Introduction: suspected cases of type 2 circulating poliovirus were reported from the Somali, Sidama, and Southern Nations, Nationalities, and Peoples' (SNNP) regions of Ethiopia. A surveillance and laboratory investigation team were deployed to Bokh Woreda, Dollo Zone, Somali Region, for a prompt investigation of the polio outbreak. Four cases, including the index case, tested positive for type 2 circulating poliovirus. The objective of this study was to review the overall polio outbreak response in Ethiopia, validate existing capacity, document best practices, and identify areas for improvement to further strengthen emergency preparedness, surveillance, and future response efforts. Methods: the study employed a qualitative research approach with thematic analysis and used purposive sampling. Results: the study reveals that coordination among various levels of government and non-governmental organizations played a critical role in managing the outbreak. As noted by a key informant, “for the polio coordination, we had revitalized the existing task forces that were previously established for the Measles outbreak campaign” [KII SNNPR Zonal EPI focal, 2020]. The Emergency Operation Center was central in guiding and directing the response, with its five key functions ensuring coordination, logistics, command, planning, and finance [KII Somali Region PHI Director, 202]. Conclusion: effective coordination and preparedness are vital in managing public health emergencies such as the poliomyelitis outbreak in Ethiopia. While the revitalization of existing task forces and the leadership of the Emergency Operation Center facilitated a coordinated response with strong stakeholder engagement, challenges in surveillance and case detection remained significant barriers to optimal outbreak management.