Pancreatic cancer is a complex malignancy associated with poor prognosis and high symptom burden. Optimal patient care relies on the integration of various sectors in the healthcare field as well as innovation through research. The Canadian National Pancreas Conference (NPC) was co-organized and hosted by Craig’s Cause Pancreatic Cancer Society and The Royal College of Physicians and Surgeons in November 2023 in Montreal, Canada. The conference sought to bridge the gap between Canadian healthcare providers and researchers who share the common goal of improving the prognosis, quality of life, and survival for patients with pancreatic cancer. The accredited event featured discussion topics including diagnosis and screening, value-based and palliative care, pancreatic enzyme replacement therapy, cancer-reducing treatment, and an overview of the current management landscape. The present article reviews the NPC sessions and discusses the presented content with respect to the current literature.

Pancreatic cancer (PC) is among the most lethal malignancies with slower progress in overall survival and treatment options compared to other cancers. The 2025 Canadian National Pancreas Conference (NPC)—the third biennial event of its kind—was hosted by Craig’s Cause Pancreatic Cancer Society and the Baker Centre for Pancreatic Cancer in November 2025 in London, Ontario, co-organized by the Canadian Association of General Surgeons (CAGS) with accreditation through the Royal College of Physicians and Surgeons of Canada. The event brought together experts across healthcare disciplines as well as researchers, students, and allied professionals to discuss the latest advances in treatment and management of this complex disease. The conference featured presentations, workshops, and discussions on the current landscape of treatment and management of PC with an emphasis on the increasing significance of genomic sequencing, equitable care, and a multidisciplinary approach.