Periodontal and peri-implant soft and hard tissue in diabetic patients have always been a topic of interest for researchers and clinicians alike. Among which, a subtopic that has attracted more attention is the beneficial effect of metformin (MF) on periodontal and peri-implant soft and hard tissue. This review aimed to assess the impact of MF on the periodontal and peri-implant soft- and hard-tissue healing among diabetic patients. Research was conducted using the keywords ‘metformin’, ‘diabetes’, ‘periodontitis’, ‘implant’, and ‘peri-implantitis’ via the Medline (PubMed) and Google Scholar databases. Selected articles were reviewed. A total of 21 articles, discussing the impact on periodontal health (six animal studies, seven clinical studies, and three systematic reviews) and five studies on peri-implant health (four animal studies and one clinical study) were included. All have reported a positive impact of MF on decreasing the inflammatory response, oxidative stress, and ultimate bone loss. Similarly, human studies reported a positive effect of MF on clinical and radiographic parameters compared with controls. Despite systematic reviews reporting heterogeneity among the included studies, MF has shown a positive impact on periodontal health. In animal, clinical studies, and systematic reviews, MF showed a protective impact on periodontal and peri-implant health.

Background/Objectives: Gingival recession (GR), characterized by the apical displacement of the gingival margin leading to root exposure, risk of root caries, dentine hypersensitivity (DH), and plaque accumulation. This study aimed to evaluate the awareness, causes, and consequences of gingival recession among adults in Saudi Arabia. Methods: A cross-sectional self-reported survey was conducted from September 2023 to December 2024, involving 619 participants (51.53% male). Participants were recruited through dental clinics, community centers, and online platforms across multiple regions in Saudi Arabia to ensure diverse demographic and socioeconomic representation. A validated 27-question survey collected data on demographics, oral hygiene practices, and GR awareness and related factors. Statistical analysis was performed using SAS 9.4, with significance set at p < 0.05. Results: The prevalence of GR was 26.66%, dental plaque was the most frequently reported causing factor, followed by medical conditions (45.4%). Aesthetic concerns were the most recognized consequence (78.4%) followed by periodontitis and tooth mobility and tooth loss (58.5%). Medical disease (Odds Ratio OR = 2.149, p < 0.0001), trauma (OR = 1.515, p = 0.0078), and rough brushing (OR = 1.431, p = 0.0233) were identified as significant risk factors for gingival recession. The association between gingival recession (GR) and its perceived consequences was generally not statistically significant. However, a significant relationship was observed with dental caries (p = 0.0472). Conclusions: Gingival recession awareness among Saudi adults was influenced by age, gender, smoking, and oral hygiene factors. The findings emphasize the importance of raising awareness and promoting preventive strategies targeting modifiable risk factors to reduce GR prevalence and clinical impact.

Introduction and aim Periodontal disease, initiated by dental biofilm and influenced by various local and systemic factors, includes stress as a potential contributor to its progression. Despite associations with severe forms like acute necrotizing ulcerative gingivitis, a comprehensive large-sample study linking stress to periodontal disease is lacking. This study aims to investigate the relationship between mental health and periodontal disease. Materials and Methods Leveraging data (secondary dataset) from the National Health and Nutrition Examination Survey (NHANES) from 2011–2012 and NHANES 2013–2014 cycles, relevant information was extracted. Mental health was the exposure variable, and periodontal disease, assessed through indices following Eke et al.’s definition, served as the outcome. Covariates (demographical characteristics) impacting periodontal disease were considered, and disease status analyses employed the Rao-Scott chi-squared test. A logistic regression model assessed mental health’s impact on periodontal disease. Results Among the 2764 Participants, more than a quarter (29.1%) were aged over 60 years, 52% were females. Logistic regression indicated higher odds of periodontal disease among individuals feeling bad about themselves for more than half of the day (OR 1.170, 95% CI 0.533-2.474), though statistical significance was not reached. Periodontitis prevalence significantly varied based on marital status, with 6.6% of married and 10.8% of unmarried Participants affected. Notably, a statistically significant difference in periodontitis prevalence existed between Participants with health insurance (8.3%) and those without (16.5%). Conclusion Our findings suggest trends in periodontal disease prevalence linked to mental health, marital status, and access to health insurance. However, the absence of statistically significant findings calls for caution in interpreting these relationships. We recommend that future studies further investigate these potential associations to provide a clearer understanding.

Purpose: This study aimed to examine the association between the use of marijuana, hashish, cocaine, methamphetamine, and heroin with the severity of periodontal disease in adults. Patients and Methods: Data were obtained from the National Health and Nutrition Examination Survey (NHANES) 2011– 2012 and 2013– 2014 cycles, from 3609 participants, including demographic information, clinical examinations, and questionnaires. Key covariates assessed in the analysis included age, sex, race/ethnicity, education level, socioeconomic status, poverty/income ratio, marital status, occupation, alcohol consumption, body mass index (BMI), dental insurance coverage, and frequency of dental visits. Logistic regression models were employed to investigate the association between drug use and periodontitis, adjusting for potential confounders. Results: Among 3690 participants, 54% reported using marijuana or hashish, while 16% had tried cocaine, heroin, or methamphetamine. Marijuana or hashish use was significantly associated with severe periodontitis, affecting 39% of users (OR: 4.276; 95% CI: 3.682– 4.967; p = 0.001). Cocaine use was also linked to increased periodontitis, with most users presenting with mild disease. Alcohol consumption was positively associated with periodontitis (OR: 1.255; 95% CI: 1.066– 1.477; p = 0.006). No significant associations were found for heroin or methamphetamine use. Conclusion: Within the limitations of this study, marijuana, hashish, and cocaine users were found to have significantly higher odds of developing periodontitis. However, no clear relationship was established between the use of methamphetamine or heroin and periodontal disease. These findings suggest the need for public health interventions targeting substance users to mitigate the risk of periodontal disease.

Introduction: Periodontal disease is a prevalent inflammatory condition influenced by various risk factors, including tobacco use. With the rising popularity of electronic cigarettes (e-cigarettes), their potential impact on periodontal health warrants investigation. The aim was to assess the...