Bioreactors are crucial for biopharmaceutical engineering, and their properties have an important impact on cell cultivation. Orbitally shaken bioreactors (OSRs) are gradually gaining more and more attention because of their special operational advantages and suitability for disposable cultivation. In this paper, the performance of OSRs is analyzed in comparison to stirred tank bioreactors (STRs). CFD models were established to investigate the difference in fluid dynamics between OSRs and STRs at the same power input levels. The CFD and experiment data showed that mixing and oxygen transfer needed less energy in OSRs than in STRs. Moreover, the shear stress was still at a low level for agitation behaviors in both OSRs and STRs.
To improve the thermal management level of power battery packs for new energy vehicles, a novel cooling plate with vein flow channels was proposed. The vein flow channel structure includes bilaterally symmetrical vein-shaped branches, a dovetail-shaped outlet branch, and a side collecting branch. This study conducted a comparative analysis on the hydrodynamic characteristics, heat transfer performance, and pumping power consumption of the novel cold plate, while investigating the influence of flow channel structure on the working fluid distribution and cooling performance of the liquid cold plate (LCP). The results indicate that the dovetail-shaped outlet branch can significantly enhance the flow distribution capacity of the tail branch channels of the LCP, the side collecting channel can improve the overall flow distribution capacity of the branch channels by reducing flow resistance, and the converging main channel can effectively compensate for the insufficient flow distribution capacity at the front part of the LCP by mitigating the uneven distribution at the tail. Additionally, the results demonstrate that the optimized design achieves a 9.5 °C (21%) reduction in the maximum temperature and a 6.3 °C (32%) reduction in the temperature difference.