This article aims to study the etiological and clinical profile of acute heart failure in Angola and to identify the predictors associated with in-hospital mortality. Methods: A descriptive, observational, cross-sectional study was carried out in a tertiary public hospital in Angola. Information on demographic and biological data was collected. The following variables were included: demographic, etiological, and clinical characteristics, cardiovascular risk factors, precipitating factors of cardiac decompensation, comorbidities, and complications. In the univariate analysis we evaluated absolute and relative frequency, in the bivariate analysis independent Mann-Whitney Test, T Student test, and Chi-Square, tests were used as appropriate. Results: The sample comprises 257 individuals, of which 114 (44.36%) are male. The mean age is 49.90 ± 15.95 years. Hospital mortality is 23%. Predictors of poor prognosis were male sex (56.67% vs 40.61%, p = 0.037), lower systolic, diastolic, and mean blood pressure ((mean = 115 mmHg vs 138 mmHg, p < 0.001; mean = 73 mmHg vs. 85 mmHg, p < 0.001 and mean = 87.55 mmHg vs 102.74 mmHg; p < 0.001, respectively), higher respiratory rate (mean = 26.48 vs 24.00, p = 0.013), New York Health Association (NYHA) Class IV (60.00% vs 35.03%, p < 0.001) and lower LVEF (mean = 34.90% vs 39.7%, p = 0.013) Infection as a precipitating cause of cardiac decompensation, a previous history of pulmonary TB and DCM were also associated with higher in-hospital mortality (61.66% vs 26.39%, p < 0.001; 33.33% vs 12.69 p < 0.001, and 45.00% vs 29.95%, p = 0.031; respectively). Conclusions: The results indicate that in Angola, heart failure affects young and middle-aged patients and is associated with high in-hospital mortality. 本文旨在研究安哥拉急性心力衰竭的病因和临床特征,并确定与院内死亡率相关的预测因素。方法:在安哥拉的一家三级公立医院开展了一项描述性、观察性、横断面研究。收集了有关人口统计和生物数据的信息。包括以下变量:人口统计学、病因学和临床特征、心血管危险因素、心脏代偿失调的诱发因素、合并症和并发症。 在单变量分析中,我们评估了绝对和相对频率,在双变量分析中,我们酌情使用了独立的 Mann-Whitney 检验、T Student 检验和卡方检验。 结果:样本共257人,其中男性114人(44.36%)。平均年龄为 49.90±15.95岁。住院死亡率为23%。 预后不良的预测因素是男性(56.67% vs 40.61%,p = 0.037)、较低的收缩压、舒张压和平均血压((平均值= 115 mmHg vs 138 mmHg,p<0.001;平均值= 73 mmHg vs 85 mmHg , p<0.001 和平均值= 87.55 mmHg vs 102.74 mmHg;分别为 p<0.001),更高的呼吸频率(平均值= 26.48 vs 24.00,p=0.013),NYHA IV级(60.00% vs 35.03%,p<.001) 和较低的LVEF(平均值= 34.90% vs 39.7%,p=.013) 感染是心脏代偿失调的诱发因素,既往肺结核病史和 DCM 也与较高的院内死亡率相关(分别为61.66% vs 26.39%,p <.001;33.33% vs 12.69 p<.001,以及 45.00% vs 29.95%,p=.031;)。结论:结果表明,在安哥拉,心力衰竭影响年轻和中年患者,并与住院高死亡率相关。