Neha Nischal

Dr. Neha Nischal

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Research Focus & Metrics

Academic Career Length

10Years (2017-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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28 January 2023 in Life
Verified
Journal Article
Open access
PDF file
NNNeha Nischal
Neha Nischal
KIKarthikeyan P Iyengar
Karthikeyan P Iyengar
DHDeepak Herlekar
Deepak Herlekar
RBRajesh Botchu
Rajesh Botchu
A healthy articular cartilage is paramount to joint function. Cartilage defects, whether acute or chronic, are a significant source of morbidity. This review summarizes various imaging modalities used for cartilage assessment. While radiographs are insensitive, they are still widely used to indirectly assess cartilage. Ultrasound has shown promise in the detection of cartilage defects, but its efficacy is limited in many joints due to inadequate visualization. CT arthrography has the potential to assess internal derangements of joints along with cartilage, especially in patients with contraindications to MRI. MRI remains the favored imaging modality to assess cartilage. The conventional imaging techniques are able to assess cartilage abnormalities when cartilage is already damaged. The newer imaging techniques are thus targeted at detecting biochemical and structural changes in cartilage before an actual visible irreversible loss. These include, but are not limited to, T2 and T2* mapping, dGEMRI, T1ρ imaging, gagCEST imaging, sodium MRI and integrated PET with MRI. A brief discussion of the advances in the surgical management of cartilage defects and post-operative imaging assessment is also included.

1 December 2021 in Asian Spine Journal
Verified
Journal Article
Open access
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NNNeha Nischal
Neha Nischal
STShalini Tripathi
Shalini Tripathi
JSJatinder Pal Singh
Jatinder Pal Singh
Study Design: We performed a prospective observational study of 52 patients who were clinically suspected of cervical spondylotic myelopathy (CSM), based on the modified Japanese Orthopaedic Association (mJOA) score, and were referred for magnetic resonance imaging (MRI) of the cervical spine. Purpose: To evaluate the quantitative parameters of the diffusion tensor imaging (DTI) matrix (fractional anisotropy [FA] and apparent diffusion coefficient [ADC] values) and determine the subsequent correlation with the clinical assessment of disease severity in CSM. Overview of Literature: Conventional MRI is the modality of choice for the identification of cervical spondylotic changes and is known to have a low sensitivity for myelopathy changes. DTI is sensitive to disease processes that alter the water movement in the cervical spinal cord at a microscopic level beyond the conventional MRI. Methods: DTI images were processed to produce FA and ADC values of the acquired axial slices with the regions of interest placed within the stenotic and non-stenotic segments. The final quantitative radiological derivations were matched with the clinical scoring system. Results: Total 52 people (24 men and 28 women), mean age 53.16 years with different symptoms of myelopathy, graded as mild (n=11), moderate (n=25), and severe (n=16) as per the mJOA scoring system, underwent MRI of the cervical spine with DTI. In the most stenotic segments, the mean FA value was significantly lower (0.5009 +/- 0.087 vs. 0.655.7 +/- 0.104, p<0.001), and the mean ADC value was significantly higher (1.196.5 +/- 0.311 vs. 0.9370 +/- 0.284, p<0.001) than that in the non-stenotic segments. The overall sensitivity in identifying DTI metrics abnormalities was more with FA (87.5%) and ADC (75.0%) than with T2 weighted images (25%). Conclusions: In addition to the routine MRI sequences, DTI metrics (FA value better than ADC) can detect myelopathy even in patients with a mild grade mJOA score before irreversible changes become apparent on routine T2 weighted imaging and thus enhance the clinical success of decompression surgery.

20 March 2023 in Indian Journal of Radiology and Imaging
Verified
Journal Article
Open access
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ESEmily Smith
Emily Smith
NNNeha Nischal
Neha Nischal
JMJennifer Murphy
Jennifer Murphy
CAChristine Azzopardi
Christine Azzopardi
KIKarthikeyan P Iyengar
Karthikeyan P Iyengar
RBRajesh Botchu
Rajesh Botchu
Introduction A unilateral or bilateral pars interarticularis defect (spondylolysis) is a leading cause of axial back pain in adolescent athletes. Currently, a spectrum of imaging modalities is used for assessment of pars interarticularis defects. Objectives The aim of this study is to compare the accuracy of chemical shift sequence (magnetic resonance imaging [MRI]) technique to conventional MRI sequences in the detection of pars defects. Patients and Methods Conventional T1, T2, and short tau inversion recovery sagittal and axial, as well as “in-” and “out-” phase chemical shift sagittal MRI sequences of 70 consecutive patients referred for low back pain were reviewed. Demographic details, clinical indication, and presence/diagnosis of pars defects using a 5-point Likert scale on both conventional and chemical shift MRI sequences. Spearman's correlation was used for statistical analysis. Intraclass correlation coefficient analysis was evaluated to assess the intraclass reliability between observers. Data were analyzed using DATAtab web-based statistics software (2022). Results A total of 70 patients with an average age of 54.34 years with a female predominance were included. There were 11 pars defects in the cohort. Both in and out phases of chemical shift imaging were able to identify pars defect and intact pars. However, out phase was relatively better in delineating pars defects, while the in phase was superior in identifying an intact pars, though this was not statistically significant. There was good intra- and interobserver reliabilities. Conclusion Chemical shift MRI sequence is a quicker, complementary technique to assess and analyze pars interarticularis confidently than conventionally utilized MRI sequences in patients being evaluated for axial back pain.

13 August 2024 in Clinical Radiology
Verified
Journal Article
Closed access
SSSonal Saran
Sonal Saran
KSKAPIL SHIRODKAR
KAPIL SHIRODKAR
MHMohsin Hussein
Mohsin Hussein
ASA.B. Shah
A.B. Shah
SCShashank Chapala
Shashank Chapala
RBRajesh Botchu
Rajesh Botchu

7 April 2025 in Skeletal Radiology
Verified
Journal Article
Closed access
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DSDharmendra Kumar Singh
Dharmendra Kumar Singh
DJDivesh Jalan
Divesh Jalan
ANAarushi Narwani
Aarushi Narwani
NKNishith Kumar
Nishith Kumar
ARAshish Rustagi
Ashish Rustagi
NNNeha Nischal
Neha Nischal

6 May 2023 in Indian Journal of Radiology and Imaging
Verified
Journal Article
Open access
PDF file
RBRajesh Botchu
Rajesh Botchu
NNNeha Nischal
Neha Nischal
BBBhuvan Botchu
Bhuvan Botchu
KIKarthikeyan P Iyengar
Karthikeyan P Iyengar
Rib biopsy can be challenging. A spectrum of bone biopsy techniques are available to undertake Rib Bone biopsy and yield a histological specimen. In this technical report, we described a new Piggyback technique of performing rib biopsy to decrease the incidence of pneumothorax and consolidate diagnostic accuracy.