We have devised a straightforward tandem postsynthetic modification strategy for Zr-based metal–organic framework (MOF) materials, which resulted in a series of well-defined 2-in-1 heterogeneous catalysts, cat1–cat8, exhibiting high catalytic activity in the synthesis of cyclic carbonates under solvent-free and co-catalyst-free conditions. The materials feature precisely located co-catalyst moieties decorating the metal nodes throughout the bulk of the MOF and yield cyclic carbonates with up to 99% efficiency at room temperature. We use diffuse reflectance infrared Fourier transform (DRIFT) and solid-state nuclear magnetic resonance (NMR) measurements to elucidate the role of each component in this model catalytic reaction. Establishing a method to precisely control the co-catalyst loading allowed us to observe the cooperativity between Lewis acid sites and the co-catalyst in the 2-in-1 heterogeneous system.

Imino-functionalized cage-like octasilsesquioxanes provide unique examples of the 3D supramolecular network and their relationship to the assembly of tunable materials from nanobuilding blocks.

The aim of this work was to develop an efficient approach to prepare a macroporous scaffold for sophisticated bone replacement, avoiding a long-lasting and complex methodology. Such a scaffold based on the 3-(trimethoxysilyl)propyl methacrylate–POSS hybrid was synthesized via the reaction of 3-(trimethoxysilyl)propyl methacrylate and the trifluoromethanesulfonate–POSS salt. The results show that the chemical composition, structural dimensions, topography, and microstructural properties of the scaffold fulfill the potential requirements for hard-tissue engineering. The microstructural properties were evaluated with the use of X-ray microcomputed tomography (micro-CT) and nanoindentation tests. The former makes it possible to estimate the geometrical measures of the microstructure (porosity, thickness distribution, etc.), whereas the latter makes it possible to estimate the mechanical properties of the constituents of the material (hardness, stiffness modulus, creep, etc.). The aforementioned laboratory testing methods are modern techniques, currently being developed for materials science, making it possible to determine the microstructural/measures of the analyzed system.

We present the synthetic and release aspects of a novel drug delivery system (DDS) based on amido-functionalized POSS. DDS after drug release hydrolyses at pH = 7.40 to non-toxic products such as carboxylic acid salts and aminopropyl-POSS.