Apart from the significant progress the scientific community has made during the last few decades, inflammation-mediated kidney-related diseases like chronic and diabetic kidney diseases (CKD and DKD) and glomerulosclerosis still continue to raise mortality rates. Recently, conventional therapeutic interventions have been put aside, since natural vitamin D-derived treatment has gained attention and offered several promising outcomes. Within this article, the utilization of vitamin D and its analogues as potential treatment toward kidney-related diseases, due to their anti-inflammatory, antioxidant and anti-fibrotic activity, is outlined. Vitamin D analogues including calcitriol, paricalcitol and 22-oxacalcitriol have been previously explored for such applications, but their hidden potential has yet to be further elucidated. Several clinical trials have demonstrated that vitamin D analogues’ supplementation is correlated with inflammatory signaling and oxidative stress regulation, immunity/metabolism augmentation and subsequently, kidney diseases and healthcare-related infections’ prevention, and the results of these trials are thoroughly evaluated. The highlighted research outcomes urge further study on a plethora of vitamin D analogues with a view to fully clarify their potential as substantial anti-inflammatory constituents of renal diseases-related treatment and their health-promoting properties in many kidney-associated healthcare complications and infections.

A novel method for quantifying tortuosity by analyzing the pressure distribution of gas within a rotating porous bed is presented. The method utilizes a custom-designed disc-shaped cell packed with activated carbon particles and subjected to a high-speed rotation of 5000 rpm under an equilibrium initial pressure of 5045 mbar CO₂. The theory related to this method is outlined. From the radial pressure distribution, the apparent tortuosity is estimated to be ~2.3. This value is independently validated using an extracted apparent diffusion coefficient of D_app = (9.7 ± 0.3) × 10⁻⁷ m²/s and a corresponding tortuosity of τ_app = 2.2 ± 0.8. The findings establish a new route for probing the interplay between pore geometry, gas transport, and adsorption phenomena under centrifugal forces.