The mature larva and pupa of Conotrachelus dimidiatus Champion, 1904 (Curculionidae: Molytinae) are morphologically re-described, keyed and, for the first time, compared with known larvae and pupae of other Conotrachelus species. The chaetotaxy of the larval and pupal body in the genus Conotrachelus is probably strictly uniform. The immature stages of described species are also compared with available data on the immature stages of genera from several tribes in the subfamily Molytinae. All larvae of Conotrachelus have a distinct endocranial line of a different size and a frons with only three setae. The states of these two distinct characteristics in larvae of the eight known Conotrachelus species are constant and unique compared to other tribes in the subfamily Molytinae. In Central Mexico, overwintering Conotrachelus beetles emerge in July and then feed and mate on host plants. Larvae are endophagous within the fruits. In September and October, the larvae pupate in the soil. This new information will be very useful in the application of pesticides to the fight against this well-known pest in Mexico.

Background: Dysmenorrhea and premenstrual syndrome (PMS) are common disorders in the Mexican population, but these are usually underdiagnosed and under-treated, impacting women’s quality of life. Adequate health habits have been reported as precursors of decreasing dysmenorrhea symptoms. However, few studies assess their impact on PMS. Aim: This study aims to evaluate dysmenorrhea and premenstrual syndrome in association with health habits in the Mexican population. Methods: To assess the impact of health habits on menstruation symptoms a validated survey was conducted in 1679 adult females aged ≥18 years. The survey collected data on participants’ dysmenorrhea, PMS, and their health habits. Results: The analysis showed that physical activity duration, changes in eating habits (increases in salty or sugary foods) during menstruation, and oversleeping habits predict increases in dysmenorrhea and PMS. In contrast, an active sexual life, relaxing physical activity, and adequate sleep hours during menstruation seem to decrease the symptoms. Conclusions: We conclude that adequate health habits and addressing early gynecological conditions might regulate dysmenorrhea and PMS.

Repurposing of approved drugs allows strong savings in time and investment. Rimantadine is an FDA-approved drug for prevention and treatment of influenza A infection. Patent US2021330605 describes ...

Benzo(a)pyrene (BaP) is a highly distributed molecule in ecosystems and a component of products that are used and consumed regularly. Recent studies have shown this xenobiotic metabolized by organisms forming carcinogenic metabolites, as well as having genotoxic and teratogenic ef fects associated with infertility and endocrine disorders. Similarly, due to its dispersion and bioaccumulation, this molecule can severely damage various ecosystems. Therefore, the objective of this study is to conduct a systematic review to demonstrate the importance of BaP in biological systems and its biodegradation as an alternative to bioremediation.

RESUMEN El bisfenol A (BPA por sus siglas en inglés), un compuesto orgánico fenólico, fue sintetizado por primera vez en Alemania hace más de un siglo. Su auge industrial comenzó a mediados del siglo XX, en donde ¡nidalmente se combinaba con diferentes químicos para la producción de plásticos y resinas. Durante las últimas décadas, se ha reportado ampliamente sus efectos nocivos. En las salud humana, se han comprobado sus efectos genotóxicos, neurotóxicos, así como su efecto como disruptor endocrino. Adicionalmente, el BPA es un compuesto recalcitrante, encontrándose en agua, suelo y atmósfera en concentraciones perjudiciales para la fauna y flora residente de los sitios afectados, causando efectos irreversibles. El ecosistema acuático es particularmente vulnerable a la toxicidad por BPA. Este compuesto entra en los cuerpos de agua a través de los efluentes de plantas de tratamiento de aguas residuales y vertederos. Por lo anterior, es necesario desarrollar sistemas eficientes para la recuperación de los sistemas acuáticos afectados por BPA. Dentro de las herramientas más eficientes como alternativas para el tratamiento del BPA, se encuentra la bioremediación, debido al papel principal que cumplen los microorganismos para la transformación, degradación y eliminación del BPA. Así, en este artículo se presenta una pequeña revisión sobre los alcances y logros de la bioremediación del BPA, con énfasis en ambientes acuáticos. ABSTRACT The Bisphenol A (BPA), a phenolic organic compound, was synthetized more than a century ago, for the first time in Germany. BPA industrial boom began in the middle of the 20^th century, where it was combined with different Chemicals for the production of resins and plástic. Over the last decades, harmful effects of BPA have been widely reported. On human health, it has been shown to have genotoxic and neurotoxic effects, as well as effects as an endocrine disruptor. In addition, BPA it is a recalcitrant compound, it is found in soils, water and in the atmosphere in harmful concentrations for the fauna and flora that inhabits the affected sites. The aquatic ecosystem is of particular vulnerability to BPA toxicity. BPA enters to water bodies through effluents from wastewater treatment plants and landfills. For these reasons, it is necessary to develop efficient systems for the recovery of the affected aquatic ecosystems by BPA. Among the most efficient tools as alternatives for BPA treatment, it is found the bioremediation, this is due to the mail role that microorganisms play for BPA transformation, degradation and elimination. Thus, this paper present an overview about the progress and achievements of BPA bioremediation with focus on aquatic environments.

The environmental and health concerns associated with the widespread use of synthetic pesticides have intensified the search for sustainable alternatives to control phytopathogenic fungi. In this context, members of the Burkholderia sensu lato group have been recognized for their ability to produce diverse bioactive metabolites with antifungal properties. In this study, the antifungal activity of 36 rhizosphere-derived strains was evaluated against Hemileia vastatrix , Fusarium solani , Fusarium oxysporum , and Alternaria longissima . Approximately 80% of the strains inhibited the uredospore germination of H. vastatrix , while 37%, 50%, and 45% reduced radial growth of F. solani , F. oxysporum , and A. longissima , respectively. Selected strains (GB99, D335, and D416) produced heat-stable metabolites that retained activity across a wide pH range and showed partial resistance to hydrolytic enzymes. Metabolomic profiling by high-performance liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (HPLC-ESI-QTOF-MS), performed on metabolites produced by strain GB99, revealed multiple putative antifungal compounds, including burkholdine, occidiofungin and lagriamide related metabolites. Molecular docking, used as an exploratory approach, suggested potential interactions with multiple fungal protein targets. Overall, these findings highlight the chemical diversity and antifungal potential of Burkholderia sensu lato metabolites as promising candidates for sustainable biocontrol strategies.