Laura Valentini

Dr. Laura Valentini

Department of Biomolecular Sciences, Urbino, Marche, Italy
orcid

Research Focus & Metrics

Academic Career Length

33Years (1994-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 February 2017 in Building and Environment
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Journal Article
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GGGiovanni Battista Goffredo
Giovanni Battista Goffredo
Stefano AccoroniStefano Accoroni
Stefano Accoroni
CTCecilia Totti
Cecilia Totti
TRTiziana Romagnoli
Tiziana Romagnoli
Laura ValentiniLaura Valentini
Laura Valentini
PMPlacido Munafò
Placido Munafò

19 October 2021 in Sustainability
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Journal Article
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Paola CoratzaPaola Coratza
Paola Coratza
IBIrene Bollati
Irene Bollati
VPValeria Panizza
Valeria Panizza
BPBrandolini Pierluigi
Brandolini Pierluigi
DCDoriano Castaldini
Doriano Castaldini
MPManuela Pelfini
Manuela Pelfini
In the framework of geosite management, specific targeted symbols for geomorphological legends are still lacking. Concerning geosites of geomorphological interest, geomorphological mapping requires targeted symbols in relation to goals and applications, either concerning geomorphic hazards and risk detection or the enhancement of resources, in particular those related to cultural heritage and, hence, geoheritage. A new methodology for mapping geo(morpho)heritage on geomorphological maps is presented in this paper. Nine iconic examples from the Italian landscape, selected in different morphogenetic and morphoclimatic contexts, are proposed to test the methodology in relation to point, polyline and polygon features. Moreover, guidelines for mapping are suggested according to the importance of the site and to the complexity of processes characterizing each case study.

25 June 2019 in PLOS ONE
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RBRoberta De Bellis
Roberta De Bellis
MPMaria Piera Piacentini
Maria Piera Piacentini
MMMaria Assunta Meli
Maria Assunta Meli
Michele MattioliMichele Mattioli
Michele Mattioli
MMMichele Menotta
Michele Menotta
LCLaura Chiarantini
Laura Chiarantini
Ceterach officinarum Willd is a plant widespread throughout Europe and used in southern Italy as a diuretic. Beliefs in the benefits of C. officinarum aqueous extract in the treatment of calcium oxalate kidney stones are widely held. Little is known, however, about the actual mechanism of its antilithiatic action. Our results in this in vitro study corroborate C. officinarum aqueous extract as a good source of antioxidants with a high antioxidant effects. Our results also demonstrate a major impact of C. officinarum aqueous extract on in vitro induced calcium oxalate crystallization kinetics and crystal morphology, showing its critical role in kidney stone formation and/or elimination. We show that progressively increasing doses of C. officinarum aqueous extract cause a sequence of effects. A powerful inhibitory action on calcium oxalate monohydrate (COM) growth and aggregation is first observed. C. officinarum aqueous extract also appears highly effective in stimulating nucleation increasing the number and reducing the size of COM crystals, which become progressively thinner, rounded and concave in a dose-dependent manner. These shape-modified COM crystals are known to be less adherent to renal tubular cells and more easily excreted through the urinary tract preventing kidney stone formation. Further, C. officinarum aqueous extract promotes the formation of calcium oxalate dihydrate (COD) rather than the monohydrate so that, at the highest concentrations used, only COD crystals are observed, in significant greater numbers with a clear reduction in their size, in a dose-dependent manner. Furthermore, AFM analyses allowed us to reveal the presence of C. officinarum component(s) on the surfaces of COD and modified COM crystals. The crystal surface adsorbed component(s) are shown to be similarly active as the total aqueous extract, suggesting a trigger factor which may direct crystal modification towards COD forms. In urolithiasis pathogenesis COD crystals are less dangerous than the COM forms due to their lower affinity for renal tubular cells. Our results are important in understanding the mechanisms which guide the modification induced by C. officinarum on the crystallization process. Based on these data, together with no adverse toxic effect being observed on the in vitro model of human intestinal enterocytes, C. officinarum aqueous extract could represent an attractive natural therapy for the treatment of urolithiasis.

2 December 2020 in Geoscience Communication
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ONOlivia Nesci
Olivia Nesci
Laura ValentiniLaura Valentini
Laura Valentini
We present a method to educate the public about landscapes that uses artistic works to broaden the audience, entice people to learn about landscapes in a personal and human context, and thus encourage them to preserve the natural heritage. To this end, we use narratives about a place, in plain language, accompanied by visual presentations, original poetry, and ancient music. Several studies encourage the use of art since it can help to synthesize and convey complex scientific information and create a celebratory and positive atmosphere. Evidence suggests that the arts can deeply engage people by focusing on emotions rather than relying only on comprehension, which is often emphasized in science communication. The multidisciplinary approach arouses an emotional and intellectual experience that enables a personal connection to the place. The work is part of a larger multidisciplinary project covering 20 sites in the Marche region (central Italy), which includes scientific information on geological–geomorphological genesis, trekking itineraries, poetry, ancient music, video, and cultural offerings. The project resulted in live multidisciplinary performances, a book, a DVD, and a website. To give a taste of how we work among the many amazing landscapes of the Marche region, we focus here on three sites from the north, the centre, and the south of the region, namely the sea cliff of San Bartolo, the flatiron of Mount Petrano, and the fault of Mount Vettore, chosen as examples for their different processes of genesis and evolution. In the long run, our goal is to promote a deeper understanding of landscapes by integrating their origin and physical aesthetic with their cultural and artistic heritage. In doing so, we intend to inspire people to have a new perception of geosites, starting from their physical beauty, building on scientific study and cultural history, and arriving at the knowledge of their social importance. So far, our direct experience with the public has been highly encouraging. The participation at our live shows demonstrated a great interest in geological history, a result that is relevant for the development of geotourism. The method demonstrates the potential to develop a strong personal involvement of visitors with the places, stimulating their curiosity to know how and why that place was formed, and, finally, the desire to visit and protect it.

17 February 2017 in Journal of Toxicology and Environmental Health, Part B
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Journal Article
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Matteo GiordaniMatteo Giordani
Matteo Giordani
MMMichele Mattioli
Michele Mattioli
PBPaolo Ballirano
Paolo Ballirano
APAlessandro Pacella
Alessandro Pacella
MCMarco Cenni
Marco Cenni
Laura ValentiniLaura Valentini
Laura Valentini
Erionite is a zeolite representing a well-known health hazard. In fact, exposure of humans to its fibers has been unequivocally associated with occurrence of malignant mesothelioma. For this reason, a multi-methodological approach, based upon field investigation, morphological characterization, scanning electron microscopy (SEM)/energy-dispersive spectroscopy (EDS) chemical analysis, and structure refinement through X-ray powder diffraction (XRPD), was applied to different samples of potentially carcinogenic erionite from Northern Italy. The studied crystals have a chemical composition ranging from erionite-Ca to erionite-Na and display variable morphologies, varying from prismatic, through acicular and fibrous, to extremely fibrous asbestiform habits. The fibrous samples were characterized by an unusual preferred partition of aluminum (Al) at tetrahedral site T1 instead of tetrahedral site T2. Further, a mismatch between the a-parameter of erionite-Ca and levyne-Ca that are intergrown in the asbestiform sample was detected. This misfit was coupled to a relevant micro-strain to maintain structure coherency at the boundary. Erionite occurs in 65% of the investigated sites, with an estimated quantity of 10 to 40 vol% of the associated minerals. The presence of this mineral is of concern for risk to human health, especially if one considers the vast number of quarries and mining-related activities that are operating in the zeolite host rocks. The discovery of fibrous and asbestiform erionite in Northern Italy suggests the need for a detailed risk assessment in all Italian areas showing the same potential hazard, with specific studies such as a quantification of the potentially respirable airborne fibers and targeted epidemiological surveillance.

30 June 2022 in Geosciences
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Journal Article
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Laura ValentiniLaura Valentini
Laura Valentini
VGVeronica Guerra
Veronica Guerra
Maurizio LazzariMaurizio Lazzari
Maurizio Lazzari
Geoheritage is a geotourism resource that could lead to the sustainable development of society, and could contribute to information on geological and geomorphological characteristics, education, public awareness on geoconservation, and landscape protection. Understanding this cultural wealth is still limited, since the information available is often specialized. Communication addressed to the emotional sphere can profoundly engage people, and technical information can be transmitted more effectively. For several years, our research group dealt with geoheritage and geotourism in central Italy. This work aimed to investigate different communication methods, such as publications, announcements through social media, conferences, live performances, and field excursions aimed at the emotional involvement of the public. Furthermore, the emotional response of the public was explored through a digital survey. These communication methodologies enabled a broad public reach, without any distinction based on social origin, cultural background, or age. Narrating the landscape through different forms of art creates a personal relationship with the audience. The emotional participation of the people demonstrates the effectiveness of the method in transmitting scientific and cultural themes, such as the origin of the geological landforms, the culture and the traditions that the site generated, and the problems pertaining to its protection and conservation.