Mario Krammel

Dr. Mario Krammel

orcid

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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13 January 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
MKMario Krammel
Mario Krammel
VDValentin Drahohs
Valentin Drahohs
THThomas Hamp
Thomas Hamp
SLSabine Lemoyne
Sabine Lemoyne
DGDaniel Grassmann
Daniel Grassmann
SSSebastian Schnaubelt
Sebastian Schnaubelt
Background: The city of Vienna, Austria, has a gradually aging population. Elderly people, over 65 years old and living at home or in nursing homes, frequently use Emergency Medical Services (EMS). However, there is no previous data comparing the EMS utilization of elderly- and non-elderly patients in Vienna. Methods: We retrospectively analyzed all EMS incidents in Vienna from 2012 to 2019. Transport- and emergency physician treatment rates, annual fluctuations, and the number of non-transports were compared between elderly (≥65 years) and non-elderly (18–64 years) patients. Results: Elderly people accounted for 42.6% of the total EMS responses in adult patients, representing an annual response rate of 223 per 1000 inhabitants ≥ 65 years. Compared to 76 per 1000 inhabitants in patients 18–64 years old, this results in an incidence rate ratio (IRR) of 2.93 [2.92–2.94]. Elderly people were more likely (OR 1.68 [1.65–1.70]) to need emergency physicians, compared to 18–64 year-olds. Nursing home residents were twice (OR 2.11 [2.06–2.17]) as likely to need emergency physicians than the rest of the study group. Non-transports were more likely to occur in patients over 65 years than in non-elderlies (14% vs. 12%, p < 0.001). Conclusions: The elderly population ≥ 65 years in Vienna shows higher EMS response rates than younger adults. They need emergency physicians more often, especially when residing in nursing homes. The economical and organizational strain this puts on the emergency response system should trigger further research and the development of solutions, such as specific response units dedicated to elderly people.

Verified
Journal Article
Open access
PDF file
MKMario Krammel
Mario Krammel
JEJakob Eichelter
Jakob Eichelter
CGConstantin Gatterer
Constantin Gatterer
ELElisabeth Lobmeyr
Elisabeth Lobmeyr
MNMarco Neymayer
Marco Neymayer
SSSebastian Schnaubelt
Sebastian Schnaubelt
Background: Police first responder systems also including automated external defibrillation (AED) has in the past shown considerable impact on favourable outcomes after out-of-hospital cardiac arrest (OHCA). While short hands-off times in chest compressions are known to be beneficial, various AED models use different algorithms, inducing longer or shorter durations of crucial timeframes along basic life support (BLS). Yet, data on details of these differences, and also of their potential impact on clinical outcomes are scarce. Methods: For this retrospective observational study, patients with OHCA of presumed cardiac origin and initially shockable rhythm treated by police first responders in Vienna, Austria, between 01/2013 and 12/2021 were included. Data from the Viennese Cardiac Arrest Registry and AED files were extracted, and exact timeframes were analyzed. Results: There were no significant differences in the 350 eligible cases in demographics, return of spontaneous circulation, 30-day survival, or favourable neurological outcome between the used AED types. However, the Philips HS1 and -FrX AEDs showed immediate rhythm analysis after electrode placement (0 [0–1] s) and almost no shock loading time (0 [0–1] s), as opposed to the LP CR Plus (3 [0–4] and 6 [6–6] s, respectively) and LP 1000 (3 [2–10] and 6 [5–7] s, respectively). On the other hand, the HS1 and -FrX had longer analysis times of 12 [12–16] and 12 [11–18] s than the LP CR Plus (5 [5–6] s) and LP 1000 (6 [5–8] s). The duration from when the AED was turned on until the first defibrillation were 45 [28–61] s (Philips FrX), 59 [28–81] s (LP 1000), 59 [50–97] s (HS1), and 69 [55–85] s (LP CR Plus). Conclusion: In a retrospective analysis of OHCA-cases treated by police first responders, we could not find significant differences in clinical patient outcomes concerning the respective used AED model. However, various differences in time durations (e.g., electrode placement to rhythm analysis, analysis duration, or AED turned on until first defibrillation) along the BLS algorithm were seen. This opens up the question of AED-adaptations and tailored training methods for professional first responders.

1 June 2024 in Circulation: Cardiovascular Quality and Outcomes
Verified
Journal Article
Open access
AGAnne Juul Grabmayr
Anne Juul Grabmayr
FFFredrik Folke
Fredrik Folke
JKJulie Samsoee Kjoelbye
Julie Samsoee Kjoelbye
LALinn Andelius
Linn Andelius
MKMario Krammel
Mario Krammel
CHCarolina Malta Hansen
Carolina Malta Hansen
BACKGROUND: Strategies to reach out-of-hospital cardiac arrests (called cardiac arrest) in residential areas and reduce disparities in care and outcomes are warranted. This study investigated incidences of cardiac arrests in public housing areas. METHODS: This register-based cohort study included cardiac arrest patients from Amsterdam (the Netherlands) from 2016 to 2021, Copenhagen (Denmark) from 2016 to 2021, and Vienna (Austria) from 2018 to 2021. Using Poisson regression adjusted for spatial correlation and city, we compared cardiac arrest incidence rates (number per square kilometer per year and number per 100 000 inhabitants per year) in public housing and other residential areas and examined the proportion of cardiac arrests within public housing and adjacent areas (100-m radius). RESULTS: Overall, 9152 patients were included of which 3038 (33.2%) cardiac arrests occurred in public housing areas and 2685 (29.3%) in adjacent areas. In Amsterdam, 635/1801 (35.3%) cardiac arrests occurred in public housing areas; in Copenhagen, 1036/3077 (33.7%); and in Vienna, 1367/4274 (32.0%). Public housing areas covered 42.4 (12.6%) of 336.7 km 2 and 1 024 470 (24.6%) of 4 164 700 inhabitants. Across the capitals, we observed a lower probability of 30-day survival in public housing versus other residential areas (244/2803 [8.7%] versus 783/5532 [14.2%]). The incidence rates and rate ratio of cardiac arrest in public housing versus other residential areas were incidence rate, 16.5 versus 4.1 n/km 2 per year; rate ratio, 3.46 (95% CI, 3.31–3.62) and incidence rate, 56.1 versus 36.8 n/100 000 inhabitants per year; rate ratio, 1.48 (95% CI, 1.42–1.55). The incidence rates and rate ratios in public housing versus other residential areas were consistent across the 3 capitals. CONCLUSIONS: Across 3 European capitals, one-third of cardiac arrests occurred in public housing areas, with an additional third in adjacent areas. Public housing areas exhibited consistently higher cardiac arrest incidences per square kilometer and 100 000 inhabitants and lower survival than other residential areas. Public housing areas could be a key target to improve cardiac arrest survival in countries with a public housing sector.

1 September 2025 in Open Access Emergency Medicine
Verified
Journal Article
Open access
PDF file
MKMario Krammel
Mario Krammel
DGDaniel Grassmann
Daniel Grassmann
LHLukas Heinrich
Lukas Heinrich
RBRoman Brock
Roman Brock
AKAndrea Kornfehl
Andrea Kornfehl
SSSebastian Schnaubelt
Sebastian Schnaubelt
Background: Manual ventilation is a critical skill for emergency medical service (EMS) members. However, it is challenging in terms of correct ventilation rates and tidal volumes, with potentially severe adverse effects of hypo- and hyperventilation. Measuring the quality and involving real-time feedback may be effective in optimizing of manual ventilation. Methods: Data acquired retrospectively from a quality management project in 143 advanced emergency medical technicians were included. They performed bag ventilations on an intubated adult manikin for two minutes without any feedback system, and then another two minutes with the Real BVM Help® device. Ventilation rates and volumes and their allocation in correct/recommended ranges were determined. Results: With the feedback device, correctly applied ventilation rates increased by 21% (63.6% in the correct range without vs 84.6% with the feedback device; p< 0.001), and ventilation volumes improved by 41% (27% in the correct range without vs 68% with the feedback device; p< 0.001). Without the device, the average ventilation rate was 10.5 ± 3.1/minute, compared to 9.5 ± 1.9/minute with the device. Ventilation volumes amounted to 370.6 ± 84 mL without Real BVM Help®, while when using it, 415.5 ± 33.1 mL was noted. Conclusion: Our data demonstrate significant improvements in ventilation rates and volumes when using a ventilation feedback device. This manikin study suggests a ventilation feedback device being beneficial for the use by EMS members, but our findings must be further validated in real-life conditions. Plain Language Summary: For various emergency situations in the out-of-hospital setting, it is important for ambulance personnel to be able to perform manual ventilations using a ventilation bag on patients. This critical skill is, however, difficult to acquire and maintain. Ventilating too little or too much are common challenges. Thus, measuring (with a so-called “feedback device”) how much air is given and how many times per minute may support paramedics. We thus conducted a data analysis of paramedics ventilating manikins with and without a feedback device, and we observed the allocation in correct/recommended ranges. Correctly applied ventilations increased significantly with the use of a feedback device. Our data thus suggests a ventilation feedback device being beneficial for the use by paramedics, but our findings must be further validated with real patients instead of manikins.

13 April 2023 in Anästhesie Nachrichten
Verified
Journal Article
Closed access
PDF file
MPMichael Poppe
Michael Poppe
IMIngrid Magnet
Ingrid Magnet
MKMario Krammel
Mario Krammel

Verified
Journal Article
Open access
PDF file
RBRoman Brock
Roman Brock
MKMario Krammel
Mario Krammel
AKAndrea Kornfehl
Andrea Kornfehl
CVChristoph Veigl
Christoph Veigl
BSBenedikt Schnaubelt
Benedikt Schnaubelt
SSSebastian Schnaubelt
Sebastian Schnaubelt
Background: Long-distance running impacts many organ systems. Aside from musculoskeletal and cardiopulmonary events, the gastrointestinal and renal system as well as metabolic homeostasis and electrolyte balance can be affected. A respective medical support strategy enabling rapid diagnosis, triage, and treatment in the context of large sports events is thus of utmost importance. Incidents can be assessed and graded via point-of-care (POC) blood gas analysis (BGA). We thus aimed to evaluate the feasibility and benefits of its use during a large sports event. Methods: All documented patient contacts during the race of the Vienna City Marathon (VCM) 2023 were retrospectively assessed. Additionally, the BGAs conducted in all patients requiring intravenous access were analyzed. Data are presented in a descriptive manner. Results: There were 39,871 participants at the VCM 2023. Of these, 277 (0.7%) required medical support, localized most commonly in the finishing area of the race (n = 239, 86% of all incidents). Fifty-eight (20.9%) patients had to be hospitalized. The most frequent chief complaints were syncope or collapse (24.9%), followed by general pain (20.6%) and trauma (14.8%). Five patients (1.8%) suffered from seizures, and one experienced (0.4%) from spontaneous pneumothorax. Thirty-one patients (11.2%) received venous blood gas analyses, showing mean creatinine levels of 1.82 (±0.517) mg/dL, mean lactate concentrations of 6.03 (±4.5) mmol/L, mean pH of 7.42 (±0.0721), and a mean base excess of −0.72 (±3.72) mmol/L. No cases of hyponatremia occurred in the documented samples. In eight cases (25.8%), sodium concentrations were above 145 mmol/L, with a maximum of 149 mmol/L. No cardiac arrests occurred. Conclusions: The physical exertion during the assessed long-distance running race resulted in numerous contacts with the medical support teams. The use of POC BGA at a large-scale marathon event was shown to be easy and feasible, allowing for more extensive diagnostics on-site. It can be integrated into a medical support strategy and might be beneficial for decision-making regarding patient triage, treatment, hospitalization, or patient discharge.