Electrospun fibres have gained broad interest in biomedical applications, including tissue engineering scaffolds, due to their potential in mimicking extracellular matrix and producing structures favourable for cell and tissue growth. The development of scaffolds often involves multivariate production parameters and multiple output characteristics to define product quality. In this study on electrospinning of polycaprolactone (PCL), response surface methodology (RSM) was applied to investigate the determining parameters and find optimal settings to achieve the desired properties of fibrous scaffold for acetabular labrum implant. The results showed that solution concentration influenced fibre diameter, while elastic modulus was determined by solution concentration, flow rate, temperature, collector rotation speed, and interaction between concentration and temperature. Relationships between these variables and outputs were modelled, followed by an optimization procedure. Using the optimized setting (solution concentration of 10% w/v, flow rate of 4.5 mL/h, temperature of 45 °C, and collector rotation speed of 1500 RPM), a target elastic modulus of 25 MPa could be achieved at a minimum possible fibre diameter (1.39 ± 0.20 µm). This work demonstrated that multivariate factors of production parameters and multiple responses can be investigated, modelled, and optimized using RSM.

In this study, a fibrous composite was developed as synthetic graft for labral reconstruction treatment, comprised of ultra-high molecular weight polyethylene (UHMWPE) fabric, ultrafine fibre of polycaprolactone (PCL), and 45S5 Bioglass^®. This experiment aimed to examine the mechanical performance and cytocompatibility of the composite. Electrospinning and a slurry dipping technique were applied for composite fabrication. To assess the mechanical performance of UHMWPE, tensile cyclic loading test was carried out. Meanwhile, cytocompatibility of the composite on fibroblastic cells was examined through a viability assay, as well as SEM images to observe cell attachment and proliferation. The mechanical test showed that the UHMWPE fabric had a mean displacement of 1.038 mm after 600 cycles, approximately 4.5 times greater resistance compared to that of natural labrum, based on data obtained from literature. A viability assay demonstrated the predominant occupation of live cells on the material surface, suggesting that the composite was able to provide a viable environment for cell growth. Meanwhile, SEM images exhibited cell adhesion and the formation of cell colonies on the material surface. These results indicated that the UHMWPE/PCL/Bioglass^® composite could be a promising material for labrum implants.

This paper will report the fabrication process and microstructure analysis of fibrous composite incorporating ultra-high molecular weight polyethylene (UHMWPE) fabric, electrospun polycaprolactone (PCL), and bioglass particles. Briefly, electrospinning was performed to form PCL fibre lamination in the surface of UHMWPE fabric. This UHMWPE/PCL material was then bioglass-coated. Sequentially, microstructure of the UHMWPE fabric, UHMWPE/PCL, and UHMWPE/PCL/bioglass was imaged and analysed. The composite showed aligned ultrafine PCL fibres and distribution of bioglass particles in the layer of electrospun PCL. The results of this study provide groundwork for more advanced investigation, as well as development of implant prototype.

Giripeni Village is one of the villages in Wates District, Kulon Progo Regency. Giripeni village is on the outskirts of the city, the area is mostly rice fields. Most of the people work as farmers and breeders. The availability of abundant foodstuffs such as grass and secondary crops is used to raise livestock. Giripeni Village has a lot of potential that can be developed, so that it becomes a tourist village to attract the wider community, both nationwide and worldwide from Giripeni Village. The development of this tourism village is one of the rural tourism developments which is expected to become a sustainable tourism development in accordance with government policies in the tourism sector. On the other hand, during the Covid-19 epidemic, many workers lost their jobs and some required workers to do their work from home. Group 88 provides video on using coconut fruit, so that people in Giripeni village whose jobs are affected by the Covid-19 pandemic can remain productive even at home. The method provided to process the coconut involves a simple steps and efficient use of materials. The research was carried out through online observation. The data in this study are secondary data obtained from the Giripeni village website and secondary data obtained based on previous research

Recent shifts in higher education have prompted many universities to adopt new instructional environments, notably hybrid learning models. However, researchers have identified that navigating these hybrid systems can induce significant stress among students. Given that internal personal resources, particularly spirituality, are recognized as vital coping mechanisms for academic stress in highly religious societies, they have significant potential to buffer these negative impacts. Consequently, this study aimed to explore the spiritual experiences of Industrial Engineering students and investigate their correlation with burnout levels within a hybrid learning framework. An online survey was administered to 98 undergraduate students in the Industrial Engineering Department at Universitas Atma Jaya Yogyakarta between February and March 2022. Reliability analysis using Cronbach’s alpha confirmed the internal consistency of the survey instruments for this cohort. A MANOVA revealed significant differences in the Spiritual Index between gender groups and significant variations in burnout levels across academic years. Correlation analyses revealed a significant negative association specifically between spiritual levels and the loss of academic efficacy (r = -0.264; p-value < .05). While general negative trends were also observed with overall burnout, emotional exhaustion, and cynicism, these particular correlations were not statistically significant. The findings suggest that strong spiritual experiences can foster greater life satisfaction, mitigating burnout. Overall, the students exhibited moderate levels of burnout during their hybrid learning experience. It can be concluded that a robust sense of spirituality may help bolster self-esteem and serve as a protective factor against burnout in hybrid educational settings. These findings imply that higher education institutions should proactively integrate student wellness programs that accommodate spiritual and social experiences to effectively mitigate the risk of burnout during hybrid learning transitions.