The medial patellofemoral ligament (MPFL) is critical for patellar stability. This study investigates the efficacy of a one-year physical therapy rehabilitation program following MPFL reconstruction using Synthetic Graft (SG) and Quadriceps Tendon Autograft (QTA). Thirty-five patients aged 18–38 underwent MPFL reconstruction (20 SG, 15 QTA). They participated in a structured rehabilitation program to improve their range of motion (ROM), muscle strength, pain management, and overall quality of life (QoL). The program included physiotherapy and MLS laser, Game Ready Therapy, EMS, TENS, TECAR, and lymphatic drainage. Before and after the program, assessments included knee flexion and extension using goniometry, muscle strength via the Medical Research Council (MRC) scale, knee circumference, pain intensity on the Visual Analogue Scale (VAS), and QoL with the EQ-5D instrument. Significant improvements were observed in knee flexion (37.57° vs. 114.71°, p < 0.001), muscle strength (MRC scale 1–4 points vs. 4–5 points, p < 0.001), and pain reduction (VAS 6.66 vs. 0.46, p < 0.001). The functional coefficient of mobility and QoL scores also markedly increased. Patients with QTA improved some parameters better than those with SG. These findings support the effectiveness of a comprehensive rehabilitation program in enhancing knee functionality, reducing pain, and improving QoL post-MPFL reconstruction. Personalized rehabilitation protocols are recommended to optimize recovery outcomes.

Background/Objectives: Physical activity (PA) is a key determinant of mental and physical health, yet its relationship with affective states remains insufficiently explored. Emotional factors, such as depression, anxiety, and motivation levels, can significantly impact PA engagement. This study aims to validate the Affective State and Physical Activity Questionnaire (ASPAQ), a novel 15-item instrument designed to assess the interplay between affective states and PA in adults. Methods: A cross-sectional study was conducted with 412 adults (145 males, 267 females, aged 18–65 years). Participants completed the ASPAQ alongside the International Physical Activity Questionnaire—Short Form (IPAQ-SF) and the Patient Health Questionnaire-9 (PHQ-9) on an online platform, with the support of trained operators. The psychometric properties of the ASPAQ were evaluated using reliability tests (Cronbach’s alpha, McDonald’s omega), exploratory factor analysis (EFA), and correlational analyses to assess convergent validity. Results: The ASPAQ demonstrated excellent reliability (Cronbach’s alpha = 0.973; McDonald’s omega = 0.973) and a unidimensional structure. Convergent validity was supported by significant correlations between ASPAQ scores and established measures of PA (IPAQ-SF) and depression (PHQ-9). EFA confirmed a single-factor model, reinforcing its conceptual integrity. Conclusions: The ASPAQ is a reliable and valid instrument for assessing the relationship between affective states and PA. Its integration with established measures offers a comprehensive tool for evaluating emotional barriers to PA. Future studies should explore its predictive validity and potential applications in clinical and public health settings to inform personalized interventions promoting PA among individuals with affective challenges.