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Kazuya Yoshida
Department of Oral and Maxillofacial Surgery, National Hospital Organization, Kyoto Medical Center, Kyoto, Japan

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Original article
Published: 06 May 2021 in Clinical Oral Investigations
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Oromandibular dystonia is a focal dystonia characterized by sustained or intermittent contractions of the masticatory and/or tongue muscles. This epidemiological study aimed to estimate the prevalence and incidence of oromandibular dystonia in Kyoto (population: 1,465,701). The population sample was citizens of Kyoto who visited our department between 2015 and 2019 and were differentially diagnosed by an oromandibular dystonia specialist having idiopathic (primary) and acquired (secondary) oromandibular dystonia. A total of 144 patients (100 women and 44 men; mean age, 57.5 years) were analyzed for clinical features, and the prevalence (prevalence date, January 1, 2020) and annual incidence were estimated. The male-to-female ratio was 1:2.3 (p<0.001). Age at onset was significantly (p<0.01) earlier in men (47.5 years) than that in women (56.9 years). The crude prevalence of oromandibular dystonia was estimated at 9.8 per 100,000 persons (95% confidence interval: 8.3–11.6) (idiopathic dystonia, 5.7 [4.6–7.1]; tardive dystonia, 3.4 [2.5–4.5]) and incidence at 2.0 (1.3–2.8) per 100,000 person-years (idiopathic dystonia, 1.2 [0.68–1.9], tardive dystonia, 0.68 [0.32–1.3]). The prevalence was 13.0 (10.5–15.8) in women and 6.3 (4.6–8.5) in men. All age groups showed female predominance. The highest prevalence was 23.6 (14.4–36.5) in women aged 60–69 years. As this is an oral and maxillofacial surgery service–based study, the actual prevalence of oromandibular dystonia may be even higher. It was suggested that oromandibular dystonia might be more common than cervical dystonia or blepharospasm.

ACS Style

Kazuya Yoshida. Prevalence and incidence of oromandibular dystonia: an oral and maxillofacial surgery service–based study. Clinical Oral Investigations 2021, 1 -10.

AMA Style

Kazuya Yoshida. Prevalence and incidence of oromandibular dystonia: an oral and maxillofacial surgery service–based study. Clinical Oral Investigations. 2021; ():1-10.

Chicago/Turabian Style

Kazuya Yoshida. 2021. "Prevalence and incidence of oromandibular dystonia: an oral and maxillofacial surgery service–based study." Clinical Oral Investigations , no. : 1-10.

Observational study
Published: 17 January 2019 in Toxins
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Lingual dystonia is a debilitating type of oromandibular dystonia characterized by involuntary, often task-specific, contractions of the tongue muscle activated by speaking or eating. Botulinum neurotoxin (BoNT) has been used to treat lingual dystonia; however, it is known to cause serious complications, such as dysphasia and aspiration. The purpose of this study was to evaluate the efficacy and adverse effects of individualized BoNT therapy for lingual dystonia. One-hundred-and-seventy-two patients (102 females and 70 males, mean age: 46.2 years) with lingual dystonia were classified into four subtypes based on symptoms of involuntary tongue movements: protrusion (68.6%), retraction (16.9%), curling (7.6%), and laterotrusion (7.0%). Patients were treated with BoNT injection into the genioglossus and/or intrinsic muscles via individualized submandibular and/or intraoral routes. Results were compared before and after BoNT therapy. Botulinum neurotoxin was injected in 136 patients (mean: 4.8 injections). Clinical sub-scores (mastication, speech, pain, and discomfort) in a disease-specific rating scale were reduced significantly (p < 0.001) after administration. Comprehensive improvement after BoNT injection, assessed using the rating scale, was 77.6%. The curling type (81.9%) showed the greatest improvement, while the retraction type showed the least improvement (67.9%). Mild and transient dysphasia occurred in 12.5% of patients (3.7% of total injections) but disappeared spontaneously within several days to two weeks. No serious side effects were observed. With careful diagnosis of subtypes and a detailed understanding of lingual muscle anatomy, individualized BoNT injection into dystonic lingual muscles can be effective and safe.

ACS Style

Kazuya Yoshida. Botulinum Neurotoxin Therapy for Lingual Dystonia Using an Individualized Injection Method Based on Clinical Features. Toxins 2019, 11, 51 .

AMA Style

Kazuya Yoshida. Botulinum Neurotoxin Therapy for Lingual Dystonia Using an Individualized Injection Method Based on Clinical Features. Toxins. 2019; 11 (1):51.

Chicago/Turabian Style

Kazuya Yoshida. 2019. "Botulinum Neurotoxin Therapy for Lingual Dystonia Using an Individualized Injection Method Based on Clinical Features." Toxins 11, no. 1: 51.

Original article
Published: 02 May 2018 in Clinical Oral Investigations
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Oromandibular dystonia, which is characterized by stereotypic, task-specific, or sustained contractions of masticatory and/or lingual muscles, is frequently misdiagnosed as temporomandibular disorders or psychogenic disease. Diagnostic delay in oromandibular dystonia is not acceptable; thus, a screening tool that can distinguish this condition from a temporomandibular disorder may be helpful for medical professionals unfamiliar with involuntary movements or temporomandibular disorders. A questionnaire that included questions on the clinical features of oromandibular dystonia, such as stereotypy, task-specificity, sensory tricks, and morning benefit, and included questions to rule out temporomandibular disorders (total point range 0–40) was administered to 553 patients suspected to have involuntary movements. Based on a careful examination and the differential diagnosis, the patients were divided into four groups: oromandibular dystonia (n = 385), oral dyskinesia (n = 84), psychogenic (functional) movement disorder (n = 50), and temporomandibular disorders (n = 34). The questionnaire had a high level of internal consistency as measured by the Cronbach’s α (0.91), and item-total correlation was significant (p < 0.001). The test-retest reliability on two separate occasions showed a significant correlation (p < 0.001). Mean total scores of the questionnaire significantly differed among oromandibular dystonia (32.0), temporomandibular disorders (10.4; one-way analysis of variance, p < 0.001), oral dyskinesia (21.0; p < 0.001), and psychogenic (functional) movement disorder (13.7; p < 0.001). Findings of this study suggest that the present questionnaire is a simple diagnostic tool that is useful for tentative differentiation of oromandibular dystonia from temporomandibular disorders. This screening tool can be used to distinguish oromandibular dystonia from temporomandibular disorders.

ACS Style

Kazuya Yoshida. Oromandibular dystonia screening questionnaire for differential diagnosis. Clinical Oral Investigations 2018, 23, 405 -411.

AMA Style

Kazuya Yoshida. Oromandibular dystonia screening questionnaire for differential diagnosis. Clinical Oral Investigations. 2018; 23 (1):405-411.

Chicago/Turabian Style

Kazuya Yoshida. 2018. "Oromandibular dystonia screening questionnaire for differential diagnosis." Clinical Oral Investigations 23, no. 1: 405-411.

Clinical trial
Published: 25 April 2018 in Toxins
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The aim of this study was to compare treatment outcomes following intramuscular injection of botulinum neurotoxin (BoNT) in patients with recurrent temporomandibular joint dislocation, with and without muscle hyperactivity due to neurological diseases. Thirty-two patients (19 women and 13 men, mean age: 62.3 years) with recurrent temporomandibular joint dislocation were divided into two groups: neurogenic (8 women and 12 men) and habitual (11 women and 1 man). The neurogenic group included patients having neurological disorders, such as Parkinson’s disease or oromandibular dystonia, that are accompanied by muscle hyperactivity. BoNT was administered via intraoral injection to the inferior head of the lateral pterygoid muscle. In total, BoNT injection was administered 102 times (mean 3.2 times/patient). The mean follow-up duration was 29.5 months. The neurogenic group was significantly (p < 0.001) younger (47.3 years) than the habitual group (84.8 years) and required significantly (p < 0.01) more injections (4.1 versus 1.7 times) to achieve a positive outcome. No significant immediate or delayed complications occurred. Thus, intramuscular injection of BoNT into the lateral pterygoid muscle is an effective and safe treatment for habitual temporomandibular joint dislocation. More injections are required in cases of neurogenic temporomandibular joint dislocation than in those of habitual dislocation without muscle hyperactivity.

ACS Style

Kazuya Yoshida. Botulinum Neurotoxin Injection for the Treatment of Recurrent Temporomandibular Joint Dislocation with and without Neurogenic Muscular Hyperactivity. Toxins 2018, 10, 174 .

AMA Style

Kazuya Yoshida. Botulinum Neurotoxin Injection for the Treatment of Recurrent Temporomandibular Joint Dislocation with and without Neurogenic Muscular Hyperactivity. Toxins. 2018; 10 (5):174.

Chicago/Turabian Style

Kazuya Yoshida. 2018. "Botulinum Neurotoxin Injection for the Treatment of Recurrent Temporomandibular Joint Dislocation with and without Neurogenic Muscular Hyperactivity." Toxins 10, no. 5: 174.

Journal article
Published: 01 April 2018 in Journal of Prosthodontic Research
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The sensory trick splint is especially helpful for patients with jaw closing dystonia. It is useful, although partially effective, as an alternative therapy in patients for whom other therapies have been unsatisfactory.

ACS Style

Kazuya Yoshida. Sensory trick splint as a multimodal therapy for oromandibular dystonia. Journal of Prosthodontic Research 2018, 62, 239 -244.

AMA Style

Kazuya Yoshida. Sensory trick splint as a multimodal therapy for oromandibular dystonia. Journal of Prosthodontic Research. 2018; 62 (2):239-244.

Chicago/Turabian Style

Kazuya Yoshida. 2018. "Sensory trick splint as a multimodal therapy for oromandibular dystonia." Journal of Prosthodontic Research 62, no. 2: 239-244.

Journal article
Published: 30 March 2018 in Neurology International
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Oromandibular dystonia is a focal dystonia that manifests as involuntary masticatory and/or tongue muscle contractions. This movement disorder is frequently misdiagnosed as a temporomandibular disorder. Hence, it would be useful to establish a method that makes it possible for patients with the condition to find appropriate medical institutions by themselves. The author produced a website Involuntary movements of the stomatognathic region (https://sites. google.com/site/oromandibulardystoniaenglish/) for patients with oromandibular dystonia, which is available in twenty languages. It has been viewed more than 1,000,000 times by individuals from all over the world. The visitors to the site have completed questionnaires and/or sent images or videos of their involuntary movements over the internet. Cyberconsultations (remote diagnosis) were also performed via Skype™. Approximately 1000 patients with involuntary stomatognathic movements visited our department. Only 12.5% of the patients had previously been diagnosed with or were suspected to have dystonia. The findings of this study suggest that the multilingual website has contributed to increasing awareness of oromandibular dystonia and that the provision of basic telemedicine via the internet can aid the diagnosis and treatment of oromandibular dystonia.

ACS Style

Kazuya Yoshida. Multilingual Website and Cyberconsultations for Oromandibular Dystonia. Neurology International 2018, 10, 45 -50.

AMA Style

Kazuya Yoshida. Multilingual Website and Cyberconsultations for Oromandibular Dystonia. Neurology International. 2018; 10 (1):45-50.

Chicago/Turabian Style

Kazuya Yoshida. 2018. "Multilingual Website and Cyberconsultations for Oromandibular Dystonia." Neurology International 10, no. 1: 45-50.

Original research article
Published: 11 December 2017 in Frontiers in Neurology
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Background: Lingual dystonia is a subtype of oromandibular dystonia, which is a movement disorder characterized by involuntary sustained or intermittent contraction of the masticatory and/or tongue muscles. Lingual dystonia interferes with important daily activities, such as speaking, chewing, and swallowing, resulting in vocational and social disability. Objective: The aim of this study was to investigate a possible relationship between occupation and the development of lingual dystonia. Methods: Phenomenological and clinical characteristics of 95 patients [53 females (55.8%) and 42 males (44.2%), mean age 48.0 years] with task-specific, speech-induced lingual dystonia were analyzed. Structured interviews were carried out to obtain information regarding primary occupation, including overtime work and stress during work. The factors that might have influenced the development of lingual dystonia were estimated using multivariate logistic regression analysis of the 95 patients with lingual dystonia and 95 controls [68 females (71.6%) and 27 males (28.4%), mean age 47.2 years] with temporomandibular disorders. Results: Overall, 84.2% of the patients had regular occupations; 73.8% of the patients with regular occupations reported working overtime more than twice a week, and 63.8% of them experienced stress at the workplace. Furthermore, 82.1% of the patients had engaged in occupations that required them to talk to customers or other people under stressful situations over prolonged periods of time for many years (mean: 15.6 years). The most common occupation was sales representative (17.9%), followed by telephone operator (13.7%), customer service representative (10.5%), health care worker (9.5%), waiter or waitress (5.3%), receptionist (5.3%), and cashier (5.3%). Twenty-nine patients (30.5%) had tardive lingual dystonia. Logistic regression analyses revealed that frequent requirements for professional speaking (p = 0.011, odds ratio: 5.66), high stress during work (p = 0.043, odds ratio: 5.4), and neuroleptic use (p = 0.032, odds ratio: 2.52) were significant contributors to the manifestation of lingual dystonia. Conclusion: Professions in which conversations in stressful situations are unavoidable may trigger lingual dystonia. Therefore, speech-induced lingual dystonia can be regarded as occupational dystonia in certain cases.

ACS Style

Kazuya Yoshida. Clinical and Phenomenological Characteristics of Patients with Task-Specific Lingual Dystonia: Possible Association with Occupation. Frontiers in Neurology 2017, 8, 1 .

AMA Style

Kazuya Yoshida. Clinical and Phenomenological Characteristics of Patients with Task-Specific Lingual Dystonia: Possible Association with Occupation. Frontiers in Neurology. 2017; 8 ():1.

Chicago/Turabian Style

Kazuya Yoshida. 2017. "Clinical and Phenomenological Characteristics of Patients with Task-Specific Lingual Dystonia: Possible Association with Occupation." Frontiers in Neurology 8, no. : 1.

Article
Published: 14 December 2016 in Movement Disorders Clinical Practice
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View Supplementary Video Oromandibular dystonia is a focal dystonia that manifests as involuntary masticatory and/or tongue muscle contractions. Jaw opening, jaw deviation, and jaw protrusion types of oromamdibular dystonia are caused by involuntary contraction of the lateral pterygoid muscles. The medial pterygoid can be very hyperactive in jaw closing dystonia as a result of the so-called “whack-a-mole phenomenon,” after repeated botulinum toxin injections into the masseter and temporalis muscles. The more accurately the botulinum toxin is injected into the muscles, the more likely the improvement in the patient's symptoms, and the lower the risk of complications, such as hematoma or arterial bleeding. Both pterygoid muscles can be accessed by intra- and extraoral routes. Safe and correct injection of botulinum toxin into both pterygoid muscles is described in this video. With understanding of the anatomy of the muscles, indications for injection, and technique of needle placement, injection of botulinum toxin into the lateral and medial pterygoid muscles is safe and effective for oromandibular dystonia.

ACS Style

Kazuya Yoshida. How Do I Inject Botulinum Toxin Into the Lateral and Medial Pterygoid Muscles? Movement Disorders Clinical Practice 2016, 4, 285 -285.

AMA Style

Kazuya Yoshida. How Do I Inject Botulinum Toxin Into the Lateral and Medial Pterygoid Muscles? Movement Disorders Clinical Practice. 2016; 4 (2):285-285.

Chicago/Turabian Style

Kazuya Yoshida. 2016. "How Do I Inject Botulinum Toxin Into the Lateral and Medial Pterygoid Muscles?" Movement Disorders Clinical Practice 4, no. 2: 285-285.

Journal article
Published: 28 October 2016 in Journal of Cranio-Maxillofacial Surgery
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It was suggested that coronoidotomy is useful for patients with jaw closing dystonia accompanied by trismus in whom other therapies are ineffective.

ACS Style

Kazuya Yoshida. Surgical intervention for oromandibular dystonia-related limited mouth opening: Long-term follow-up. Journal of Cranio-Maxillofacial Surgery 2016, 45, 56 -62.

AMA Style

Kazuya Yoshida. Surgical intervention for oromandibular dystonia-related limited mouth opening: Long-term follow-up. Journal of Cranio-Maxillofacial Surgery. 2016; 45 (1):56-62.

Chicago/Turabian Style

Kazuya Yoshida. 2016. "Surgical intervention for oromandibular dystonia-related limited mouth opening: Long-term follow-up." Journal of Cranio-Maxillofacial Surgery 45, no. 1: 56-62.

Journal article
Published: 01 July 2016 in Journal of Oral and Maxillofacial Surgery
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Somatosensory evoked fields (SEFs) induced by tongue stimulation can be useful as an objective parameter to assess sensory disturbances in the tongue. However, whether tongue SEFs can be useful as a clinical, objective follow-up assessment method of tongue sensation after oral surgery is unknown. We describe 2 cases in which tongue SEFs were successfully used in clinical assessment. Two patients with unilateral tongue sensory deficits caused by lingual nerve injury during lower third molar extraction were recruited. Both patients underwent surgery to repair the damaged nerve, and all tongue sensory evaluations were performed once before and once after surgery. SEFs were recorded by stimulating the affected and unaffected sides of the tongue separately, and cortical activity was evaluated over the contralateral hemisphere. The unilaterality of the deficit also was assessed. In both patients, stimulation of the unaffected side evoked reproducible cortical responses before and after surgery. Both patients also recovered some sensation after surgery, given that presurgery stimulation of the affected side failed to evoke cortical activity whereas postsurgery stimulation evoked cortical activity on both sides. Sensation was initially highly lateralized in both patients but was restored to approximately normal in the postsurgery evaluation. Finally, both patients rated their subjective tongue sensations on the affected side over 50% better after the surgical intervention. These cases indicate that tongue SEFs may have a clinical use as an objective parameter for assessing the course of tongue sensory recovery.

ACS Style

Hitoshi Maezawa; Itaru Tojyo; Kazuya Yoshida; Shigeyuki Fujita. Recovery of Impaired Somatosensory Evoked Fields After Improvement of Tongue Sensory Deficits With Neurosurgical Reconstruction. Journal of Oral and Maxillofacial Surgery 2016, 74, 1473 -1482.

AMA Style

Hitoshi Maezawa, Itaru Tojyo, Kazuya Yoshida, Shigeyuki Fujita. Recovery of Impaired Somatosensory Evoked Fields After Improvement of Tongue Sensory Deficits With Neurosurgical Reconstruction. Journal of Oral and Maxillofacial Surgery. 2016; 74 (7):1473-1482.

Chicago/Turabian Style

Hitoshi Maezawa; Itaru Tojyo; Kazuya Yoshida; Shigeyuki Fujita. 2016. "Recovery of Impaired Somatosensory Evoked Fields After Improvement of Tongue Sensory Deficits With Neurosurgical Reconstruction." Journal of Oral and Maxillofacial Surgery 74, no. 7: 1473-1482.

Journal article
Published: 13 September 2013 in Clinical Neurophysiology
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To evaluate lip sensory dysfunction in patients with inferior alveolar nerve injury by lip-stimulated somatosensory evoked fields (SEFs). SEFs were recorded following electrical lip stimulation in 6 patients with unilateral lip sensory disturbance and 10 healthy volunteers. Lip stimulation was applied non-invasively to each side of the lip with the same intensity using pin electrodes. All healthy volunteers showed the earliest response clearly and consistently at around 25 ms (P25m) and at least one of the following components, P45m, P60m, or P80m, over the contralateral hemisphere. The ranges of the peak latencies were 23–33, 42–50, 56–67, and 72–98 ms for right-side stimulation and 23–34, 46–49, 52–68, and 71–90 ms for left-side stimulation. Affected-side stimulation did not evoke P25m component in any patients, but invoked traceable responses in 5 patients whose latencies were 57, 89, 65, 53, and 54 ms. Unaffected-side stimulation induced P25m in 2 patients at 27 and 25 ms, but not in the other 4 patients. The P25m component of lip SEFs can be an effective parameter to indicate lip sensory abnormality. Lip sensory dysfunction can be objectively evaluated using magnetoencephalography.

ACS Style

Hitoshi Maezawa; Masao Matsuhashi; Kazuya Yoshida; Tatsuya Mima; Takashi Nagamine; Hidenao Fukuyama. Evaluation of lip sensory disturbance using somatosensory evoked magnetic fields. Clinical Neurophysiology 2013, 125, 363 -369.

AMA Style

Hitoshi Maezawa, Masao Matsuhashi, Kazuya Yoshida, Tatsuya Mima, Takashi Nagamine, Hidenao Fukuyama. Evaluation of lip sensory disturbance using somatosensory evoked magnetic fields. Clinical Neurophysiology. 2013; 125 (2):363-369.

Chicago/Turabian Style

Hitoshi Maezawa; Masao Matsuhashi; Kazuya Yoshida; Tatsuya Mima; Takashi Nagamine; Hidenao Fukuyama. 2013. "Evaluation of lip sensory disturbance using somatosensory evoked magnetic fields." Clinical Neurophysiology 125, no. 2: 363-369.

Evaluation study
Published: 30 November 2011 in Neuroscience Research
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Quantitative measurement is required in clinical situation for sensory disturbance of the tongue due to lingual nerve injury. To assess disabled sensory function of the tongue, somatosensory evoked magnetic fields (SEFs) were measured following electric tongue stimulation in 13 patients with sensory disturbance by unilateral lingual nerve injury and in 10 age-matched healthy volunteers. Affected- and healthy-sides of the tongue were stimulated separately with the same intensity. Although the healthy-side stimulation induced clear responses over the contralateral hemisphere of all participants, the affected-side stimulation evoked hardly traceable responses in 6 patients and no activity in the remaining 7 patients. We evaluated the cortical activity via activated root-mean-square (aRMS), which is the time-averaged activity between 10 and 150 ms from the 18-channel RMS over the contralateral hemisphere. The laterality index of aRMS, expressed as [(left − right)/(left + right)], was out of the pre-defined normal range (−0.287 to 0.337) in 12 patients, and within the range in all healthy volunteers. The test sensitivity and specificity of the procedure were 92.3% and 100%, respectively. Tongue SEFs are reproducible and objective method to evaluate sensory disturbance of the tongue.

ACS Style

Hitoshi Maezawa; Kazuya Yoshida; Masao Matsuhashi; Yohei Yokoyama; Tatsuya Mima; Kazuhisa Bessho; Shigeyuki Fujita; Takashi Nagamine; Hidenao Fukuyama. Evaluation of tongue sensory disturbance by somatosensory evoked magnetic fields following tongue stimulation. Neuroscience Research 2011, 71, 244 -250.

AMA Style

Hitoshi Maezawa, Kazuya Yoshida, Masao Matsuhashi, Yohei Yokoyama, Tatsuya Mima, Kazuhisa Bessho, Shigeyuki Fujita, Takashi Nagamine, Hidenao Fukuyama. Evaluation of tongue sensory disturbance by somatosensory evoked magnetic fields following tongue stimulation. Neuroscience Research. 2011; 71 (3):244-250.

Chicago/Turabian Style

Hitoshi Maezawa; Kazuya Yoshida; Masao Matsuhashi; Yohei Yokoyama; Tatsuya Mima; Kazuhisa Bessho; Shigeyuki Fujita; Takashi Nagamine; Hidenao Fukuyama. 2011. "Evaluation of tongue sensory disturbance by somatosensory evoked magnetic fields following tongue stimulation." Neuroscience Research 71, no. 3: 244-250.

Research article
Published: 01 April 2009 in CRANIO®
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A shortened dental arch without posterior occlusal support has been thought to maintain sufficient oral function. The mechanism of occlusal adaptation with a shortened dental arch is unclear. For a better understanding of the effects of molar teeth on brain function, the authors combined experimentally- shortened dental arches and a neuro-imaging technique. Regional cerebral blood volume was measured using near-infrared optical topography during maximum voluntary clenching tasks from 10 subjects on individually fabricated oral appliances, which can create experimentally complete and shortened dental arches. Results suggested that clenching on the complete dental arch showed a significantly higher brain blood volume than that on the shortened dental arch. Moreover, there were no differences between the two splints in the latency to the maximum oxyhemoglobin concentration. These findings suggest that occlusal status is closely related to brain blood flow and lack of occlusal molar support rapidly reduces cerebral blood volume in the maximum voluntary clenching condition.

ACS Style

Ikuya Miyamoto; Kazuya Yoshida; Kazuhisa Bessho. Shortened Dental Arch and Cerebral Regional Blood Volume: An Experimental Pilot Study with Optical Topography. CRANIO® 2009, 27, 94 -100.

AMA Style

Ikuya Miyamoto, Kazuya Yoshida, Kazuhisa Bessho. Shortened Dental Arch and Cerebral Regional Blood Volume: An Experimental Pilot Study with Optical Topography. CRANIO®. 2009; 27 (2):94-100.

Chicago/Turabian Style

Ikuya Miyamoto; Kazuya Yoshida; Kazuhisa Bessho. 2009. "Shortened Dental Arch and Cerebral Regional Blood Volume: An Experimental Pilot Study with Optical Topography." CRANIO® 27, no. 2: 94-100.

Journal article
Published: 28 November 2007 in Journal of Prosthodontics
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Maintenance of healthy periimplant soft tissue is a significant problem for orbital prosthesis wearers. Two female patients with orbital defects after malignant tumor resection were treated using custom‐made retentive components of an individual magnet for an Epitec System orbital prosthesis. Freestanding hygienic retentive components for an individual magnet were fabricated. An abutment replica was trimmed and modified, and using pattern resin, a magnetic keeper was cast and soldered to the abutment. The patients could maintain good hygiene and healthy periimplant soft tissue. This type of freestanding retentive component may be advantageous for the hygiene maintenance of periimplant soft tissue.

ACS Style

Kazuya Yoshida; Akira Takagi; Yoichi Tsuboi; Kazuhisa Bessho. Modified Hygienic Epitec System Abutment for Magnetic Retention of Orbital Prostheses. Journal of Prosthodontics 2007, 17, 219 -222.

AMA Style

Kazuya Yoshida, Akira Takagi, Yoichi Tsuboi, Kazuhisa Bessho. Modified Hygienic Epitec System Abutment for Magnetic Retention of Orbital Prostheses. Journal of Prosthodontics. 2007; 17 (3):219-222.

Chicago/Turabian Style

Kazuya Yoshida; Akira Takagi; Yoichi Tsuboi; Kazuhisa Bessho. 2007. "Modified Hygienic Epitec System Abutment for Magnetic Retention of Orbital Prostheses." Journal of Prosthodontics 17, no. 3: 219-222.

Conference abstract
Published: 28 February 2007 in Sleep Medicine
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ACS Style

Kazuya Yoshida. S21.D Dental devices used during sleep. Sleep Medicine 2007, 8, S26 -26.

AMA Style

Kazuya Yoshida. S21.D Dental devices used during sleep. Sleep Medicine. 2007; 8 ():S26-26.

Chicago/Turabian Style

Kazuya Yoshida. 2007. "S21.D Dental devices used during sleep." Sleep Medicine 8, no. : S26-26.

Conference abstract
Published: 30 September 2006 in Sleep Medicine
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ACS Style

Kazuya Yoshida. P302 Perception of tactile sensation in the soft palate evaluated by somatosensory evoked magnetic fields. Sleep Medicine 2006, 7, S43 -43.

AMA Style

Kazuya Yoshida. P302 Perception of tactile sensation in the soft palate evaluated by somatosensory evoked magnetic fields. Sleep Medicine. 2006; 7 ():S43-43.

Chicago/Turabian Style

Kazuya Yoshida. 2006. "P302 Perception of tactile sensation in the soft palate evaluated by somatosensory evoked magnetic fields." Sleep Medicine 7, no. : S43-43.

Case reports
Published: 01 July 2006 in CRANIO®
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To examine the effects of botulinum toxin injection application for the treatment of upper airway obstruction due to hyperactive lateral pterygoid muscle contraction, we applied botulinum toxin injection. A 20 year-old male patient had involuntary mouth opening after a diabetic coma. His mouth opened excessively (84 mm) particularly when he was in a nervous or stressed condition. This resulted in a bilateral temporomandibular dislocation and, consequently, upper airway collapse. The differential diagnosis of jaw-opening oromandibular dystonia was made. Botulinum toxin type A was bilaterally injected into the lateral pterygoid muscle. The excessive mouth opening was reduced, and the patient showed no temporomandibular joint (TMJ) dislocation or experienced any further airway collapse after the injections. We successfully applied botulinum toxin to a patient with upper airway obstruction and TMJ dislocation relative to jaw-opening dystonia.

ACS Style

Kazuya Yoshida; Tadahiko Iizuka. Botulinum Toxin Treatment for Upper Airway Collapse Resulting from Temporomandibular Joint Dislocation Due to Jaw-Opening Dystonia. CRANIO® 2006, 24, 217 -222.

AMA Style

Kazuya Yoshida, Tadahiko Iizuka. Botulinum Toxin Treatment for Upper Airway Collapse Resulting from Temporomandibular Joint Dislocation Due to Jaw-Opening Dystonia. CRANIO®. 2006; 24 (3):217-222.

Chicago/Turabian Style

Kazuya Yoshida; Tadahiko Iizuka. 2006. "Botulinum Toxin Treatment for Upper Airway Collapse Resulting from Temporomandibular Joint Dislocation Due to Jaw-Opening Dystonia." CRANIO® 24, no. 3: 217-222.

Comparative study
Published: 30 June 2006 in Neuroscience Research
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Impairment of sensory input to the soft palate has been reported in patients with obstructive sleep apnea syndrome. To investigate the reaction in the central nervous system related to soft palate perception, we measured the somatosensory evoked magnetic fields following air-puff stimulation in seven healthy volunteers by using a helmet-shaped 122-channel neuromagnetometer. The air-puffs were produced using compressed nitrogen and directed to the middle of the soft palate with an intraoral device. To evaluate the laterality of responses we used another appliance in which the air-puffs were directed to the middle and right side of the soft palate. In all the subjects, responses were identified symmetrically in the bilateral parietotemporal regions with a mean latency of about 130 ms from the soft palate stimulation. Prior to this peak, no distinct early responses were observed. There was no significant difference in the responses between the middle and right side stimulation. Corresponding equivalent current dipoles were estimated around the Sylvian fissures. These results suggested that the responses were derived from the second somatosensory areas. In conclusion, we could record long-latency responses to air-puff stimulation of the soft palate in the bilateral second somatosensory areas.

ACS Style

Kazuya Yoshida; Hitoshi Maezawa; Takashi Nagamine; Hidenao Fukuyama; Kenichiro Murakami; Tadahiko Iizuka. Somatosensory evoked magnetic fields to air-puff stimulation on the soft palate. Neuroscience Research 2006, 55, 116 -122.

AMA Style

Kazuya Yoshida, Hitoshi Maezawa, Takashi Nagamine, Hidenao Fukuyama, Kenichiro Murakami, Tadahiko Iizuka. Somatosensory evoked magnetic fields to air-puff stimulation on the soft palate. Neuroscience Research. 2006; 55 (2):116-122.

Chicago/Turabian Style

Kazuya Yoshida; Hitoshi Maezawa; Takashi Nagamine; Hidenao Fukuyama; Kenichiro Murakami; Tadahiko Iizuka. 2006. "Somatosensory evoked magnetic fields to air-puff stimulation on the soft palate." Neuroscience Research 55, no. 2: 116-122.

Case reports
Published: 21 March 2006 in Movement Disorders
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Oromandibular dystonia is a focal dystonia involving the masticatory and/or tongue muscles. This report describes 2 female patients with jaw‐closing dystonia treated by surgical resection of the coronoid process. The patients could not open their mouths due to involuntary jaw‐closing muscle contraction. We first treated them by injecting lidocaine and alcohol (muscle afferent block) into the masseter and temporal muscles and then botulinum toxin. However, the trismus improved mildly and transitorily. Therefore, coronoidotomy was done under general anesthesia. The jaw opening increased to 50 mm. Coronoidotomy is useful for patients with jaw‐closing dystonia in whom other therapies are ineffective. © 2006 Movement Disorder Society

ACS Style

Kazuya Yoshida. Coronoidotomy as treatment for trismus due to jaw-closing oromandibular dystonia. Movement Disorders 2006, 21, 1028 -1031.

AMA Style

Kazuya Yoshida. Coronoidotomy as treatment for trismus due to jaw-closing oromandibular dystonia. Movement Disorders. 2006; 21 (7):1028-1031.

Chicago/Turabian Style

Kazuya Yoshida. 2006. "Coronoidotomy as treatment for trismus due to jaw-closing oromandibular dystonia." Movement Disorders 21, no. 7: 1028-1031.

Journal article
Published: 17 February 2006 in The International Journal of Prosthodontics
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ACS Style

Kazuya Yoshida. Effect on blood pressure of oral appliance therapy for sleep apnea syndrome. The International Journal of Prosthodontics 2006, 19, 61 -6.

AMA Style

Kazuya Yoshida. Effect on blood pressure of oral appliance therapy for sleep apnea syndrome. The International Journal of Prosthodontics. 2006; 19 (1):61-6.

Chicago/Turabian Style

Kazuya Yoshida. 2006. "Effect on blood pressure of oral appliance therapy for sleep apnea syndrome." The International Journal of Prosthodontics 19, no. 1: 61-6.