The aim of the current study was to investigate whether a Total Lifestyle Index (TLI), including adherence to the Mediterranean diet, sleep duration, physical activity and engagement in activities of daily living, is associated with cognitive health over time and dementia risk, in a representative cohort of older people. A total of 1018 non-demented community-dwelling older adults ≥65 years old (60% women) from the HELIAD study were included. A comprehensive neurological and neuropsychological assessment was conducted at baseline and at the 3-year follow-up evaluating cognitive functioning, and a dementia diagnosis was set. Diet, physical activity, sleep duration and engagement in activities of daily living were assessed using standard, validated questionnaires at baseline. Sixty-one participants developed dementia at follow-up; participants who developed dementia were older and had fewer years of education compared with participants with normal cognition. With the exception of sleep duration, participants with normal cognition at follow-up scored higher in the individual lifestyle factors compared to those who developed dementia. Regarding TLI, values were lower for participants with dementia compared with those with normal cognition. Each additional unit of the TLI was associated with 0.5% of a standard deviation less decline per year of the Global Cognition score, whereas for each additional unit of the TLI, the risk for dementia was reduced by 0.2% per year (p < 0.05). Our results suggest that greater adherence to a healthy lifestyle pattern is associated with a slower decline of cognitive function and reduced dementia risk.
25 March 2022 in The Journal of Nutritional Biochemistry
Hysterosalpingography (HSG) is an imaging method performed to assess tubal occlusion in cases of infertility, ectopic pregnancy, and hyperplasia. Although venous intravasation (VI) is a rare occurrence during HSG, it is associated with thromboembolic episodes and misinterpreted HSG. We present a rare case report of a 41-year-old female who underwent HSG and the introduction of contrast medium to the pelvic drainage system via the uterine cavity and the myometrium.
Supernumerary kidney (SNK) is a rare congenital anatomical variation usually detected incidentally via imaging. Although a random finding, it may present with hydronephrosis, calculi or malignancy. Both its vascularization and its drainage vary significantly, depending on its location and shape. Riedel’s lobe is a normal, though rare, variant of liver anatomy presenting either as a downward projection of the inferior border of the right liver lobe or as a triangular pyramidoid projection to the right of the gallbladder. We present a case of a 71-year-old man who was initially admitted to the hospital for backache. Computed tomography (CT) imaging revealed the simultaneous occurrence of a left supernumerary kidney and Riedel’s lobe. The SNK lay caudally to the normal kidney, it was supplied by a branch of the superior mesenteric artery and its drainage was supported by a bifid ureter. The Riedel’s lobe represented the “tongue-like” variant without causing any symptoms to the patient. Both entities should be monitored carefully, as their presence may require surgical management should they raise a sequence of symptoms or, as in this case, modify the surgical plans in the context of other coexisting medical events.
Purpose: To retrospectively evaluate the feasibility of a coaxial guide with a spring-loaded blunt-tip stylet during single session biopsy and microwave ablation (MWA) of T1 renal cell carcinoma. Materials and methods: Institutional database research identified all patients who underwent concomitant percutaneous, computed tomography-guided biopsy and microwave ablation. A 15-gauge coaxial guide with a spring-loaded blunt-tip stylet was percutaneously placed in the target tumor. Coaxially, an 18-gauge biopsy needle was first inserted for sampling, followed by the insertion of a 16-gauge microwave probe. Diagnostic yield, oncologic outcomes, and safety were assessed. International guidelines were used for ablation terminology, and the modified CIRSE classification system was used for complication reporting. All patients were followed up for at least 2 years with either CT or MRI scan. Results: A total of 15 patients (mean age: 67.8 ± 3.4 years) with 17 renal tumors (mean diameter 2.77 ± 0.43 cm) were evaluated. Technical success was achieved in all cases. Diagnostic yield was 100% (clear cell RCC n = 13, papillary RCC n = 3, oncocytoma: n = 1). Overall, metastasis-free survival (MFS) was 100% at 2 years, while recurrence-free survival (RFS) was 100% at 1 year and 94.12% at 2 years. One patient (6.67%) demonstrated local recurrence during the 1-year follow-up, and the patient subsequently underwent surgical intervention (radical nephrectomy). Grade 1a complications were recorded in 2 patients (13.3%), consisting of limited perinephric hematomas that required only observation. Conclusion: Based on the preliminary current results concomitant performance of percutaneous biopsy and microwave ablation using a coaxial biopsy guide with spring-loaded blunt tip stylet is feasible, safe and efficacious for the management of T1 renal cell cancer.
6 September 2026 in CardioVascular and Interventional Radiology