Simo Zsuzsa

Ms. Simo Zsuzsa


Research Focus & Metrics

Academic Career Length

4Years (2023-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
5 November 2024 in Applied Sciences
Verified
Journal Article
Open access
PDF file
MMMadalina Maria Muraru
Madalina Maria Muraru
SZSimo Zsuzsa
Simo Zsuzsa
Laszlo Barna IantovicsLaszlo Barna Iantovics
Laszlo Barna Iantovics
Cervical cancer affects a large portion of the female population, making the prediction of this disease using Machine Learning (ML) of utmost importance. ML algorithms can be integrated into complex, intelligent, agent-based systems that can offer decision support to resident medical doctors or even experienced medical doctors. For instance, an experienced medical doctor may diagnose a case but need expert support that related to another medical specialty. Data imbalance is frequent in healthcare data and has a negative influence on predictions made using ML algorithms. Cancer data, in general, and cervical cancer data, in particular, are frequently imbalanced. For this study, we chose a messy, real-life cervical cancer dataset available in the Kaggle repository that includes large amounts of missing and noisy values. To identify the best imbalanced technique for this medical dataset, the performances of eleven important resampling methods are compared, combined with the following state-of-the-art ML models that are frequently applied in predictive healtchare research: K-Nearest Neighbors (KNN) (with k values of 2 and 3), binary Logistic Regression (bLR), and Random Forest (RF). The studied resampling methods include seven undersampling methods and four oversampling methods. For this dataset, the imbalance ratio was 12.73, with a 95% confidence interval ranging from 9.23% to 16.22%. The obtained results show that resampling methods help improve the classification ability of prediction models applied to cervical cancer data. The applied oversampling techniques for handling imbalanced data generally outperformed the undersampling methods. The average balanced accuracy for oversampling was 77.44%, compared to 62.28% for undersampling. When detecting the minority class, oversampling achieved an average score of 60.80%, while undersampling scored 41.36%. The logistic regression classifier had the greatest impact on balanced techniques, while random forest achieved promising performance, even before applying balancing techniques. Initially, KNN2 outperformed KNN3 across all metrics, including balanced accuracy, for which KNN2 achieved 53.57%, compared to 52.71% for KNN3. However, after applying oversampling techniques, KNN3 significantly improved its balanced accuracy to 73.78%, while that of KNN2 increased to 63.89%. Additionally, KNN3 outperformed KNN2 in minority class performance, scoring 55.72% compared to KNN2’s 33.93%.

5 January 2026 in Biomimetics
Verified
Journal Article
Open access
PDF file
RMRidwan Boya Marqas
Ridwan Boya Marqas
SZSimo Zsuzsa
Simo Zsuzsa
Abdulazeez Mousa SulaimanAbdulazeez Mousa Sulaiman
Abdulazeez Mousa Sulaiman
FÖFatih Özyurt
Fatih Özyurt
Laszlo Barna IantovicsLaszlo Barna Iantovics
Laszlo Barna Iantovics
Drug–drug interactions (DDIs) can cause adverse reactions or reduce the efficiency of a drug. Using computers to predict DDIs is now critical in pharmacology, as this reduces risks, improves drug outcomes and lowers healthcare costs. Clinical trials are slow, expensive, and require a lot of effort. The use of artificial intelligence (AI), primarily in the form of machine learning (ML) and its subfield deep learning (DL), has made DDI prediction more accurate and efficient when handling large datasets from biological, chemical, and clinical domains. Many ML and DL approaches are bio-inspired, taking inspiration from natural systems, and are considered part of the broader class of biomimetic methods. This review provides a comprehensive overview of AI-based methods currently used for DDI prediction. These include classical ML algorithms, such as logistic regression (LR) and support vector machines (SVMs); advanced DL models, such as deep neural networks (DNNs) and long short-term memory networks (LSTMs); graph-based models, such as graph convolutional networks (GCNs) and graph attention networks (GATs); and ensemble techniques. The use of knowledge graphs and transformers to capture relations and meaningful data about drugs is also investigated. Additionally, emerging biomimetic approaches offer promising directions for the future in designing AI models that can emulate the complexity of pharmacological interactions. These upgrades include using genetic algorithms with LR and SVM, neuroevaluation (brain-inspired model optimization) to improve DNN and LSTM architectures, ant-colony-inspired path exploration with GCN and GAT, and immune-inspired attention mechanisms in transformer models. This manuscript reviews the typical types of data employed in DDI (pDDI) prediction studies and the evaluation methods employed, discussing the pros and cons of each. There are useful approaches outlined that reveal important points that require further research and suggest ways to improve the accuracy, usability, and understanding of DDI prediction models.

14 September 2024 in Preprints.org
Verified
Preprint
Open access
PDF file
MMMadalina Maria Muraru
Madalina Maria Muraru
SZSimo Zsuzsa
Simo Zsuzsa
Laszlo Barna IantovicsLaszlo Barna Iantovics
Laszlo Barna Iantovics
Cervical Cancer affects a large part of female population that makes the prediction of this disease based on Machine Learning (ML) by outmost importance. ML algorithms can be integrated in complex intelligent agent-based systems that can offer decision support to the resident medical doctors or even to experienced medical doctors. For instance can be mentioned the situation when an experienced medical doctor diagnose a case but he/she needs expertise support that is related to another medical specialty. Data imbalance is frequent in healthcare data and has a negative influencing effect in making predictions using ML algorithms. Cancer data generally and cervical cancer data particularly are frequently imbalanced. Based on this fact the study of data imbalance impact on diverse state-of-the-art ML prediction algorithms is important. This research subject is also motivated by the fact that in many research are presented experimental evaluations of algorithms without characterization of the data on that they have been applied. Such characterizations could give clear indication to other researchers regarding the applicability of the algorithms on their specific data. Specifically, if the data have the respective characteristics than are expectable the same performance evaluation results like those in the reported research. For the study we chosed a messy real-life Cervical Cancer dataset available in a recognized data repository included a large amount of missing and noisy values. To identify the best imbalanced technique for this medical dataset, it is compared the performance of eleven important resampling methods combined with the following state-of-the-art ML models: K-Nearest Neighbours (with k values of 2 and 3), binary Logistic Regression, and Random Forest, that are frequently applied in prediction types of researches in healthcare. The studied resampling methods includes seven undersampling methods namely Condensed Nearest Neighbour, Tomek Links, Edited Nearest Neighbours, Repeated Edited Nearest Neighbours, All K-Nearest Neighbours, NearMiss, Neighbourhood Cleaning Rule, and Instance Hardness Threshold, and four oversampling methods namely Synthetic Minority Oversampling Technique (SMOTE), Adaptive Synthetic Sampling Approach for Imbalanced Learning SMOTE, Support Vector Machine SMOTE and Borderline SMOTE. In the case of the dataset for the confidence interval with 95% confidence level was between 9.23 and 16.22, while the imbalance ratio is 12.73. The obtained results show that resampling methods help the learning models to improve the classification ability of cervical cancer. The applied oversampling techniques generally showed better results than undersampling methods. In the case of Logistic Regression classifier had the highest impact on balanced techniques, while Random Forest had promising performance, even before balancing techniques and KNN2 was generally better than KNN3.

1 December 2023 in Acta Marisiensis. Seria Technologica
Verified
Journal Article
Open access
PDF file
SZSimo Zsuzsa
Simo Zsuzsa
The paper shows the understanding of a topic recognition problem like the speech recognition system based on Natural Language Processing (NLP) and the steps of its implementation of a rules-based approach, which is able to classify given audio materials based on predefined topics in real-time. During implementation, a statistical vocabulary was developed. Google Speech API (Application Programming Interface) was employed for subtitling audio materials, and the most ideal time frame for reception was identified through several experiments. The motivation of this work is based on the deficiency of similar simple systems for Hungarian topic recognition, even though numerous international languages already utilize multiple Automatic Sound Recognition (ASR) systems.

6 September 2023 in Production Systems and Information Engineering
Verified
Journal Article
Open access
PDF file
SZSimo Zsuzsa
Simo Zsuzsa
Laszlo Barna IantovicsLaszlo Barna Iantovics
Laszlo Barna Iantovics
DTDániel Tokody
Dániel Tokody
A behatolás-észlelő rendszer (Intrusion Detection System - IDS) a hálózati forgalmat és a felhasználói tevékenységeket figyeli rosszindulatú adatforgalom felderítéséhez osztott környezetben. Jelen tanulmány néhány előzetes eredményt mutat be, az IDS-ek telepítéséhez javasolt ágens-alapú biztonsági megközelítéssel kapcsolatban. A decentralizált, ágens-alapú IDS feladatokat oszt ki az ágenseknek a fenyegetések felismeréséhez szükséges adatok gyűjtésére, elemzésére és szállítására. Javaslatunk előnyei a következők: nincs egyedi meghibásodási pontja, korlátozza a hálózati terhelést és késést, és megfelelő IDS modellt jelent nagy hálózati környezetek számára. Ilyen például az egészségügyben szereplő páciensek személyes adatainak védelme, amely gépi tanuláson alapuló predikciós algoritmusokkal kombinálva hatékonyabb védelmet biztosíthatnak.