Background: Tuberculosis is a major public health concern in Yemen. Recurrence of tuberculosis complicates the situation further, and has severe negative economic and health consequences. This study estimated the tuberculosis recurrence rate during a 5-year follow-up period, and identified risk factors associated with recurrence. Methods: This was a prospective study with a 5-year follow-up period conducted at health centres with tuberculosis units in ten governorates. Participants were prospectively enrolled in the study from July 2007 to June 2008, with the last patient completing treatment on March 15, 2009. Results: A cohort of 814 patients with pulmonary tuberculosis completed treatment and was followed-up for five years. During the follow-up, 3.4% (n = 28) died and 4.3% (n = 35) were lost to the study, giving a final cohort of 751 patients. The mean age ± standard deviation was 32 ± 13 years. Males represented 57.6% of the subjects. The overall recurrence rate of tuberculosis was 9.5% (71/751), with significant variation between subgroups of patients (range = 7–25.8%). The highest recurrence rates were found in patients with diabetes (25.8%, p < .001), non-adherent patients (22%, p < .001), smokers (16.1%, p = .010), patients with cavitary lung disease (14.4%, p = .004), patients with weight gain ≤5% during the intensive phase (13.3%, p < .001) and unemployed patients (11.9%, p = .017). In multivariate logistic regression analysis, these risk factors were independently associated with recurrent tuberculosis: diabetes (adjusted odds ratio, aOR 3.78, 95% confidence interval, CI 1.84–7.80), non-adherence (aOR 3.22, 95% CI 1.76–5.87), weight gain ≤5% (aOR 2.51, 95% CI 1.39–4.55), smoking (aOR 2.18, 95% CI 1.07–4.47), presence of lung cavitation (aOR 2.01, 95% CI 1.16–3.46), and unemployment (aOR 2.15, 95% CI 1.16–4.01). Conclusion: The recurrence rate of tuberculosis in Yemen was high. The presence of risk factors in newly diagnosed patients should alert healthcare professionals. As most of risk factors were modifiable, the World Health Organisation model of patient-centered care in tuberculosis treatment should be promoted in all tuberculosis centres in the country.

Background: Social media (SM) use has become an integral aspect of daily life. Overutilization of SM can adversely impact an individual’s physical and emotional well-being, especially that of students. This study evaluated the potential impact of SM addiction on anxiety and academic performance among university students. Methods: A cross-sectional study was conducted among medical ad non-medical students at Qassim University during September 2022–April 2023 after obtaining the Ethics Committee’s permission. Raosoft was used for calculating the sample size, and participants were selected through convenience sampling. Both descriptive and inferential statistics were used to analyze and interpret the results, using SPSS version 25. Results: A total of 269 students participated in the study. The majority of them were male (52%), with a mean age of 22.28. The main purpose of SM usage was entertainment, followed by communication. More than 30% of them were using SM for 4–6 h per day, accessing SM 1–10 times in a day, with more than half of them feeling that they had SM addiction and that it was affecting their daily activities and sleep. The majority of them agreed that SM can be used for group discussion (78.1% vs. 71.6%) and knowledge sharing (93.7% vs. 90%). However, a statistically significant difference was observed about anxiety level between the two groups. A negative correlation was found between cumulative grade point average (CGPA) and anxiety level. Conclusion: The findings suggest that SM has both positive and negative effects on academic performance and social anxiety. Continuous education and motivation about wise use of SM is warranted among students by parents, university authorities, and policymakers.

Appropriate drug information is vital for the correct use of drugs in pharmaceutical practice. Providing patients with educational advice on prescribed medication and on proper medication administration has become an essential part of the pharmaceutical care process. The objectives of this study were to identify patients’ knowledge of prescribed medications, their desire for more information, and the sources of medication information in a population from Qassim, Saudi Arabia, using a cross-sectional descriptive study. Our target population consisted of adult patients with chronic illnesses receiving drugs at outpatient pharmacies. Nineteen pharmacies were selected based on convenience. After collecting their prescriptions, patients were asked to take part in the study by interviewers as they were leaving the pharmacies. The questionnaire used was pretested on 18 patients and then modified accordingly. questions investigated participants’ knowledge of drug information, their wish for more information, and their sources of drug information, other than clinicians. Descriptive analysis was used to describe patients’ physical details. The effect of sex, education, diagnosis, number of drugs, and age on knowledge of the purpose of drugs and the need for additional information were tested using Chi-square test. A total of 270 patients were interviewed, of whom 29.7% reported not knowing the purpose of at least one of their medications, and only reading a portion of the PILs. Of the patients sampled, 56.7% said they read the side effects section of the PIL, 43.3% reported reading the uses, while 27% read the contraindications. The drug -interactions section was the least read, with only 18.9% reporting reading it. A total of 57% of the patients reported that they needed more information about their medications. Highly educated patients reported using the PIL, social media, family and friends, TV, and newspapers as sources of drug information at significantly higher rates than patients with lower levels of education. Healthcare professionals should assess patient comprehension and the need for additional drug information, especially among patients with low levels of education. Additionally, healthcare professionals should consider other information sources used by their patients.

Background: Oral isotretinoin is an effective treatment for refractory and moderate acne unresponsive to conventional therapies, considered the most effective option for such cases. Objective: This study aimed to evaluate the knowledge, concerns, and experiences of acne patients undergoing isotretinoin treatment in Qassim, Saudi Arabia, with a focus on commonly reported adverse effects. Methods: A cross-sectional study was conducted from December 2023 to February 2024 using a self-administered questionnaire. This study targeted male and female acne vulgaris patients from the Qassim region attending the outpatient dermatology clinic at King Saud Hospital (KSH). Results: A total of 131 acne patients participated. Of these, 97.7% had heard of isotretinoin, and 92.4% were aware of its side effects. The most common sources of information were colleagues, friends, or family (37.4%), followed by previous use (26%) and healthcare professionals (24%). The most frequently reported side effect was dryness (51.9%), followed by liver function changes (24.4%) and fetal abnormalities (13%). There was a significant association between educational level and knowledge of isotretinoin’s side effects (p = 0.003) and awareness of specific side effects (p < 0.001). Conclusion: Most acne patients had sufficient knowledge of isotretinoin and its adverse effects, with dryness being the most commonly reported side effect. The primary sources of information were non-medical, highlighting the need for health education to ensure informed and safe isotretinoin use.

Objective: The study aimed to evaluate the knowledge and counseling skills of community pharmacy professionals regarding managing acute diarrhea in children in the Qassim region of Saudi Arabia. Methods: A cross-sectional study consisting of a questionnaire and simulated client scenario was conducted to collect data from pharmacy professionals working in community pharmacies over a period of 3 months in the Qassim region of Saudi Arabia. Pharmacy professionals were assessed for evaluating cases using 5 indicators (the age of the child, the frequency of diarrhea, fever and the presence of mucus or blood) and also for their recommendations and counseling. Results: The data were collected from 60 pharmacy professionals after site visits. In the questionnaire, 60% of the pharmacy professionals used all 5 indicators, while in the simulation, 13.3% used at least 3 indicators and 80% used 2 or fewer indicators (p = 0.35). An oral rehydration solution was recommended alone by 35% of the pharmacy professionals and with other drugs by 13.3% in the questionnaire, while in the simulation, an oral rehydration solution alone was recommended by 15% and other drugs by 48.3%. Approximately 86.7% of the pharmacy professionals did not give any dietary advice, and 50% did not counsel the simulated client on the recommended drug. Conclusion: The community pharmacy professionals in the study did not ask enough questions to evaluate a child suffering from acute diarrhea appropriately in the simulation. More questions were asked in the questionnaire; however, the difference is not significant. Additionally, they did not provide proper dietary advice, and their recommendation of an oral rehydration solution was insufficient.

Irritable bowel syndrome (IBS) is a prevalent chronic gastrointestinal disorder affecting nearly 20% of the global population, with symptoms including constipation, diarrhea, bloating, and abdominal pain. As frontline healthcare providers, community pharmacists play a pivotal role in IBS management through medication guidance and patient education. However, their understanding, perceptions, and practices regarding IBS remain understudied in many regions, including Saudi Arabia. This study aimed to evaluate community pharmacists’ preparedness for IBS management by assessing their awareness, perceptions, and clinical support practices in the Qassim region of Saudi Arabia. A descriptive, cross-sectional study was conducted among community pharmacists in Qassim (May–August 2024) using a self-administered, 35-item questionnaire. The validated instrument assessed demographics, IBS awareness, perceptions, and clinical practices via closed-ended questions. Descriptive statistics were expressed as frequencies and percentages. Inferential analysis was performed using the Mann–Whitney U test for 2-group comparisons and the Kruskal–Wallis H test for comparisons involving 3 or more groups, with statistical significance set at P < .05. Of the 67 participants, 62.7% were male. The median age among all participants was 34 years (interquartile range = 32–38). While 61.2% of the participants demonstrated adequate IBS awareness, 38.8% had significant gaps. Notably, 77.6% recognized IBS as a quality-of-life-impairing condition, whereas 22.4% underestimated its clinical significance. Perceptions were largely constructive (64.2%), although 35.8% held negative views. Strikingly, 74.6% correctly identified IBS as more common than colorectal cancer, highlighting awareness of its prevalence. Awareness was significantly associated with higher education level ( P = .041) but not with years of experience, sex, or nationality. In total, 52.65% of the pharmacists demonstrated adequate clinical preparedness for IBS management. While the majority of Qassim community pharmacists possess foundational competence for IBS counseling, the study reveals critical gaps in recognizing warning signs and applying evidence-based pharmacotherapy. These findings underscore the necessity of targeted educational interventions and continuing professional development programs to enhance pharmacists’ preparedness.