Malaria and coronavirus disease-2019 (COVID-19) may have similar aspects and seem to have a strong potential for mutual influence. They have already caused millions of deaths, and regions where malaria is endemic are at risk of further suffering from the consequences of COVID-19 due to mutual side effects, like less access to treatment due to fear of access to health facilities leading to diagnostic delays and worse outcomes. A narrative literature review was conducted by searching online databases like Pub Med, Cochran, Medline, Google scholar, malarial journals, health journals, MDPI and biomed central related journals, 133 articles published from 2004 to 2024 were analysed and discussed. The Management of malaria during the COVID-19 pandemic in Uganda required a comprehensive approach that balances the need for both malaria and COVID-19 control, prevention and treatment. These include: Integration of services, healthcare infrastructure strengthening, expanded testing, treatment access, community education and awareness, health worker training, testing and surveillance, mobile health solutions, community engagement, research and innovation, adaptive management, cross-sector collaboration, international cooperation, vector control, monitoring and evaluation. In this chapter, we provide a comprehensive review of integrated management approaches for malaria and covid-19 management in Uganda. In implementing this comprehensive approaches, we can effectively manage both malaria and COVID-19, reduce the burden of disease, and protect the health and well-being of communities in Uganda and worldwide.