The main aim of this work was to determine the impact of COMT and DRD2 gene polymorphisms together with temperament and character traits on alcohol craving severity alcohol-dependent persons. The sample comprised of 89 men and 16 women (aged $38\pm 7$). For the sake of psychological assessment various analytic methods have been applied like the Short Alcohol Dependence Data Questionnaire (SADD), Penn Alcohol Craving Scale (PACS) or Temperament and Character Inventory (TCI) test. The SNP polymorphism of the analyzed genes was determined by Real Time PCR test. The results showed, that the COMT polymorphismmay have an indirected relationship with the intensity and changes in alcohol craving during abstinence. The DRD2 receptor gene polymorphisms are related with the intensity of alcohol craving. It seems that the character traits like “self-targeting”, including “self-acceptance”, are more closely related to the severity of alcohol craving and polymorphic changes in the DRD2 receptor than temperamental traits. Although this is a pilot study the obtained results appeared to be promising and clearly indicate the link betweengene polymorphisms alcohol craving and its severity.

Representatives of helping professions are particularly exposed to occupational stress. The aim of the study was to evaluate mental and physical well-being, as well as their correlates and predictors in a group of employees working at youth educational centres and sociotherapy centres. A total of 96 employees working at youth educational centres and sociotherapy centres in Kujawsko-Pomorskie voivodeship took part in the study. The following psychometric tools were used: the Psychosocial Working Conditions Questionnaire, the Mini-COPE, the LOT-R, and the GSES. The results obtained indicate that people working in helping professions experience mental and physical health problems. Only 3% of the subjects declared they sleep all night. Over 40% and over 35% of the subjects estimate they suffer from low mood and irritation episodes, respectively, rather frequently or continually. Subjects with poorer mental health are more likely to use Helplessness, Avoidance behaviours, or Turning to religion to cope with stress. The strongest predictor of mental well-being is the sense of self-efficacy. Whereas, the strongest predictor of physical well-being is the ability to cope with stress by giving into the feeling of Helplessness. The study demonstrated poor mental and physical well-being of the subjects. A statistically significant correlation was found between sex and the level of mental and physical health. Employees working at youth educational centres and sociotherapy centres with better mental and physical well-being had a stronger sense of self-efficacy and a higher level of life optimism. Hence, the sense of self-efficacy is a predictor for better mental well-being.