Endoscopic spine surgery (ESS) has traditionally been employed for lumbar disc herniation (LDH). Recent innovations in surgical methods and technologies have expanded its range to address other spinal pathologies, providing minimally invasive solutions with potential clinical benefits. Our review aims to summarize the applications, clinical outcomes, and limitations of ESS beyond LDH, focusing on its role in complex spinal conditions such as stenosis, thoracic disc herniation, spinal tumors, synovial cysts, and failed back surgery syndrome. A thorough review of the literature was conducted to assess and summarize the current evidence regarding ESS applications for spinal conditions beyond LDH surgery. Areas of focus included innovations in technology and technique, as well as comparisons with conventional open surgical methods. ESS shows notable potential across different spinal conditions by providing minimally invasive alternatives to traditional open surgery. Its use could be associated with reduced surgical morbidity, shorter recovery times, and improved patient outcomes. In particular, ESS is versatile in addressing both degenerative and neoplastic conditions of the spine. Despite this, challenges such as technical complexity, steep learning curves, and limited indications for certain pathologies remain as barriers to wider adoption. ESS is evolving in spine surgery, extending its utility beyond LDH surgery. While the current evidence largely supports its clinical efficacy, further studies are needed to address the present limitations and optimize its application. Future developments in surgical training and technology will likely enhance its adoption and broaden its clinical indications.

Distal junctional kyphosis (DJK) and distal junctional failure (DJF) are known complications of adult multilevel spinal fusion surgery. Previous literature has extensively investigated proximal junctional kyphosis and proximal junctional failure, but DJK and DJF are relatively understudied. This study investigates the association between bone mineral density (BMD) and DJK/DJF via a systematic review and meta-analysis. A literature search was conducted across PubMed, Cochrane, Web of Science, Embase, and Scopus to find studies reporting DJK, DJF, and BMD. A 12-month minimum follow-up and radiographic biomarker for BMD (Hounsfield units [HU] or a T-score) individually reported for each patient type were required for inclusion. Studies that did not report individualized biomarkers but provided averaged estimates of the effect of BMD on DJK/DJF development were used for systematic review. Our search yielded 12 unique studies with 1094 patients, of which 5 studies with a total of 519 patients were suitable for comparison by meta-analysis. Patients who developed DJK/DJF had significantly lower HUs (113.17 ± 33.86) than patients who did not develop DJK/DJF (142.51 ± 41.39). No significant difference was found with regard to dual-energy X-ray absorptiometry measurements, age, or body mass index between patients who did and did not develop DJK/DJF. Patients who developed DJK/DJF had significantly lower computed tomography-measured HU as compared to those without DJK/DJF. Our findings highlight the potential importance of BMD evaluation with computed tomography prior to multilevel spine fusion surgery, though further research would be helpful to evaluate the significance of dual-energy X-ray absorptiometry-based BMD measurements on DJK/DJF development.

Thoracic disc herniations (TDHs) are rare, and surgery is typically reserved for patients with radiculopathy, myelopathy, or intractable back pain. Despite established algorithms, the optimal surgical strategy remains debated. What are the clinical, surgical, and radiological outcomes of anterior and posterior surgical approaches for TDHs over a 10-year period? A retrospective analysis of 54 patients who underwent surgery for TDHs (2013-2022) was performed. Patients were grouped by surgical approach: anterior (34 patients) and posterior (20 patients). Data included preoperative and postoperative outcomes such as operative times, hospital stays, complications, reoperations, and assessments using the Frankel scale, Nurick score, and Visual Analog Scale (VAS) for pain. Both approaches improved clinical outcomes. No significant differences in postoperative Nurick or VAS pain scores were observed. However, the anterior approach showed better Frankel score improvements but was associated with longer operative times and hospital stays. Complications were more frequent in the anterior group. Both approaches effectively alleviate symptoms in symptomatic TDHs. The anterior approach offers greater neurological improvement but carries higher complication risks. Surgical strategy should be tailored based on herniation characteristics and surgeon expertise. Anterior approaches are ideal for central, large, or calcified herniations, while posterior approaches are preferable for lateral ones.

Background/Objectives: Lumbopelvic fixation (LPF) is essential for stabilizing the lumbosacral junction (LSJ) in cases of trauma, tumors, and other pathologies. While minimally invasive percutaneous techniques are preferred when feasible, open LPF remains necessary when direct sacral access is required. This study describes a modified open LPF technique designed to minimize invasiveness while maintaining effective stabilization. Methods: We present a case of sacral metastasis requiring LPF. The surgical technique involves a linear midline incision, meticulous subfascial dissection to preserve the Longissimus thoracis and Iliocostalis lumborum muscles, and a subcutaneous supra-fascial approach for iliac screw placement guided by intraoperative CT navigation. A U-shaped cross-link is used for final construct stability. The case illustrates the application of this technique in a 56-year-old female patient with metastatic breast carcinoma involving the sacrum, complicated by nerve compression and urinary retention. Results: The patient underwent successful LPF with nerve root decompression and partial tumor resection. Postoperatively, she experienced no new neurological deficits and demonstrated progressive improvement in sphincter function. The described surgical approach minimized soft tissue disruption, blood loss, and potential complications associated with more extensive dissection. Six-month follow-up CT scans confirmed the stability of the LPF construct and the residual lesion. Conclusions: When open LPF is unavoidable, the described subcutaneous supra-fascial approach for iliac screw placement, combined with muscle preservation and a U-shaped cross-link, offers a less invasive alternative that minimizes soft tissue trauma, reduces potential complications, and facilitates faster patient recovery. This technique can be particularly beneficial in patients with sacral metastases requiring nerve decompression and tumor resection.

Background: Congenital craniovertebral junction anomalies (CCVJAs) encompass a diverse range of conditions characterized by distorted anatomy and significant variation in the pathways of neurovascular structures. This study aims to assess the safety and feasibility of tailoring posterior fixation for CCVJAs through intraoperative CT-based navigation. Methods: An in-depth retrospective analysis was conducted on eight patients diagnosed with CCVJAs (excluding Arnold–Chiari malformation). These patients underwent posterior fixation/arthrodesis facilitated by intraoperative CT-based navigation. The analysis included an examination of the fixation strategies, complication rates, length of stay, post-operative complications, and success of arthrodesis. Additionally, a comprehensive literature review was undertaken to contextualize and compare our findings. Results: Patients undergoing CVJ posterior fixation with intraoperative CT-based navigation exhibited a flawless record, devoid of complications related to the damage to neurovascular structures, as well as any instances of screw misposition, pullout, or breakage (0 out of 36 total screws). Furthermore, the entire cohort demonstrated a 100% arthrodesis rate. None of the patients required treatment with an occipital plate. Conclusions: The incorporation of intraoperative CT-based navigation proves to be an invaluable asset in executing CVJ posterior fixation within the context of CCVJAs. This technology facilitates the customization of posterior constructs, a crucial adaptation required to navigate the anatomical challenges posed by these anomalies. The secure placement of screws into the occipital condyles, made possible by navigation, has proven highly effective in achieving CVJ fixation, obviating the need for an occipital plate. This technological leap represents a significant advancement, enhancing the safety, precision, and overall outcomes for patients undergoing this surgical procedure, while concurrently reducing the necessity for more invasive and morbid interventions.