• Half of participants perceived some weight gain during staying at home measures. • One third perceived that their overall diet became less healthy with home confinement. • The reduction in exercise time was significantly associated with weight gain. • Increase in setting/reclining, and screen times were significantly associated with weight gain.

Some studies have reported that influenza vaccination is associated with lower risk of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and/or coronavirus disease 2019 (COVID-19) morbidity and mortality. This study aims to estimate effectiveness of influenza vaccination, using Abbott's quadrivalent Influvac Tetra vaccine, against SARS-CoV-2 infection and against severe COVID-19. This matched, test-negative, case-control study was implemented on a population of 30,774 healthcare workers (HCWs) in Qatar during the 2020 annual influenza vaccination campaign, September 17, 2020-December 31, 2020, before introduction of COVID-19 vaccination. Of 30,774 HCWs, 576 with PCR-positive tests and 10,033 with exclusively PCR-negative tests were eligible for inclusion in the study. Matching by sex, age, nationality, reason for PCR testing, and PCR test date yielded 518 cases matched to 2058 controls. Median duration between influenza vaccination and the PCR test was 43 days (IQR, 29-62). Estimated effectiveness of influenza vaccination against SARS-CoV-2 infection> 14 days after receiving the vaccine was 29.7% (95% CI: 5.5-47.7%). Estimated effectiveness of influenza vaccination against severe, critical, or fatal COVID-19 was 88.9% (95% CI: 4.1-98.7%). Sensitivity analyses confirmed the main analysis results. Recent influenza vaccination is associated with a significant reduction in the risk of SARS-CoV-2 infection and COVID-19 severity.

Starting May 6, 2022, a rising number of monkeypox cases started to be detected in different countries where the disease is not endemic. About 24 countries reported cases by May 28 mostly in Europe. Most of the reported cases so far were among young men particularly men who have sex with men or had a travel history to countries where cases are being registered. In this rapid review we summarized the story behind the first few cases of monkeypox virus infection in non-endemic countries and the prevention measures implemented so far by countries to contain the spread of the disease.

The ongoing coronavirus disease 2019 (COVID-19) pandemic has turned into one of the most serious public health crises of the last few decades. Although the disease can result in diverse and multiorgan pathologies, very few studies have addressed the postmortem pathological findings of COVID-19 cases. Active autopsy findings amid this pandemic could be an essential tool for diagnosis, surveillance, and research. We aimed to provide a comprehensive picture of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) histopathological features of different body organs through a systematic review of the published literature. A systematic search of electronic databases (PubMed, ScienceDirect, Google Scholar, medRxiv, and bioRxiv) for journal articles of different study designs reporting postmortem pathological findings in COVID-19 cases was performed. The Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines were used for conducting the review. A total of 50 articles reporting 430 cases were included in our analysis. Postmortem pathological findings were reported for different body organs: pulmonary system (42 articles), cardiovascular system (23 articles), hepatobiliary system (22 articles), kidney (16 articles), spleen and lymph nodes (12 articles), and central nervous system (seven articles). In lung samples, diffuse alveolar damage (DAD) was the most commonly reported finding in 239 cases (84.4%). Myocardial hypertrophy (87 cases, 51.2%), arteriosclerosis (121 cases, 62%), and steatosis (118 cases, 59.3%) were the most commonly reported pathological findings in the heart, kidney, and the hepatobiliary system respectively. Autopsy examination as an investigation tool could lead to a better understanding of SARS-CoV-2 pathophysiology, diagnosis, and management, subsequently improving patient care.

Background: Screening for antenatal depression and its determinants is highly recommended. However, there is no consensus on a standard conceptual framework to approach pregnant women in a primary health care setting. The prevalence of antenatal depression and significant determinants are unknown in Qatar, a gap that we propose to fill.Methods: An analytical cross-sectional study with a probability sampling technique was employed. Enrolling eight-hundred participants from primary health care centers. The screening was performed through a valid and reliable screening instrument ‘Edinburgh Postpartum Depression Scale.’ In addition to the proposed Comprehensive Biopsychosocial Model, participants were asked about their predisposing profile, biological risk, and other suggested modifiable variables.Results: Twenty-one percent reported minor depressive episodes (n = 167, 20.9%) at a 95% confidence interval [18.2–23.8]. Previous use of mental health medications, fear of giving birth, concern about appearance, low perceived social support, and low resilience level showed to be associated with antenatal depression. The logistic regression analyses revealed that the Comprehensive Biopsychosocial model forecast 89% of antenatal depression predictors provided Area Under the Receiver Operating Characteristic Curve of 0.89 at a 95% confidence interval [0.85 to 0.92].Conclusions: Antenatal depression is common among pregnant women in Qatar, and preventive interventions must target the determinants revealed. From a clinical perspective, the use of the proposed model may aid in the standardization of the screening process.

To determine the levels of depression, anxiety, and stress among healthcare workers (HCWs) working in a unique male-dominated environment under the umbrella of Qatar Red Crescent, and to explore the associated factors during COVID-19 pandemic in Qatar. a cross-sectional study utilizing a web-based survey was conducted in the period between 15 November 2020 and 22 December 2020. Depression, anxiety, and stress were determined using the 9-items patient health questionnaire (PHQ-9), the 7-item generalized anxiety disorder (GAD-7) scale, and the 22- item impact of event scale revised (IES-R), respectively. We conducted multivariable logistic regression analysis to determine the predictors of mental health outcomes among HCWs. the proportions of the participants reporting symptoms of depression, anxiety, and stress were 12.4 (95%CI: 9.3–16.1), 14.2 (95%CI: 10.9–18.1), and 18.5% (95%CI: 14.8–22.7) respectively. Arabs had significantly more severe anxiety levels than non-Arabs (p = 0.031), HCWs with high COVID-19 risk perception experienced more severe mental health outcomes (p < 0.001). The multivariable logistic regression showed that high risk perception was independently associated with depression (adjusted OR 4.62, 95%CI: 2.00–10.68), anxiety (adjusted OR 4.90, 95%CI: 2.24–10.68), and stress (adjusted OR 3.067, 95%CI: 1.62–5.79) with p < 0.001. Compared to nurses, technicians and paramedics were more likely to report anxiety symptoms with (adjusted OR 2.97, 95%CI: 1.23–7.17, p = 0.015), and (adjusted OR 5.48, 95%CI: 1.86–16.12, p = 0.002) respectively. Having a relative or a friend died of COVID-19 infection was significantly associated with depression symptoms (adjusted OR 2.54, 95%CI: 1.21–5.36, p = 0.014). Not living with family was significantly associated with the presence of different mental health outcomes. relatively lower rates of mental health outcomes in this study compared to others could have several explanations related to the unique characteristics of our target population and their working environment. Ensuring proper mental health support for HCWs is highly recommended.