Ekaterina Petrovna Otsupko

Ms. Ekaterina Petrovna Otsupko

orcid

Research Focus & Metrics

Academic Career Length

3Years (2024-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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3 November 2024 in Gels
Verified
Journal Article
Open access
PDF file
MSMikhail Savelyev
Mikhail Savelyev
AKArtem V. Kuksin
Artem V. Kuksin
DMDenis Tarasovich Murashko
Denis Tarasovich Murashko
EOEkaterina Petrovna Otsupko
Ekaterina Petrovna Otsupko
UKUliana E. Kurilova Kurilova
Uliana E. Kurilova Kurilova
Alexander GerasimenkoAlexander Gerasimenko
Alexander Gerasimenko
Currently, tissue engineering technologies are promising for the restoration of damaged organs and tissues. For regeneration of electrically conductive tissues or neural interfaces, it is necessary to provide electrical conductivity for the transmission of electrophysiological signals. The developed biocomposite structures presented in this article possess such properties. Their composition includes bovine serum albumin (BSA), gelatin, eosin-Y and single-walled carbon nanotubes (SWCNTs). For the first time, a biocomposite structure was formed from the proposed hydrogel using a nanosecond laser, and a two-photon absorption cross section value of 580 GM was achieved. Increased viscosity over 3 mPa∙s and self-focusing with a nonlinear refractive index of 42 × 10−12 cm2/W make it possible to create a biocomposite structure over the entire specified area. The obtained electrical conductivity value was 19 mS∙cm−1, due to the formation of effective electrically conductive networks. For a biocomposite with a concentration of gelatin 3 wt. %, formed by low-energy near-IR pulses, the survival of Neuro 2A nerve tissue cells was confirmed. The obtained results are important for the creation of new tissue engineering structures and neural interfaces from a biopolymer hydrogel based on the organic dye eosin-Y and carbon nanotubes by two-photon polymerization.