jialiang Han


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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Verified
Journal Article
Open access
PDF file
YLYingyong Luo
Yingyong Luo
YZYun-Feng Zhang
Yun-Feng Zhang
ZXZhuang Xiong
Zhuang Xiong
XCXiaodie Chen
Xiaodie Chen
ASAjia Sha
Ajia Sha
Qiang LiQiang Li
Qiang Li
In recent years, heavy metal pollution has become increasingly prominent, severely damaging ecosystems and biodiversity, and posing a serious threat to human health. However, the results of current methods for heavy metal restoration are not satisfactory, so it is urgent to find a new and effective method. Peptides are the units that make up proteins, with small molecular weights and strong biological activities. They can effectively repair proteins by forming complexes, reducing heavy metal ions, activating the plant’s antioxidant defense system, and promoting the growth and metabolism of microorganisms. Peptides show great potential for the remediation of heavy metal contamination due to their special structure and properties. This paper reviews the research progress in recent years on the use of peptides to remediate heavy metal pollution, describes the mechanisms and applications of remediation, and provides references for the remediation of heavy metal pollution.

5 June 2024 in Microorganisms
Verified
Journal Article
Open access
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ZXZhuang Xiong
Zhuang Xiong
YZYun-Feng Zhang
Yun-Feng Zhang
XCXiaodie Chen
Xiaodie Chen
ASAjia Sha
Ajia Sha
WXWenqi Xiao
Wenqi Xiao
Qiang LiQiang Li
Qiang Li
Microplastics (MPs), found in many places around the world, are thought to be more detrimental than other forms of plastics. At present, physical, chemical, and biological methods are being used to break down MPs. Compared with physical and chemical methods, biodegradation methods have been extensively studied by scholars because of their advantages of greenness and sustainability. There have been numerous reports in recent years summarizing the microorganisms capable of degrading MPs. However, there is a noticeable absence of a systematic summary on the technology for breeding strains that can degrade MPs. This paper summarizes the strain-breeding technology of MP-degrading strains for the first time in a systematic way, which provides a new idea for the breeding of efficient MP-degrading strains. Meanwhile, potential techniques for breeding bacteria that can degrade MPs are proposed, providing a new direction for selecting and breeding MP-degrading bacteria in the future. In addition, this paper reviews the sources and pollution status of soil MPs, discusses the current challenges related to the biodegradation of MPs, and emphasizes the safety of MP biodegradation.

27 May 2025 in Journal of Hazardous Materials
Verified
Journal Article
Closed access
WXWenqi Xiao
Wenqi Xiao
SCShuyi Chen
Shuyi Chen
MZMaojie Zhao
Maojie Zhao
DWDan Wen
Dan Wen
LPLianxin Peng
Lianxin Peng
Qiang LiQiang Li
Qiang Li

26 September 2025 in Frontiers in Genetics
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Journal Article
Open access
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JXJing Xiong
Jing Xiong
XWXianqiu Wang
Xianqiu Wang
XYXueling Ye
Xueling Ye
CLChangying Liu
Changying Liu
JHJialiang Han
Jialiang Han
Drought stress poses a significant threat to maize productivity, highlighting the need to elucidate molecular mechanisms underlying drought tolerance. Previous studies identified ZmLBD33 as a regulator of drought stress responses that interacts with the cell wall-loosening gene ZmEXPB7. To elucidate the function of ZmEXPB7 in drought tolerance, we conducted heterologous expression studies in Arabidopsis. The results demonstrated that ZmEXPB7 expression was rapidly induced under PEG6000-simulated stress, reaching peak levels within 1 h. Overexpression of ZmEXPB7 in Arabidopsis significantly enhanced drought tolerance, improved root growth, and increased survival rates under osmotic and soil drought conditions. Transgenic plants exhibited reduced water loss, decreased stomatal density, and enhanced stomatal closure. DAB and NBT staining demonstrated that the ROS accumulated in ZmEXPB7-overexpressed Arabidopsis. A physiological index assay also revealed that SOD and POD activities in ZmEXPB7-overexpressed Arabidopsis were lower than those in wild-type Arabidopsis. These findings indicate that ZmEXPB7 positively regulates drought tolerance by modulating stomatal aperture and H2O2 signaling. This study highlights the crucial role of expansin genes in stress adaptation and positions ZmEXPB7 as a potential target for engineering drought-resilient crops.

1 August 2025 in Diversity
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Journal Article
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JHJialiang Han
Jialiang Han
XFXing Fan
Xing Fan
AWAnkang Wu
Ankang Wu
BDBingnan Dong
Bingnan Dong
QZQixian Zou
Qixian Zou
The Mayanghe National Nature Reserve, a key habitat for the endangered François’ langur (Trachypithecus francoisi), faces significant anthropogenic disturbances, including extensive distribution of croplands, roads, and settlements. These human-modified features are predominantly concentrated at elevations between 500 and 800 m and on slopes of 10–20°, which notably overlap with the core elevation range utilized by François’ langur. Spatial analysis revealed that langurs primarily occupy areas within the 500–800 m elevation band, which comprises only 33% of the reserve but hosts a high density of human infrastructure—including approximately 4468 residential buildings and the majority of cropland and road networks. Despite slopes >60° representing just 18.52% of the area, langur habitat utilization peaked in these steep regions (exceeding 85.71%), indicating a strong preference for rugged karst terrain, likely due to reduced human interference. Habitat type analysis showed a clear preference for evergreen broadleaf forests (covering 37.19% of utilized areas), followed by shrublands. Landscape pattern metrics revealed high habitat fragmentation, with 457 discrete habitat patches and broadleaf forests displaying the highest edge density and total edge length. Connectivity analyses indicated that distribution areas exhibit a more continuous and aggregated habitat configuration than control areas. These results underscore François’ langur’s reliance on steep, forested karst habitats and highlight the urgent need to mitigate human-induced fragmentation in key elevation and slope zones to ensure the species’ long-term survival.

4 December 2025 in Pathogens
Verified
Journal Article
Open access
PDF file
PLPing Liu
Ping Liu
DWDan Wang
Dan Wang
FZFan Zhang
Fan Zhang
TWTao Wang
Tao Wang
JHJialiang Han
Jialiang Han
QZQixian Zou
Qixian Zou
Understanding the diversity of pathogenic microorganisms in wild primates is essential for assessing their health and zoonotic risks. In this study, metagenomic sequencing was applied to investigate the composition and seasonal dynamics of potential pathogenic microorganisms in the feces of François’ langurs. A total of 77 potential pathogenic taxa were identified, mainly belonging to Bacillota and Pseudomonadota. The most abundant genera were Streptococcus, Staphylococcus, Salmonella, Listeria, and Pseudomonas, while dominant species included Staphylococcus aureus, Streptococcus pneumoniae, Salmonella enterica, Listeria monocytogenes, and Escherichia coli. Significant seasonal differences were detected in both α- and β-diversity indices, with higher microbial diversity in spring and distinct community structures across seasons. Several genera and species, including Vibrio, Chlamydia, Mycobacteroides, Vibrio cholerae, Yersinia enterocolitica, Chlamydia trachomatis, and Mycobacteroides abscessus, showed marked seasonal fluctuations. The findings reveal that the pathogenic microbial community of François’ langurs is strongly shaped by seasonal environmental factors. The detection of multiple zoonotic pathogens suggests a potential risk of cross-species transmission, providing valuable baseline data for primate disease ecology and conservation health management.