As members of an increasingly aging society, one of our major priorities is to develop tools to detect the earliest stage of age-related disorders such as Alzheimer's Disease (AD). The goal of this paper is to evaluate the possibility of using unobtrusively collected activity-aware smart home behavior data to detect the multimodal symptoms that are often found to be impaired in AD. After gathering longitudinal smart home data for 29 older adults over an average duration of >2 years, we automatically labeled the data with corresponding activity classes and extracted time-series statistics containing ten behavioral features. Mobility, cognition, and mood were evaluated every six months. Using these data, we created regression models to predict symptoms as measured by the tests and a feature selection analysis was performed. Classification models were built to detect reliable absolute changes in the scores predicting symptoms and SmoteBOOST and wRACOG algorithms were used to overcome class imbalance where needed. Results show that all mobility, cognition, and depression symptoms can be predicted from activity-aware smart home data. Similarly, these data can be effectively used to predict reliable changes in mobility and memory skills. Results also suggest that not all behavioral features contribute equally to the prediction of every symptom. Future work therefore can improve model sensitivity by including additional longitudinal data and by further improving strategies to extract relevant features and address class imbalance. The results presented herein contribute toward the development of an early change detection system based on smart home technology.

To date, the use of synthetic data generation techniques in the health and wellbeing domain has been mainly limited to research activities. Although several open source and commercial packages have been released, they have been oriented to generating synthetic data as a standalone data preparation process and not integrated into a broader analysis or experiment testing workflow. In this context, the VITALISE project is working to harmonize Living Lab research and data capture protocols and to provide controlled processing access to captured data to industrial and scientific communities. In this paper, we present the initial design and implementation of our synthetic data generation approach in the context of VITALISE Living Lab controlled data processing workflow, together with identified challenges and future developments. By uploading data captured from Living Labs, generating synthetic data from them, developing analysis locally with synthetic data, and then executing them remotely with real data, the utility of the proposed workflow has been validated. Results have shown that the presented workflow helps accelerate research on artificial intelligence, ensuring compliance with data protection laws. The presented approach has demonstrated how the adoption of state-of-the-art synthetic data generation techniques can be applied for real-world applications.