This study investigated the associations of green tea, coffee, and caffeine consumption with self-report lifetime depression in the Korean population using data from the Korean National Health and Nutrition Examination Survey. In total, 9576 participants (3852 men and 5724 women) aged 19 years or older were selected for the present study. Green tea, coffee, and caffeine consumption levels were assessed with a validated food frequency questionnaire. Multivariate logistic regression analysis was used to determine the odds ratios (OR) and 95% confidence intervals (CIs) for depression according to green tea, coffee, and caffeine consumption. Frequent green tea consumers (≥3 cups/week) had 21% lower prevalence of depression (OR = 0.79, 95% CI = 0.63–0.99, p for trend = 0.0101) than green tea non-consumers after adjustment for potential confounders. Likewise, frequent coffee drinkers (≥2 cups/day) had 32% lower prevalence of depression (OR = 0.68, 95% CI = 0.55–0.85, p for trend = 0.0026) than coffee non-drinkers after adjustment for potential confounders. Also, participants in the highest quartile of caffeine consumption had 24% lower prevalence of depression than those in the lowest quartile (OR = 0.76, 95% CI = 0.62–0.92, p for trend = 0.0032). Frequent consumption of green tea, coffee, or caffeine was associated with a reduced prevalence of self-report lifetime depression in Korean adults. A prospective study and randomized clinical trials should be conducted to confirm the inverse relationships of green tea and coffee consumption with risk of depression.

We examined gender differences in the association between dietary patterns and the risk of hypertension, using the Korean Genome and Epidemiology Study data. A total of 5090 participants (2457 men and 2633 women) aged 40–69 years without hypertension at baseline were selected. Dietary patterns were obtained using factor analysis based on 26 food groups, evaluated by a validated semi-quantitative food frequency questionnaire at baseline. Hypertension was defined as systolic blood pressure ≥ 140 mmHg or diastolic blood pressure ≥ 90 mmHg, or the use of antihypertensive medication using the biennial measurements. Multivariate Cox proportional hazards models were used to examine the associations between dietary patterns and hypertension. Four dietary patterns were extracted: coffee, fat, and sweets; prudent; whole grains and legumes; and traditional (men)/Western (women). Women in the highest tertile of the whole grains and legumes pattern scores showed a lower risk of incident hypertension compared with those in the lowest tertile (hazard ratio = 0.77, 95% confidence interval = 0.59–1.00, p-trend = 0.048). Other dietary patterns were not associated with hypertension in either men or women. A diet rich in whole grains and legumes is inversely associated with the risk of hypertension in Korean women, suggesting a gender difference in the association between diet and hypertension.