Landslides are among the most destructive natural hazards in the Western Ghats region of Kerala, driven by complex interactions between geological, hydrological, and anthropogenic factors. This study aims to generate a high-resolution Landslide Susceptibility Level Map (LSLM) using a machine learning (ML)-based Random Forest (RF) model integrated with Geographic Information Systems (GIS). A total of 231 historical landslide locations obtained from the Bhukosh portal were used as reference data. Eight predictive factors—Stream Order, Drainage Density, Slope, Aspect, Geology, Land Use/Land Cover (LULC), Normalized Difference Vegetation Index (NDVI), and Moisture Stress Index (MSI)—were derived from remote sensing and ancillary datasets, preprocessed, and reclassified for model input. The RF model was trained and validated using a 50:50 split of landslide and non-landslide points, with variable importance values derived to weight each predictive factor of the raster layer in ArcGIS. The resulting Landslide Susceptibility Index (LSI) was reclassified into five susceptibility zones: Very Low, Low, Moderate, High, and Very High. Results indicate that approximately 17.82% of the study area falls under high to very high susceptibility, predominantly in the steep, weathered, and high rainfall zones of the Western Ghats. Validation using Area Under the Curve–Receiver Operating Characteristic (AUC-ROC) analysis yielded an accuracy of 0.890, demonstrating excellent model performance. The output LSM provides valuable spatial insights for planners, disaster managers, and policymakers, enabling targeted mitigation strategies and sustainable land-use planning in landslide-prone regions.