Emanuele Amadio

Dr. Emanuele Amadio


Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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16 October 2024 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
EAEmanuele Amadio
Emanuele Amadio
MMMatteo Mencio
Matteo Mencio
ACAlessandra Carlizza
Alessandra Carlizza
FPFrancescaroberta Panuccio
Francescaroberta Panuccio
GSGiovanni Sellitto
Giovanni Sellitto
Giovanni GaleotoGiovanni Galeoto
Giovanni Galeoto
Background/Objective: Parkinson’s disease (PD), a prevalent neurodegenerative disorder, leads to motor and non-motor impairments, affecting quality of life. Camptocormia can be one of the motor signs of PD, characterized by a severe and abnormal forward flexion of the thoracolumbar spine that typically occurs when walking or standing. The following study aims to verify whether postural gymnastics can be an effective treatment for trunk control, balance, activities of daily living, and general well-being in patients with early-stage PD and camptocormia. Methods: Nine participants (mean age 67.7 ± 7.8) with early PD (Hoehn and Yahr Scale ≤ 2) received 10 biweekly physiotherapy sessions. Outcomes were measured using the Parkinson’s Disease Questionnaire (PDQ-39) and Berg Balance Scale (BBS) along with trunk mobility and muscle tests according to the Medical Research Council (MRC) scale. Results: Statistically significant results were noted in the PDQ-39 mobility, ADLs and emotional well-being subscales and in the BBS; statistically significant improvements were also seen in trunk mobility and muscle strength. Conclusions: This study shows that the postural gymnastic treatment, according to Souchard, in patients with PD’s camptocormia has obtained good results and has the potential timprove mobility and balance, encouraging and motivating patients in their rehabilitation journeys.

10 February 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
EAEmanuele Amadio
Emanuele Amadio
LCLuca Cimini
Luca Cimini
IRIlaria Ruotolo
Ilaria Ruotolo
ACAlessandra Carlizza
Alessandra Carlizza
Anna BerardiAnna Berardi
Anna Berardi
Giovanni GaleotoGiovanni Galeoto
Giovanni Galeoto
Background/Objectives: Due to rigidity, musculoskeletal pain is more common in people with Parkinson’s disease (PD) compared with age-matched older adults, and the shoulder is one of the body parts that is most involved. In the literature, there is no clear standard for the treatment of shoulder pain in people with PD. This clinical trial study aimed to evaluate the effectiveness of physiotherapy treatment for people with PD with painful shoulders. Methods: The main goals were improvements in pain intensity, balance, quality of life (QoL), and activities of daily living (ADL), evaluated with the Parkinson’s Disease Questionnaire 39 (PDQ-39), Berg Balance Scale (BBS), Community Integration Questionnaire (CIQ-R), 12-Item Short-Form Survey (SF-12), Disabilities of the Arm, Shoulder, and Hand (DASH) scale, and Numeric Pain Rating Scale (NPRS). Also, the evaluation comprised range of motion (ROM) evaluation with a goniometer and the Medical Research Council (MRC) scale. The inclusion criteria of this study were a diagnosis of PD associated with shoulder pain, and a stage of disease of 1–2 on the Hoehn and Yahr scale. Results: The sample comprised 16 participants; the mean age of the participants was 72. Through feedback collected from the individuals participating in this study, it emerged that the rehabilitation approach specifically designed for individuals suffering from shoulder pain associated with Parkinson’s disease produced remarkable results. Conclusions: These results were confirmed by a series of statistically significant data, which showed significant improvements in several areas: joint mobility, muscle strength, motor coordination, the ability to perform daily activities, emotional state, pain reduction, QoL improvement, and balance in both dynamic and static conditions.

24 April 2025 in Applied Sciences
Verified
Journal Article
Open access
PDF file
IRIlaria Ruotolo
Ilaria Ruotolo
GSGiovanni Sellitto
Giovanni Sellitto
Giovanni GaleotoGiovanni Galeoto
Giovanni Galeoto
DVDonatella Valente
Donatella Valente
EAEmanuele Amadio
Emanuele Amadio
PFPaola Frati
Paola Frati
Background: Accidents and injuries are major causes of chronic disability, leading to a loss of healthy years. Accurate assessment is essential for planning personalized rehabilitation programs. In recent years, wearable sensors have been introduced into research for motion analysis. This study aimed to validate the Xclinic wearable sensors for ROM assessment in patients with trauma. Methods: Participants were recruited from the Sapienza University of Rome (September 2023–November 2024) after road accident trauma. The active ROM of the hip, knee, and ankle was assessed bilaterally based on the injury. The SF-36 and other specific tools were also administered. Construct validity was tested using Pearson’s correlation coefficient. Results: A total of 44 participants (mean age 42.7 ± 17.3 years, 69% male) were included. Item-by-item analysis revealed significant correlations, with notable findings related to other outcome measures. Conclusions: The correlation between joint restrictions, functional impairment, and psychosocial factors highlights the need to integrate physical and psychological care into rehabilitation. Further research is needed to refine assessment tools to improve patients’ quality of life.

30 April 2026 in Journal of Patient-Reported Outcomes
Verified
Journal Article
Open access
PDF file
GSGiovanni Sellitto
Giovanni Sellitto
ESElisa Simonazzi
Elisa Simonazzi
FPFrancescaroberta Panuccio
Francescaroberta Panuccio
APAndrea Marini Padovani
Andrea Marini Padovani
EAEmanuele Amadio
Emanuele Amadio
IRIlaria Ruotolo
Ilaria Ruotolo
Background: Multiple Sclerosis (MS) significantly affects physical, cognitive, and psychosocial functioning, leading to impaired Health-Related Quality of Life (HRQoL). The EQ-5D-5 L is a widely used generic patient-reported outcome measure (PROM) to assess HRQoL across health conditions. However, its psychometric properties have not been fully established in Italian people with MS (PwMS). This study aimed to evaluate the reliability and validity of the Italian EQ-5D-5 L in PwMS, supporting its applicability in clinical and research contexts. Methodology: A cross-sectional psychometric validation study was conducted in accordance with COSMIN guidelines. Participants were recruited from an Italian tertiary MS center based on the following inclusion criteria: age ≥ 18 years, confirmed MS diagnosis according to the 2017 McDonald criteria, fluency in Italian, and ability to provide informed consent and independently complete the questionnaire. Eligible participants completed the Italian EQ-5D-5 L and the MSQOL-54 in person. Test-retest reliability was assessed via Intraclass Correlation Coefficients (ICC) after a 48-hour interval in clinically stable participants, construct validity through Pearson’s correlations with MSQOL-54 domains, and known-groups validity by ANOVA and t-tests across disability levels (EDSS), employment status, and physiotherapy engagement. Results: Sixty-nine PwMS (55% female; mean age 49 ± 13 years) were included. The EQ-5D-5 L showed high test–retest reliability (ICC range = 0.81–0.95). Strong correlations supported construct validity, particularly between the EQ-Index and the Physical Health Composite Score ( r = 0.76, p < 0.001) and between the EQ-VAS and the Overall Quality of Life item ( r = 0.71, p < 0.001). Known-groups validity was confirmed, with higher HRQoL scores among participants with mild disability (EDSS 0–3.5) and those employed (both p < 0.001). Conclusions: The Italian EQ-5D-5 L showed satisfactory reliability and construct validity in PwMS, supporting its use as a generic measure of HRQoL in clinical and research settings. The relatively small sample size, particularly in the test–retest subgroup, should be considered when interpreting these findings. Additional measurement properties, including content validity, were not specifically evaluated in the present study. Complementary use with MS-specific instruments remains advisable to capture domains such as fatigue and cognitive function.

21 February 2025 in Sensors
Verified
Journal Article
Open access
PDF file
Giovanni GaleotoGiovanni Galeoto
Giovanni Galeoto
IRIlaria Ruotolo
Ilaria Ruotolo
GSGiovanni Sellitto
Giovanni Sellitto
EAEmanuele Amadio
Emanuele Amadio
ESEnrica Di Sipio
Enrica Di Sipio
PFPaola Frati
Paola Frati
Background: Kinematics experts and physical therapists have implemented the use of sensors for 3D motion analysis, both for static and dynamic movements. XClinic movement sensors are advanced devices designed to analyze movement patterns with high precision. The aim of this study was to validate wearable XClinic sensors for range of motion (ROM) in healthy subjects and obtain normative data. Participants were enrolled at the Sapienza University of Rome in 2024. All participants had to be healthy subjects aged between 18 and 65 years. Data on their demographics, employment and physical activity were collected. All the subjects were tested to assess the active ROM of their shoulder, hip, knee and ankle bilaterally. The same movements were tested using a goniometer to investigate validity, and SF-36 was administered. Fifty subjects were enrolled. The mean age was 28.2 (SD 10.8) years. For the left shoulder, construct validity showed statistically significant values for flexion, extension and extra-rotation, while for the right shoulder, construct validity showed statistically significant values for all movements except intra-rotation. The results concerning the right hip showed statistically significant values for flexion, extra-rotation, intra-rotation and adduction. The left hip showed statistically significant values for all movements except extension. Both the right and left knees showed statistically significant values for flexion. Both the right and left ankles showed statistically significant values for all movements. XClinic sensors offer a reliable and valid solution for the precise monitoring of the ROM of the shoulder and lower limb joints, making them an invaluable asset for clinicians and researchers.

28 October 2026 in BMC Sports Science, Medicine and Rehabilitation
Verified
Journal Article
Open access
PDF file
GSGiovanni Sellitto
Giovanni Sellitto
FPFederica Pasquali
Federica Pasquali
IRIlaria Ruotolo
Ilaria Ruotolo
GGGloria Giglioni
Gloria Giglioni
EAEmanuele Amadio
Emanuele Amadio
Giovanni GaleotoGiovanni Galeoto
Giovanni Galeoto
Injury surveillance in athletics often depends on athletes reporting injuries, whereas weekly instruments developed at the Oslo Sports Trauma Research Cent