Background: Cancer patients may suffer from psychological disorders related to their health condition. Various medical, surgical, and interventional procedures, alongside the distinct tumor localization, have been linked to an elevated predisposition towards psychological disorders, including but not limited to depression, anxiety, post-traumatic stress disorder (PTSD), and cognitive impairments. Objective: To systematically review the literature on neurocognitive rehabilitation of patients before and after brain cancer. Methods: The systematic review was performed according to the PRISMA 2020 guidelines for the systematic review of the PRISMA Group. The literature search was conducted from February 2022 to December 2022 in the databases of PubMed, APA PsycNet, and Web of Science. The focus was on cognitive-behavioural treatments, with Goal Management Training (GMT), and also an app on the iPad- ReMind- that includes psychoeducation, strategy training, and retraining, and new technologies such as virtual reality, in patients with cognitive deficits after neurosurgery. Conclusions: Overall, neurocognitive rehabilitation had an improvement on cancer patients and a recovery of executive and cognitive functions, a better quality of life, and psychological well-being.

Schizophrenia Spectrum Disorders are complex mental health conditions that significantly impact cognitive function and quality of life. While pharmacological and psychotherapeutic interventions are available, their effectiveness remains limited, particularly for negative symptoms and cognitive impairments. These limitations, alongside drug side effects and adherence difficulties, highlight the need for new treatments. Cognitive remediation strategies like Neurofeedback show promise by harnessing neuroplasticity. This systematic review aims to evaluate the neurocognitive and humoral changes induced by Neurofeedback and its therapeutic effects in patients with schizophrenia spectrum disorders. Our review was conducted following PRISMA guidelines. Databases including EMBASE, ScienceDirect, Scopus, PsycINFO, and MEDLINE were searched for relevant studies: 14 studies, 10 RCTs, and 4 Clinical trials were selected. Inclusion criteria encompassed studies involving patients with schizophrenia spectrum disorders, Neurofeedback interventions, and outcomes related to neurocognitive and humoral changes. The Cochrane Risk-of-Bias Tool for randomized trials (RoB 2) was used to assess the quality of included studies. The reviewed studies suggest that Neurofeedback shows promise in addressing various aspects of schizophrenia spectrum disorders. Improvements were observed in processing speed, social functioning, working memory, and emotional regulation. Several studies reported successful modulation of brain activity in regions associated with auditory hallucinations. Neurofeedback training also led to increased functional connectivity between language networks and the default mode network. Some studies found improvements in brain-derived neurotrophic factor (BDNF) levels, self-efficacy, and clinical symptoms in schizophrenia patients. Future research should focus on personalizing Neurofeedback approaches and exploring their mechanisms of action in the context of schizophrenia pathophysiology.

Background Homelessness represents a multifaceted global challenge, closely linked to high rates of substance use disorders (SUDs). This intersection exacerbates health disparities and perpetuates social exclusion; however, effective, context-sensitive interventions remain limited. Objective This scoping review aims to synthesize present evidence on therapeutic, psychological, and social interventions for homeless individuals with SUDs, highlighting effective strategies and identifying gaps to inform future research and clinical practice. Methods Following the PRISMA Extension for Scoping Reviews guidelines, we systematically searched PubMed, Scopus, and ScienceDirect between January and June 2025. Inclusion criteria were peer-reviewed studies from the past decade, published in English, and investigating psychosocial or rehabilitative interventions targeting homeless individuals aged ≥14 with SUDs. Studies exclusively medical or without intervention components were excluded. A total of 23 studies were included. Results Integrated, multidisciplinary interventions—including Housing First combined with assertive community treatment, group-based motivational programs (e.g., AWARE, Tobacco-focused group motivational intervention), harm reduction approaches (e.g., Harm reduction treatment for alcohol, Extended-release naltrexone), and intensive case management—were most effective in reducing substance use, improving mental health and quality of life, and enhancing housing stability. However, the literature showed methodological variability, generally short follow-up periods, and limited incorporation of participants’ perspectives. Conclusion This review underscores the importance of flexible, tailored, and relationship-centered interventions to address the complex needs of homeless populations with SUDs. There is an urgent need for more rigorous and long-term studies, including qualitative insights, to better capture acceptability and feasibility. Strengthening synergies between housing, health, and psychosocial services—particularly in under-researched contexts, such as Italy— could foster more sustainable pathways toward recovery, dignity, and social reintegration.