MESUT BAKIR

Dr. MESUT BAKIR

orcid

Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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14 February 2017 in Journal of Anesthesia
Verified
Journal Article
Closed access
PDF file
DODerya Ozkan
Derya Ozkan
EGEmel Gonen
Emel Gonen
TATaylan Akkaya
Taylan Akkaya
MBMESUT BAKIR
MESUT BAKIR

14 September 2023 in Cureus
Verified
Journal Article
Open access
PDF file
MBMESUT BAKIR
MESUT BAKIR
ŞRŞebnem Rumeli
Şebnem Rumeli
APArgun Pire
Argun Pire
Objectives A multimodal approach to pain management, including potential interventional techniques, is suggested to achieve adequate pain control. This study discusses the techniques and medications employed to manage pain in pediatric oncology patients. Methodology This study included 90 patients under 18 years of age who underwent pain management in the algology clinic between 2002 and 2020. From the algology follow-up records, the following data were recorded: demographic information, follow-up time, cancer diagnosis and stage, cause and location of pain, systems involved, duration and intensity of pain, analgesic and adjuvant drugs prescribed, routes and duration of drug administration, complications, interventional procedures if performed, “pain intensity” scores prior to and following treatment, and daily and total analgesic consumption of the patients. Results The mean age was 11.4±4.1 years (min-max: 2-17). Leukemia and lymphoma were the most frequently diagnosed (30%). Of the 31 features identified in the staging, 27 (87.1%) were stage 4 at admission. The causes of pain in children were neoplasms in 81.2% (n = 73). At admission, 72.3% (n = 65) had severe pain for at least a month. It was determined that 90% (n = 81) of the patients were using opioids and 28.9% (n = 26) were using dual opioids. The mean tramadol dose was 129.0±97.9 mg/day (12-380 mg/day), and the mean morphine dose was 14.8±11.3 mg/day (1-52 mg/day). The mean transdermal fentanyl dose was 33.2±21.6 µgr/h (12-75 µgr/h). Adjuvant therapy was administered in 25.6% (n = 24) of the patients. Epidural catheterization was performed on 6.6% (n = 6) of the patients. The mean initial pain scores were 5.2±1.7, which decreased to 1.5±0.7 with a significant difference (p < 0.001). In the study, 93% (n = 84) of the patients had no pain management complications noted. Conclusions The pain level that pediatric cancer patients endure critically influences their and their family’s quality of life. The fact that opioid-related adverse effects associated with pediatric pain management occur far less frequently than previously thought may help prevent opiophobia. Effective and safe analgesia can be provided with multimodal analgesia to manage pediatric cancer pain.

18 December 2024 in Traumatology and Orthopedics of Russia
Verified
Journal Article
Open access
PDF file
MBMESUT BAKIR
MESUT BAKIR
ŞRŞebnem Rumeli
Şebnem Rumeli
Background. The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has prompted the widespread use of corticosteroids as a treatment strategy, particularly in cases of severe pneumonia and cytokine storm. While this therapy has saved countless lives, its side effects have also been well-documented, including the development of avascular necrosis. Case presentation. This case report presents a rare instance of simultaneous bilateral avascular necrosis (AVN) affecting both the humeral and femoral heads in a 49-year-old male patient recovering from severe COVID-19. The patient was treated with high-dose corticosteroids, receiving 1250 mg of prednisolone over five days during hospitalization for COVID-19 pneumonia. Six months after discharge, he developed persistent hip pain, which was later diagnosed as AVN in both femoral heads. During hyperbaric oxygen therapy, the patient reported new shoulder pain, and MRI confirmed stage III AVN in both humeral heads. The patient’s pain was managed with bilateral suprascapular nerve radiofrequency ablation and bilateral Pericapsular Nerve Group (PENG) blocks, which provided significant relief. Conclusions. This case emphasizes the potential for corticosteroid-induced AVN, even months after treatment, and underscores the need for long-term monitoring of patients receiving corticosteroids for COVID-19. The involvement of four major joints highlights the severe musculoskeletal complications that can arise, supporting the importance of early diagnosis and timely intervention for pain relief.

19 September 2024 in Life
Verified
Journal Article
Open access
PDF file
MBMESUT BAKIR
MESUT BAKIR
ŞRŞebnem Rumeli
Şebnem Rumeli
MEMehmet Ertargin
Mehmet Ertargin
NTNurettin Teker
Nurettin Teker
MAMustafa Azizoğlu
Mustafa Azizoğlu
GTGülçin Gazioğlu Türkyılmaz
Gülçin Gazioğlu Türkyılmaz
Chronic lumbar facet pain is commonly treated with fluoroscopy-guided facet medial branch blocks (FMBBs). However, the associated radiation exposure of both patients and clinicians is a growing concern. This study aimed to compare radiation doses and fluoroscopy times between two techniques, i.e., oblique and posterior–anterior (PA) fluoroscopic approaches, while also examining the impact of physician experience on these metrics. A retrospective analysis was conducted on 180 patients treated at Mersin University Hospital Pain Clinic between January and July 2024. Patients were divided into two groups: 90 received the oblique technique (Group O) and 90 received the AP technique (Group A). Radiation dose and fluoroscopy time data were collected for each patient. The AP technique was associated with significantly lower radiation doses (mean 66 mGy) and shorter fluoroscopy times (mean 28 s) compared to the oblique technique (mean radiation dose of 109 mGy and fluoroscopy time of 46 s) (p < 0.001). Physician experience also influenced these outcomes, with more experienced physicians consistently using less radiation. The AP technique should be considered for FMBBs, as it reduces radiation exposure while maintaining procedural efficiency, highlighting the importance of experience in optimizing outcomes.

16 June 2023 in Turkish Journal of Anaesthesiology and Reanimation
Verified
Journal Article
Open access
MBMESUT BAKIR
MESUT BAKIR
ŞRŞebnem Rumeli
Şebnem Rumeli
ÜDÜmit Durmuşoğlu
Ümit Durmuşoğlu
EBErman Balıkçı
Erman Balıkçı
Lumbar puncture (LP) is performed by specialists in different branches of medicine, complications may be encountered in various settings. In our study, we evaluated the awareness and knowledge of the diagnosis and treatment of post-dural puncture headache (PDPH) among specialists who performed LP and/or encountered complications. This was a prospective questionnaire/scale study of 253 physicians: LP performers (anaesthesiologists, Group A; others, Group B) and those who worked in departments that did not perform LP but frequently encountered complications following LP (Group C). The questionnaire assessed specialization, frequency of LPs utilization, needle types used, positions employed, awareness of LP complications, diagnosis, management, and risk factors for PDPH. Group A had the highest percentage of physicians who stated they had knowledge about PDPH (Group A: 96.4%, Group B: 77.3%, Group C: 39.4%; P=0.000). Group C was found to be statistically less informed than the other two groups (P=0.000). It was determined that only one (1%) physician from Group C correctly answered the question about the diagnostic criteria for PDPH. To our knowledge this is the first study in which the awareness of PDPH has been compared according to physicians’ fields of specialisation. We believe that post-specialty training programs should be organized for physicians who will either perform LP or monitor patients who have undergone LP, and the curriculum content in relevant specialties should be reviewed.

3 December 2025 in Journal of Oral & Facial Pain and Headache
Verified
Journal Article
Open access
MBMESUT BAKIR
MESUT BAKIR
GTGülçin Gazioğlu Türkyılmaz
Gülçin Gazioğlu Türkyılmaz
NTNurettin Teker
Nurettin Teker
KYKaan Yavuz
Kaan Yavuz
BIBedri İlCan
Bedri İlCan
ŞRŞebnem Rumeli
Şebnem Rumeli
Background: Trigeminal neuralgia (TN) is a debilitating neuropathic pain condition with profound quality of life impact. This study aims to compare the clinical outcomes of Gasserian ganglion conventional radiofrequency (CRF) and peripheral nerve pulsed radiofrequency (PRF) in patients with TN. Methods: This retrospective cohort study included 74 patients with TN who underwent radiofrequency ablation (RFA) between January 2015 and June 2025 at a tertiary university pain clinic. Patients were divided into two groups: Group A (Gasserian CRF, n = 37) and Group B (Peripheral PRF, n = 37). Numerical Rating Scale (NRS) were recorded at baseline and at 1st, 3rd, and 6th months after treatment. Patient satisfaction was evaluated using a 5-point Likert scale for those with documented records. Results: Both groups showed significant pain relief at the 1st month compared to baseline (p < 0.001 for both). But, Group A showed significantly greater pain relief at the 3rd (3.54 ± 2.21 vs. 5.51 ± 2.91; p = 0.0035) and 6th months (3.19 ± 1.97 vs. 6.08 ± 3.06; p = 0.0001) than Group B. Mean satisfaction scores were significantly higher in Group A (21.76 ± 5.30) compared to Group B (14.19 ± 8.78), with a statistically significant difference (p < 0.001). Likert scores correlated strongly with 6-month NRS values (Spearman’s ρ = −0.91, p = 0.002). Linear regression also confirmed that lower pain scores at 6 months significantly predicted higher satisfaction (β = −2.75, R2 = 0.18, p = 0.003). Conclusions: Gasserian CRF appears more effective than peripheral PRF to ensure long-term pain relief in TN, and this may contribute to a trend toward higher patient satisfaction. Despite its invasiveness, CRF remains a valuable option for TN management. These findings support individualized procedural selection based on patient profiles and therapeutic goals. Clinical Trial Registration: The study was retrospectively registered on ClinicalTrials.gov (Identifier: NCT07013500).