Kadanthottu Sebastian Joseph

Dr. Kadanthottu Sebastian Joseph

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Research Focus & Metrics

Academic Career Length

13Years (2014-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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8 March 2023 in Antibiotics
Verified
Journal Article
Open access
PDF file
JJJuhi Jaison
Juhi Jaison
Balamuralikrishnan BalasubramanianBalamuralikrishnan Balasubramanian
Balamuralikrishnan Balasubramanian
JGJaya Gangwar
Jaya Gangwar
NJNilina James
Nilina James
MPManikantan Pappuswamy
Manikantan Pappuswamy
KJKadanthottu Sebastian Joseph
Kadanthottu Sebastian Joseph
The Asteraceae family is one of the largest families in the plant kingdom with many of them extensively used for significant traditional and medicinal values. Being a rich source of various phytochemicals, they have found numerous applications in various biological fields and have been extensively used for therapeutic purposes. Owing to its potential phytochemicals present and biological activity, these plants have found their way into pharmaceutical industry as well as in various aspects of nanotechnology such as green synthesis of metal oxide nanoparticles. The nanoparticles developed from the plants of Asteraceae family are highly stable, less expensive, non-toxic, and eco-friendly. Synthesized Asteraceae-mediated nanoparticles have extensive applications in antibacterial, antifungal, antioxidant, anticancer, antidiabetic, and photocatalytic degradation activities. This current review provides an opportunity to understand the recent trend to design and develop strategies for advanced nanoparticles through green synthesis. Here, the review discussed about the plant parts, extraction methods, synthesis, solvents utilized, phytochemicals involved optimization conditions, characterization techniques, and toxicity of nanoparticles using species of Asteraceae and their potential applications for human welfare. Constraints and future prospects for green synthesis of nanoparticles from members of the Asteraceae family are summarized.

21 July 2023 in Journal of Umm Al-Qura University for Applied Sciences
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Journal Article
Open access
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PCPreethy Chandran
Preethy Chandran
SSSneha Suresh
Sneha Suresh
BBBalamuralikrishnan Balasubramain
Balamuralikrishnan Balasubramain
JGJaya Gangwar
Jaya Gangwar
ARAsha S. Raj
Asha S. Raj
KJKadanthottu Sebastian Joseph
Kadanthottu Sebastian Joseph
Human needs have led to the development of various products which are produced in the industries. These industries in turn have become a source of various environmental concerns. As industries release regulated and unregulated contaminants into the water bodies, it has become a serious concern for all living organisms. Various emerging contaminates from industries like pesticides, pharmaceuticals drugs like hormones, antibiotics, dyes, etc., along with byproducts and new complexes contaminate the water bodies. Numerous traditional approaches have been utilized for the treatment of these pollutants; however, these technologies are not efficient in most cases as the contaminants are mixed with complex structures or as new substances. Advanced technologies such as bioreactor techniques, advanced oxidation processes, and so on have been used for the treatment of industrial wastewater and have served as an alternative way for wastewater treatment. Overall, biological treatment techniques based on bioreactors provide a long-term and ecologically useful solution to industrial wastewater contamination. They play an important role in saving water resources and encouraging a greener sustainable future for mankind. The current review outlines the industrial effluents that are released into water bodies, contaminating them, as well as the numerous traditional and novel treatment procedures used for industrial wastewater treatment. Graphical abstract

30 January 2024 in Efood
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Journal Article
Open access
SSShilpa Susan Scaria
Shilpa Susan Scaria
Balamuralikrishnan BalasubramanianBalamuralikrishnan Balasubramanian
Balamuralikrishnan Balasubramanian
AMArun Meyyazhagan
Arun Meyyazhagan
JGJaya Gangwar
Jaya Gangwar
JJJuhi Puthukulangara Jaison
Juhi Puthukulangara Jaison
KJKadanthottu Sebastian Joseph
Kadanthottu Sebastian Joseph
Cassava (Manihot esculenta Crantz) is believed to be an important staple food crop providing potential valuable food source as well as variety of phytoconstituents. Its starchy tubers provide a significant source of energy for around 500 million individuals. Among staple crops, it is regarded to be one of the top suppliers of carbohydrates. Its physicochemical qualities, as well as its availability, have made it a captivating food component. Cassava starch is a valuable raw material used to make a variety of both native and modified starch for cooking purposes. They have also been used for a variety of industrial uses. Cassava starch and flour have the potential to be valuable alternatives to rice, maize, and wheat crops. The advantages included being a staple diet for humans, a component of animal feeds, a raw ingredient for food processing, edible coatings, locally produced alcoholic beverages, and ethanol manufacturing. The roots consist of cyanogenic glycosides, which can lead to lethal cyanide poisoning if tubers arse not properly detoxified using different processing methods include washing, fermentation, boiling, peeling and chemical processing to escape toxin content. The current review summarizes cassava's bioactive components which could be a potential source of various pharmaceutical drugs as well as a source of traditional and modern food applications.

26 December 2022 in Metabolites
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Journal Article
Open access
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HMHosakatte Niranjana Murthy
Hosakatte Niranjana Murthy
KJKadanthottu Sebastian Joseph
Kadanthottu Sebastian Joseph
KPKee-Yoeup Paek
Kee-Yoeup Paek
SPSo-Yung Park
So-Yung Park
The Rubia genus includes major groups of medicinal plants such as Rubia cordifolia, Rubia tinctorum, and Rubia akane. They contain anthraquinones (AQs), particularly alizarin and purpurin, which have pharmacological effects that are anti-inflammatory, antioxidant, anticancer, hemostatic, antibacterial, and more. Alizarin and purpurin have been utilized as natural dyes for cotton, silk, and wool fabrics since the dawn of time. These substances have been used in the cosmetics and food industries to color products. The amount of AQs in different Rubia species is minimal. In order to produce these compounds, researchers have established cell and organ cultures. Investigations have been conducted into numerous chemical and physical parameters that affect the biomass and accumulation of secondary metabolites in a cell, callus, hairy root, and adventitious root suspension cultures. This article offers numerous techniques and approaches used to produce biomass and secondary metabolites from the Rubia species. Additionally, it has been emphasized that cells can be grown in bioreactor cultures to produce AQs.

4 January 2023 in Physiology and Molecular Biology of Plants
Verified
Journal Article
Closed access
PDF file
JGJaya Gangwar
Jaya Gangwar
KJKadanthottu Sebastian Joseph
Kadanthottu Sebastian Joseph
JJJuhi Puthukulangara Jaison
Juhi Puthukulangara Jaison
JKJissa Theresa Kurian
Jissa Theresa Kurian

31 December 2023 in Plants
Verified
Journal Article
Open access
PDF file
HMHosakatte Niranjana Murthy
Hosakatte Niranjana Murthy
KJKadanthottu Sebastian Joseph
Kadanthottu Sebastian Joseph
KPKee-Yoeup Paek
Kee-Yoeup Paek
SPSo-Yung Park
So-Yung Park
Anthocyanins are water-soluble pigments found in plants. They exist in various colors, including red, purple, and blue, and are utilized as natural colorants in the food and cosmetics industries. The pharmaceutical industry uses anthocyanins as therapeutic compounds because they have several medicinal qualities, including anti-obesity, anti-cancer, antidiabetic, neuroprotective, and cardioprotective effects. Anthocyanins are conventionally procured from colored fruits and vegetables and are utilized in the food, pharmaceutical, and cosmetic industries. However, the composition and concentration of anthocyanins from natural sources vary quantitively and qualitatively; therefore, plant cell and organ cultures have been explored for many decades to understand the production of these valuable compounds. A great deal of research has been carried out on plant cell cultures using varied methods, such as the selection of suitable cell lines, medium optimization, optimization culture conditions, precursor feeding, and elicitation for the production of anthocyanin pigments. In addition, metabolic engineering technologies have been applied for the hyperaccumulation of these compounds in varied plants, including tobacco and arabidopsis. In this review, we describe various strategies applied in plant cell and organ cultures for the production of anthocyanins.