Municipal solid waste management in developing countries faces limitations, especially concerning technologies for treatment and disposal, which is crucial for achieving environmental and economic sustainability goals. This paper investigates municipal solid waste management in Laos, compared with the ASEAN-Japan regions, focusing on background information, waste characteristics, environmental impact, and treatment technologies for resource utilization. The findings indicate a continuous rise in municipal waste generation in Laos, particularly in the capital Vientiane, from 0.21 million tons in 2012 to 0.37 million tons in 2021. Treatment methods include unsanitary landfilling, basic recycling, and open dumping, as well as burning or discharge into rivers, posing potential risks to the environment and human health. Japan and Singapore have shown decreasing trends, with Japan reducing from 45.23 million tons in 2012 to 40.95 million tons in 2021 and Singapore from 7.27 million tons in 2021 to 6.94 million tons in 2021. Laos encounters challenges in managing municipal waste, especially in waste recovery and waste-to-energy practices, crucial elements of integrated solid waste management aimed at promoting environmental and economic sustainability. Enhancing waste management in Laos involves developing a waste management act with segregation, recycling, and extended producer responsibility policies. Implementing mechanical biological treatment facilities, waste-to-energy plants, and upgraded landfills is crucial. Capacity building and public awareness campaigns on waste management will improve sustainability, reduce environmental impacts, and advance sustainable development goals for sustainable cities and communities.