Novel liquid crystal materials base on amino-thiadiazoles, specifically 5-(3,4-di-, and/or 3,4,5-tri-n-alkoxy)phenyl-2-amino-1,3,4-thiadiazoles (3a–f, n = 10, 12, 14) and 5-(3,4-di- and/or 3,4,5-tri-n-alkoxy)phenyl-2-(4-amino)phenyl-1,3,4-thiadiazoles (6a–f, n = 10, 12, 14) were synthesised. The mesomorphic properties of these compounds were studied by differential scanning calorimetry and polarising optical microscopy. All the compounds in series 3a–f and series 6a–f display an enantiotropic columnar phase. The mesomorphic properties were found to be dependent on the number of the side alkoxy chains, and on the length of the rigid core, and on the position of the thiadiazole ring. The best results were obtained with compounds of series 3a–f.

Novel columnar liquid crystals whose molecular structures consist of a C₃ star-shaped 1,3,5-triazine unit as a central core, and three pendant 2-phenyl-5-(di-, and/or tri-n-alkoxyphenyl)-1,3,4-thiadiazole arms, containing ether connecting groups, variable number and positions of linear alkoxy chains were synthesised and their mesomorphic properties were studied by differential scanning calorimetry, polarised optical microscopy and X-ray diffraction. The mesomorphic properties were found to be dependent on the length, position and number of the peripheral alkoxy chains. Most compounds form enantiotropic hexagonal columnar phases. These compounds also show photoluminescent properties in the visible region with good quantum yields. Photophysical studies were realised in solution and in solid state. Also, solvatofluorochromism and cyclic voltammetry studies were performed. Graphical Abstract

Novel liquid crystal materials based on 1,3,5-benzenetrisamide derivatives with three pendant 2-phenyl-5-(mono-, di-, and/or tri-n-alkoxyphenyl)-1,3,4-oxadiazole arms (Ia–c, IIa–c) were prepared. The mesomorphic properties of these compounds were characterised and studied by differential scanning calorimetry, polarising optical microscopy and X-ray diffraction. The formation of a columnar mesophase was found to be dependent on the number of alkoxy side chains. The compounds Ib and IIb, with a total of six alkoxy chains, and compounds Ic and IIc, with nine alkoxy chains, exhibited an enantiotropic hexagonal columnar (Col_h ) phase with high isotropisation temperatures; however, compounds Ia and IIa with a total of three alkoxy chains formed a crystalline phase. Compounds IIb and c were room temperature liquid crystals.

Incorporating nanoparticles into injectable hydrogels is a well-known technique for improving the mechanical properties of these materials. However, significant differences in the mechanical properties of the polymer matrix and the nanoparticles can result in localized stress concentrations at the polymer–nanoparticle interface. This situation can lead to problems such as particle–matrix debonding, void formation, and material failure. This work introduces boronic acid/boronate ester dynamic covalent bonds (DCBs) as energy dissipation sites to mitigate stress concentrations at the polymer–nanoparticle interface. Once boronic acid groups were immobilized on the surface of SiO₂ nanoparticles (SiO₂-BA) and incorporated into an alginate matrix, the nanocomposite hydrogels exhibited enhanced viscoelastic properties. Compared to unmodified SiO₂ nanoparticles, introducing SiO₂ nanoparticles with boronic acid on their surface improved the structural integrity and stability of the hydrogel. In addition, nanoparticle-reinforced hydrogels showed increased stiffness and deformation resistance compared to controls. These properties were dependent on nanoparticle concentration. Injectability tests showed shear-thinning behavior for the modified hydrogels with injection force within clinically acceptable ranges and superior recovery.

Water availability, a vital factor in agriculture, is being threatened by shortages caused by droughts, desertification, and climate change. In this context, hydrogels, polymers with high water absorption and retention capacity, emerge as key solutions to improve water use efficiency in irrigation. This study investigated the effect of a natural superabsorbent hydrogel (TG) at different concentrations (0.3%, 0.5%, 0.8%, and 1.0%) on the water retention capacity in three coarse-textured soils and one medium-textured soil. Results are compared to an existing commercial polymer (COM). The evaluation shows that both polymers increase the values of the water retention curve; however, higher values were observed with TG. The addition of both hydrogels was compared in the increase of the available water capacity (AWC). For sand soil, the TG obtained a statistically significant difference of a 26% greater AWC when compared to the COM superabsorbent. Soils with a higher percentage of sand tend to obtain a greater improvement in the AWC. There is a proportional relationship of the increase in the AWC when increasing hydrogel concentration ($R^2$ = 0.74). Sand soil with a concentration of 0.5% of the TG showed 17.8% of the AWC, while for a concentration of 1.0% of this hydrogel, a value of 35.8% of the AWC was obtained. However, in soils with higher clay content, such as silt loam, the effect was smaller. Finally, the time required to reach a permanent wilting point (PWP) was compared. The loam sand soil increased the time to reach the PWP by more than three times using the TG or COM when compared to the same soil without any hydrogel concentration. In conclusion, the TG significantly improves water retention in coarse and medium-textured soils, making it a promising solution for improving water efficiency in agriculture, especially in drought-affected regions. However, additional field studies are needed to evaluate its long-term durability and environmental compatibility, ensuring its applicability under real agricultural conditions.

Herein, we investigated hydrogels composed of boronic-acid-functionalized alginate and blended with polyvinyl alcohol (PVA) of different molecular weights to control the release of metoclopramide hydrochloride as a function of pH and shear stress. The functionalization of alginate introduced dynamic covalent bonding and pH-responsive properties that can modulate network connectivity. The study investigated the viscoelastic properties of the hydrogels, their drug release profiles, and their responsiveness to changes in pH and shear forces. The results showed that a higher PVA molecular weight and alkaline pH conditions increased hydrogel viscosity and stiffness due to a more stable and interconnected network structure than acidic pH. Metoclopramide release revealed that the hydrogels exhibited pH-responsive drug release behavior. The drug was more readily released under acidic conditions due to the instability of sp²-hybridized boronate ester bonds. The influence of shear forces on the release of metoclopramide was also investigated at shear rates of 1, 10, and 100 s⁻¹, revealing their effect on matrix stiffening. Research shows that AlgBA/PVA hydrogels have unique properties, such as dynamic covalent bonding, that make them sensitive to external mechanical forces. This sensitivity makes them ideal for applications where physiological conditions trigger drug release.