To present the 2-year clinical outcomes of short-span implant-supported hybrid composite restorations, namely single crowns (SCs) and fixed partial prostheses (FPPs), produced using tilting stereolithography (TSLA). This retrospective study was based on data from a cohort 145 patients, treated between June 2021 and June 2023, with 185 fixed short-span implant-supported hybrid composite restorations (Irix Max®, RD Printing, Thiene, Vicenza, Italy) produced using tilting stereolithography (TSLA). The restorations were manufactured through a fully digital, model-free workflow, which included intra-oral scanning, computer-aided design (CAD) and additive manufacturing with the TSLA system (Dfab®, RD Printing). Primary outcome measures included marginal fit, occlusal and interproximal contact quality and colour matching of the restorations, all evaluated by two experienced clinicians (a prosthodontist and a periodontist, who were not directly involved in the treatment of the patients). Each restoration was rated at the time of delivery, using a 5-point scale (5 being excellent, 4 satisfactory, 3 acceptable, and 2 or 1 indicating poor quality). The secondary outcomes assessed comprised the survival and success (i.e. absence of complications) rates of the restorations, during the entire follow-up period. Statistical analysis was performed on the collected data. Among the 3D-printed hybrid composite restorations, 95 had a 2-year follow-up, whereas 90 had only a 1-year follow-up. Overall, the restorations demonstrated excellent performance in terms of marginal fit and contact accuracy, both occlusal and interproximal. Their aesthetic integration was also deemed satisfactory. During the follow-up period, all restorations remained functional, with a low complication rate (1.0 % biological and 3.7 % prosthetic complications), resulting in an overall success rate of 95.1 %. Implant-supported short-span hybrid composite restorations manufactured using TSLA technology demonstrated high clinical accuracy and showed a low rate of complications over a 2-year period. TSLA printing technology shows potential for the definitive prosthetic treatment of small edentulous spaces.

To evaluate the 3-year clinical performance of additively manufactured (AM) hybrid composite short-span implant-supported restorations fabricated through tilting stereolithography (TSLA) within a fully digital workflow. This retrospective clinical study included 218 patients rehabilitated with 278 implant-supported restorations fabricated from a ceramic-filled hybrid composite material using TSLA technology. The restorations comprised 207 single crowns (SCs) and 71 fixed partial dentures (FPDs), supported by 360 implants. All rehabilitations were produced through a complete digital workflow. Primary outcomes included marginal adaptation, occlusal and interproximal contact quality, and chromatic integration, assessed at delivery by two independent evaluators using a 5-point scoring system. Secondary outcomes included restoration survival and restoration success during follow-up. Kaplan-Meier survival analysis was performed. At delivery, both evaluators assigned predominantly excellent or satisfactory scores for marginal adaptation, occlusal contacts, interproximal contacts and chromatic integration, with no significant differences between restoration types (p > 0.05). During follow-up, 3 biological complications (1.1%) and 19 prosthetic complications (6.8%) were recorded, including 7 cases of abutment screw loosening, 6 decementations and 6 restoration fractures. Two implants failed during early healing, while three patients were lost to follow-up during the third year. Kaplan-Meier analysis revealed a cumulative restoration survival rate of 97.8% and an overall restoration success rate of 92.0% after 3 years. Within the limitations of this short-term study, TSLA-manufactured hybrid composite restorations demonstrated favourable clinical accuracy, high survival rates and acceptable short-term clinical performance. Hybrid composite restorations fabricated through TSLA may represent a promising option for definitive short-span implant-supported rehabilitations within contemporary digital prosthodontic workflows.

The dental system is a complex mechanism that includes a number of connective tissue structures that have specific properties and perform a number of functions, in particular, protective. One of the main barrier elements of the oral cavity is the mucous membrane lining it, throughout its length, having a different morphological structure. The most frequently pathological process is the periodontal tissue, which consists of attached and non-attached gums, bone alveoli, cementum of the tooth root and periodontal ligament of the tooth. At present, all periodontal diseases are usually divided into inflammatory and primary dystrophic, while a number of authors have found that in its pure form, the dystrophic process is detected no more than 1–8% of all diseases and is characterized as a generalised process against the background of general somatic pathology. The frequency of occurrence of periodontal diseases varies from 60 to 85% in the working population, which determines the relevance of studying therapeutic measures aimed at their relief and is the purpose of this study.The aim of the study was to investigate the angioprotective and anti-inflammatory properties of Vaccinium mytillus, Vaccinium arctostaphylos in experiment.Materials and methods. In this experimental work, the authors developed a model of periodontal damage in experimental animals (Vistar rats, weight – 25–300 g) under the conditions of drug loading with chloral hydrate, in accordance with the Directive on the Protection of Vertebrate Animals of 2000 and extracts from the act of Local Ethical Committee. The model was created by inflicting a single injury with a sharp object in the projection of the interdental space in the frontal segment of the mandible. The proper pathological condition was recorded on the 5–7th day; the verification of the morphological changes in some of the animals was being made by fragmenting the frontal segment of the lower jaw, followed by a pathological and histological examination. Then, the control group of animals was treated applied gel, made of Vaccinium mytillus, Vaccinium arctostaphylos to stop the process for 2 weeks. For comparison, the main group was treated with a gel without the inclusion of a drug component. At the end of the course of conservative therapy, according to the design of the study, biopsy specimens were taken again in both groups to evaluate the results of the conservative therapy provided.Results. According to the patho-histological study in the biopsy specimens of the damaged periodontium, the animals, revealed morphological disorders corresponding to chronic periodontal disease. At the stage of treatment in the control group, positive dynamics was noted both according to the clinical examination and after the pathological and histological examination of biopsy specimens in the comparison groups.Conclusions. The obtained results indicate the presence of anti-inflammatory and angioprotective effect of medicament compositions based on Vaccinium mytillus, Vaccinium arctostaphylos, which will be further tested in clinical trials.