Brain microcirculation is the intricate network of blood vessels encompassing arterioles, capillaries, and venules that delivers oxygen and nutrition and removes waste products necessary for the proper functioning of brain tissue.1,2 It plays a critical role in maintaining homeostasis associated with metabolic requirements and oxygen distribution to the tissue in the brain. In particular, brain capillaries play a pivotal role in facilitating the exchange of essential nutrients and oxygen to support neurons. However, in the presence of neurological disorders, such as Alzheimer’s disease3 or stroke,4–6 this microcirculatory system can be disrupted due to capillary stalling.