Solitary fibrous tumor (SFT) is an extremely rare mesenchymal neoplasm usually detected in the pleura, which generally follows a benign course. The localization inside lung parenchyma has more rarely been reported. We present a case of a 51-year-old male with a dry cough, dyspnea, chest pain, and increased perspiration. Radiological images revealed a giant circumscribed mass on the right side of the chest. A transbronchial cryobiopsy of the lung was performed and revealed an SFT. The right upper lobectomy through lateral thoracotomy was performed. The pathological examination confirmed an SFT with a central zone of necrosis that is a sign of malignancy. At a 2-year follow-up, the patient is free of symptoms and with no evidence of recurrence. Although the intrapulmonary localization of an SFT is a rare entity, we should be aware of it as a potential malignant pulmonary neoplasm.

Ectopic parathyroid adenoma is a rare pathology. We present a clinical case of a giant ectopic parathyroid adenoma (PA) in an unusual location, which brought significant diagnostical and therapeutical challenges. The tumour in the mediastinum was found incidentally on chest computed tomography (CT). A biopsy was conducted, and histological examination revealed a well-differentiated neuroendocrine tumour. The tumour was excised via right thoracotomy. The final histological examination revealed a parathyroid adenoma, which was unexpected for our team. After three years of observation, there is no evidence of tumour recurrence.

Spontaneous pneumothorax in pregnancy is a very uncommon condition, with fewer than 100 cases described in the English literature. This case report describes a pregnant woman who experienced two episodes of primary spontaneous pneumothorax during pregnancy. A 31-year-old, Caucasian pregnant woman (P2 G3 A1, gestational age 17+0 weeks), conceived naturally, body mass index 28, a former smoker, arrived at the hospital with dyspnea and chest pain. Pneumothorax was detected and managed with a chest tube. However, three days after discharge, pneumothorax reoccurred. Due to a persistent air leak, video-assisted thoracoscopic surgery was performed. Histological examination revealed enlarged airspaces without any signs of specific lung pathology. Postoperative recovery was uneventful, and the patient delivered a healthy newborn without complications. This case highlights the importance of multidisciplinary, individualized diagnostic and treatment options in pregnant patients with primary spontaneous pneumothorax to prevent misdiagnosis and ensure optimal outcomes for both mother and fetus.