This case report details the esthetic rehabilitation of a 32‐year‐old male patient suffering from sleep bruxism, primarily manifesting as a fracture and significant loss of tooth structure in the anterior maxillary central incisors. To address these concerns, the patient underwent a restorative treatment involving the application of semidirect resin composite veneers on the maxillary incisors and direct resin composite restoration on the incisal regions of the maxillary canines. This approach not only restored the functional integrity of the teeth but also significantly enhanced the patient’s esthetic appearance.

This study aimed to develop a sustainable route for processing biogenic calcium carbonate from Perna perna mussel shell waste and converting it into hydroxyapatite (HA), as well as to evaluate its potential for bone and dental tissue engineering applications. Mussel shells were decarbonized (400 °C), milled, and converted to HA via wet chemical precipitation using a nominal Ca/P molar ratio of 1.67 during synthesis followed by thermal treatment (900 °C). Comprehensive characterization included SEM, FTIR, XRD, Raman spectroscopy, XRF, TGA, and BET analysis. Biological evaluation involved cytotoxicity assays (MTT), antimicrobial testing, and odontogenic differentiation studies (Alizarin Red) using SHEDs. Statistical analysis by one-way ANOVA and Tukey post hoc tests (α = 0.05). SEM revealed a microstructured morphology composed of agglomerates, favorable for biomedical applications. FTIR and XRD confirmed the conversion of CaCO₃ to hydroxyapatite, while thermal analysis demonstrated the material’s stability. The HA exhibited secondary minor phase (13%) β-TCP form of calcium phosphate (Ca_2.997H_0.006(PO₄)₂), high crystallinity (about 80%), and nanoscale crystallite size (85 nm, 2.5–5.0 m²/g), despite forming larger agglomerates in suspension. The material showed favorable physicochemical properties (neutral pH, −18.5 mV zeta potential), but no inhibition was detected in antimicrobial testing. In vitro assays showed excellent cytocompatibility (viability > 70% at 12.5 µg/mL) and significant osteogenic potential (high mineralization vs. controls, p < 0.05). Mussel shell-derived HA presents a sustainable, clinically relevant biomaterial with ideal properties for bone regeneration. The study establishes a complete waste-to-biomaterial pipeline while addressing key requirements for dental and orthopedic applications.

Chronic wounds remain locked in persistent inflammation with high microbial burden, demanding dressings that suppress infection without sacrificing biocompatibility. Bacterial nanocellulose (BNC) is an attractive matrix due to its biocompatibility, nanofibrillar architecture, and moisture retention, but it lacks antimicrobial activity. Here, we engineer BNC membranes post-functionalized with functionalized graphite (f-Gr; predominantly graphitic with residual surface groups) and/or niobium pentoxide (Nb₂O₅), and evaluate four groups: BNC (matrix control), BNC/Nb₂O₅, BNC/f-Gr, and BNC/f-Gr/Nb₂O₅. Physicochemical analyses (Raman and Voigt fitting, FTIR-ATR, XRD, and SEM) confirm a graphitic carbon phase and physical incorporation of the modifiers into the BNC network, with a noticeable shift in the hydration/polarity profile—more evident in the presence of f-Gr. In standardized microbiological assays, BNC/f-Gr promoted a moderate, contact-dependent reduction in bacterial proliferation, particularly against Staphylococcus aureus, whereas BNC/Nb₂O₅ behaved similarly to pristine BNC under the tested conditions. The combined f-Gr/Nb₂O₅ formulation showed an intermediate antimicrobial response, with no clear synergy beyond f-Gr alone. Cytotoxicity assays indicated cytocompatibility for BNC, BNC/f-Gr, and BNC/Nb₂O₅; the combined group displayed a slight reduction that remained within acceptable limits. Overall, BNC/f-Gr emerges as the most promising antimicrobial dressing, while Nb₂O₅ did not significantly enhance antimicrobial performance under the tested conditions and warrants further optimization regarding loading and distribution.

Calcium carbonate (CaCO₃) has garnered increasing attention in dental research due to its versatile bioactive properties and expanding applications in preventive, restorative, and regenerative therapies. Objective This study aims to comprehensively assess the bibliometric features of articles evaluating the utilization of calcium carbonate (CaCO₃) in dentistry by conducting a bibliographic search on the Web of Science databases until March 2025. Methodology The following data were collected: number and density of citations; authorship; year, journal of publication, and impact factor; study design and theme; keywords; institution and country of origin. VOSviewer software was used to generate collaborative network maps for authors and keywords. Results A total of 91 highly cited articles were identified, with citation counts ranging from 123 to zero. Most articles (74%) were published after 2010, with the highest prevalence in Asia (44%), especially China (10%). The most frequent study design was in vitro (55%), primarily focused on restorative dentistry (29%) and cariology (23%). The most common keywords were “Calcium Carbonate” and “Hydroxyapatite”. DeVizio W. was the most prolific author, with four publications. Conclusions Bibliometric analysis highlights a growing interest in the application of calcium carbonate in dentistry, with a progressive increase in scientific output over the years. The findings underscore the global distribution of research and emphasize the relevance of this biomaterial in various dental specialties. This study reinforces several key points for research groups worldwide engaged in the development of innovative dental materials, providing valuable direction for future investigations, which remain limited in scope, especially regarding clinical applications and long-term outcomes.