Nasotracheal intubation is a standard blind procedure associated with various complications. The selection of the appropriate nostril is crucial to preventing most of these complications. The present study aimed to evaluate the predictive ability of cone-beam CT (CBCT) images to select the correct nostril for nasotracheal intubation. The study encompassed 60 patients who underwent maxillofacial surgery with nasotracheal intubation under general anaesthesia. While the anaesthetist made the appropriate nostril selection clinically according to a simple occlusion test and spatula test, the radiologist made the selection after analysing various CBCT findings such as the angle and direction of nasal septum deviation (NSD), minimum bone distance along the intubation path, and the presence of inferior turbinate hypertrophy. The appropriateness of these choices made blindly at different times was evaluated using descriptive statistics, chi-squared test, and independent samples t-test. The study found that 83.3% of the suggested nostril intubations were successful. We also observed that intubation duration was longer when inferior turbinate hypertrophy was present (P = .031). However, there was no statistical relationship between the presence of epistaxis and septal deviation (P = .395). Nonetheless, in 64.3% of cases with epistaxis, the intubated nostril and the septum deviation direction were the same. Pre-operative evaluations using CBCT can aid anaesthetists for septum deviation and turbinate hypertrophy, as both can impact intubation success rates and duration.

Aim: We aimed to evaluate anesthesia-related complications in pediatric patients undergoing dental treatment under general anesthesia (GA). Materials and Methods: After ethical committee approvel, the records of pediatric patients who were operated between 01.09.2020-01.09.2022 at Selcuk University Faculty of Dentistry General Anesthesia and Sedation Clinic were evaluated with regards of demographic data, ASA, comorbidities, duration of anesthesia, recovery time, cardiac/pulmonary complications, and unanticipated hospitalization rate. The patients were divided into 3 groups according to age as group 1 (0-3 years), group 2 (3-6 years), group 3 (>6 years). Results: The total number of patients were 398. All patients were between 2-15 years of age. Since the number of patients in group 1 is 7, it was not statistically evaluated in comparisons. The mean duration of anesthesia for all patients was 96.9 minutes, the times in group 2 and group 3 were 100.3 minutes and 88.7 minutes, respectively, and the difference between groups 2 and 3 was statistically significant (p=0.003).The mean BMI values of all patients, in group 2 and in group 3 were 16.1, and 18.6, respectively and the difference between group 2 and 3 was statistically significant (p<0.001). In group 2, the number of ASA 1 and 2 patients were 87.2% and 12.1%, respectively. In group 3, the number of ASA 1 and 2 patients were 56.4% and 40.6%, respectively. The difference between group 2 and 3 regarding ASA score was statistically significant (p<0.001). Conclusion: We have not found any patients under 3 years of age who were at risk according to the FDA warning regarding the risks of anesthetic drugs. No cardiac or pulmonary complications were observed in any of our patients and there were no unexpected hospitalizations. Key Words: dental treatment, general anesthesia, pediatric dentistry

Objectives: We aimed to study the impact of cold throat packs (TP) on postoperative sore throat (POST) and nausea-vomiting (PONV) and to investigate whether cold irrigation fluids increase TP’s cooling effect. Background: Although TPs are used in surgical operations to protect the airway by creating a mechanical barrier, they may be associated with adverse events. Methods: TPs were kept at +4 °C before being placed in all patients’ nasopharynx, and the nasopharyngeal area was rinsed and aspirated with a cold irrigation fluid every 20 min. Core body temperature, the amount of physiological saline, demographic, operational, and anesthesia-related data, and signs and symptoms of PONV and POST were recorded. In addition, patients were divided into two subgroups, ‘hot’ and ‘cold’ according to nasotracheal temperature. Results: The nasotracheal area was successfully maintained at lower temperatures throughout the surgical procedure (p < 0.001). The occurrence of POST at the 10^th minute was significantly low in Group Cold (p = 0.002). Nausea was detected in 26 of 84 patients (30.9%) without a significant difference between groups, antiemetics was used in 14 of 26 patients (53.8%), and none experienced vomiting. Conclusions: Cold applications can reduce POST and improve postoperative patient comfort at a low cost.

Background/Aims: Cardiac arrest (CA) is a leading cause of mortality worldwide, with survival outcomes heavily dependent on prompt recognition and intervention. Basic Life Support (BLS) training is critical for equipping healthcare professionals with the skills necessary to manage such emergencies effectively. Tailored BLS training is essential in dentistry, where emergencies like CA, though rare, can have severe consequences. This study evaluated the effectiveness of a structured BLS training program for dental residents at Selçuk University Faculty of Dentistry, incorporating theoretical, practical, and video-based instruction components. Material and Methods: A total of 151 volunteer dental residents participated in a structured BLS training program conducted between May 14-17, 2024. Training included theoretical lectures, hands-on practice on mannequins, and a preparatory video covering BLS interventions for adults, children, and infants. Knowledge acquisition was measured using pre-tests, post-tests, and a retention test one month after training. Participants’ demographic data and prior BLS experience were also evaluated. Results: Participants demonstrated significant improvement in knowledge immediately after training, with retention remaining above pre-test levels one month later. In analyzing the number of participants who answered the questions correctly in the post-training tests, p

Sugammadex reverses the effects of steroidal neuromuscular-blocking agents, such as rocuronium, by encapsulating these agents. Its cardiovascular adverse effects include QTc prolongation, hypotension, bradycardia, atrioventricular block, atrial fibrillation, and asystole. Additionally, rocuronium has cardiac side effects, such as bradycardia, hypotension, cardiac arrest, circulatory collapse, and ventricular fibrillation. Herein, we investigated the effects of sugammadex, rocuronium, and combined rocuronium + sugammadex on cardiac electrophysiological parameters. In vitro experiments were performed using ventricular myocytes obtained from male Wistar rats. Myocyte contraction and relaxation responses were recorded along with action potential (AP), and L-type calcium (ICaL) and potassium channel currents (Ito, Iss, and IK1). Sugammadex caused dose-dependent decreases in myocyte contraction and relaxation responses. Rocuronium had no effect in this respect, whereas its co-administration with sugammadex led to decreased contraction responses. Sugammadex prolonged the AP repolarization phase, whereas rocuronium prolonged all AP phases. Co-administration of sugammadex and rocuronium did not significantly affect AP parameters. Sugammadex suppressed the peak ICaL value, while rocuronium caused an even greater decrease. Co-administration of these drugs further decreased the current-voltage characteristics of the ICaL. However, no significant effects were observed on the potassium currents. Separate or combined administration of sugammadex and rocuronium had various effects on myocyte contractility, AP, and ICaL, which could cause significant changes leading to adverse cardiac events. Further experimental and clinical studies are required to understand the clinical consequences of the modulatory effects of these drugs on cardiac electrophysiological parameters.

Objectives: Dexmedetomidine is a potent and highly selective alpha-2 adrenergic receptor agonist recognized for its sedative, hypnotic, analgesic, and sympatholytic properties. The diverse cardiac and hemodynamic effects of dexmedetomidine have been thoroughly documented. Consequently, we investigated its impact on electrophysiological parameters, including action potential and contraction in ventricular myocytes. Methods: Freshly isolated ventricular myocytes from adult Wistar rats were used for experiments. The contraction and relaxation responses, action potentials, L-type calcium currents, and potassium channel currents of the myocytes were recorded using a video-based contractility system and the whole-cell patch clamp technique. Results: While higher concentrations of dexmedetomidine progressively inhibit the contractile responses of cardiomyocytes, they did not significantly impact the action potential repolarization phase or potassium currents (including both transient outward and inward rectifiers). However, there was a decrease in L-type calcium currents, particularly at potential values ranging from 0 to 30 mV. Furthermore, although dexmedetomidine shifted the V50 value toward more positive values in the deactivation-reactivation curve of the L-type calcium channel, no statistically significant difference was observed. Conclusions: Our study demonstrates that dexmedetomidine causes a dose-dependent reduction in contractility and decreases calcium currents. These findings indicate that dexmedetomidine may significantly influence the mechanical and electrical functions of cardiac cells. Additional research is needed to clarify the molecular mechanisms underlying these changes.