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Dr. Adam Cawley
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24Years (2003-Present)
(Calculated once Scilit publication data is synced: current year − year of first publication + 1)
Representative Publications
View All Publications3 June 2008 in Journal of Mass Spectrometry
Journal Article
ACAdam Cawley
Adam CawleyUFUlrich Flenker
Ulrich Flenker
The administration of synthetic steroid copies is one of the most important issues facing sports. Doping control laboratories accredited by the World Anti‐Doping Agency (WADA) require methods of analysis that allow endogenous steroids to be distinguished from their synthetic analogs in urine. The ability to measure isotope distribution at natural abundance with high accuracy and precision has increased the application of Gas Chromatography–Combustion–Isotope Ratio Mass Spectrometry (GC–C–IRMS) to doping control in recent years. GC–C–IRMS is capable of measuring the carbon isotope ratio (δ13C) of urinary steroids and confirm their synthetic origin based on the abnormal 13C content. This tutorial describes some of the complexities encountered by obtaining valid δ13C measurements from GC–C–IRMS and the need for careful interpretation of all relevant information concerning an individual's metabolism in order to make an informed decision with respect to a doping violation. Copyright © 2008 John Wiley & Sons, Ltd.
1 March 2009 in Steroids
Journal Article
ACAdam Cawley
Adam CawleyGTGraham J. Trout
Graham J. Trout
RKRymantas Kazlauskas
Rymantas Kazlauskas
CHChristopher J. Howe
Christopher J. Howe
AGAdrian V. George
Adrian V. George
1 July 2004 in Forensic Science International
Journal Article
ACAdam Cawley
Adam CawleyEHE.R Hine
E.R Hine
GTG.J Trout
G.J Trout
AGA.V George
A.V George
RKR Kazlauskas
R Kazlauskas
1 June 2009 in Rapid Communications in Mass Spectrometry
Journal Article
MCMichael Collins
Michael CollinsACAdam Cawley
Adam CawleyAHAaron C. Heagney
Aaron C. Heagney
LKLuke Kissane
Luke Kissane
JRJames Robertson
James RobertsonHSHelen Salouros
Helen Salouros
22 October 2010 in Drug Testing and Analysis
Journal Article
ACAdam Cawley
Adam CawleyMCMichael Collins
Michael CollinsRKRymantas Kazlauskas
Rymantas Kazlauskas
DHDavid Handelsman
David HandelsmanRHRobert Heywood
Robert Heywood
AAAndrea Arenas‐Queralt
Andrea Arenas‐Queralt
+1
9 February 2022 in Archives of Toxicology
Journal Article
JKJoshua Klingberg
Joshua KlingbergBKBethany Keen
Bethany KeenACAdam Cawley
Adam CawleyDPDaniel Pasin
Daniel PasinSFShanlin Fu
Shanlin FuThe proliferation of new psychoactive substances (NPS) has necessitated the development and improvement of current practices for the detection and identification of known NPS and newly emerging derivatives. High-resolution mass spectrometry (HRMS) is quickly becoming the industry standard for these analyses due to its ability to be operated in data-independent acquisition (DIA) modes, allowing for the collection of large amounts of data and enabling retrospective data interrogation as new information becomes available. The increasing popularity of HRMS has also prompted the exploration of new ways to screen for NPS, including broad-spectrum wastewater analysis to identify usage trends in the community and metabolomic-based approaches to examine the effects of drugs of abuse on endogenous compounds. In this paper, the novel applications of HRMS techniques to the analysis of NPS is reviewed. In particular, the development of innovative data analysis and interpretation approaches is discussed, including the application of machine learning and molecular networking to toxicological analyses.
About Me
Dr. Adam Cawley is the Scientific Manager of Racing Analytical Services Ltd (RASL) in Melbourne, Australia. In this position, he is responsible for the research, development, validation, accreditation and translation of analytical methods to support the integrity of animal sports, human medico-legal analysis and dietary supplement testing. Adam provides expert opinion for legal matters related to findings of prohibited substances and is a technical assessor for the National Association of Testing Authorities (NATA) in relation to the ISO/IEC 17025 Standard for Chemical Testing. Previously, Adam has held positions as Science Manager at the Australian Racing Forensic Laboratory—a division of Racing NSW, and R&D Manager at the Australian Sports Drug Testing Laboratory—a division of the National Measurement Institute. Adam has co-authored more than 40 peer-reviewed publications in international scientific journals and is currently an Associate Editor for Drug Testing and Analysis. Adam is a Fellow and Chartered Chemist of the Royal Australian Chemical Institute (RACI) and a member of the Association of Official Racing Chemists (AORC). Adam was awarded a Bachelor of Science with First Class Honours (2002) and a PhD in Science (2007) from the University of Sydney.