Aedes aegypti is a vector responsible for the transmission of various arboviruses and is considered by the World Health Organization to be one of the main public health problems in the world. This study evaluated the larvicidal and oviposition activity of essential oils from Abies sibirica, Pogostemon cablin and Juniperus communis and their formulations. Chromatographic analysis by GCMS identified a total of 28, 52 and 18 compounds for the oils of the species A. sibirica, J. communis and P. cablin, respectively. The larvicidal bioassays showed an LC₅₀ of 67.53 ppm, 92.45 ppm and 35.95 ppm, respectively, for A. sibirica (A), J. communis (J) and P. cablin (P) as well as their binary (J + P, 39.50 ppm; A + P, 51.64 ppm) and ternary (A + J + P, 66.99 ppm) formulations. These oils and formulations also showed deterrent activity at the larvicidal concentrations tested (A. sibirica: OAI: −0.41; J. communis: OAI: −0.31; P. cablin: OAI: −0.62; A + J + P: −0.30; A + P: −0.68; A + J: −0.29; and J + P: −0.30). The oils and their formulations are a potential larvicidal source for mitigating the proliferation of diseases by this vector.

The mosquito Aedes aegypti is the vector responsible for the transmission of important arboviruses such as dengue fever, Chikungunya, Zika virus, and yellow fever. These diseases affect millions of people and exert impacts on healthcare systems throughout the world. Given the increasing resistance to synthetic insecticides, essential oils from plants constitute an ecologically viable alternative for the control of this vector. The aim of the present study was to investigate the larvicidal activity of the essential oil (EO), aqueous extract, rutin, and hydrolate from the leaves of Myrciaria floribunda against Aedes aegypti larvae in the initial L4 stage. The yield of EO was 0.47%. Thirty-seven chemical constituents were identified and quantified using chromatographic methods. The major constituents were (E)-caryophyllene (27.35%), 1,8-cineole (11.25%), β-selinene (4.92%), and α-muurolene (4.92%). In the larvicidal tests, the lethal concentration (LC₅₀) was 201.73 ppm for the essential oil, 15.85% for the aqueous extract, and 22.46 ppm for rutin. The hydrolate had no larvicidal activity. The compounds that exhibited larvicidal activity against Aedes aegypti constitute a promising option for the development of natural formulations to diminish the propagation of this vector.

New cancer therapies development is a huge demand. This research evaluated cytotoxic activity against normal and cancer cells of brown algae (Dictyotales) extracts with high antioxidant activity. Canistrocarpus cervicornis, Dictyopteris delicatula and Lobophora variegata extracts from two beaches of Pernambuco were obtained by two serial maceration method: 1° Extraction—dichloromethane and methanol (2:1 v/v) and subsequently water at 60 °C; 2° Extraction—dichloromethane and methanol (2:1 v/v), subsequently ethanol and finally water at 80 °C. Phenolic compounds and cytotoxicity against normal cell lines L-929 (murine fibroblast), PBMC (human peripheral blood mononuclear cells) and J774A1 (mouse macrophages), and cancer cell lines P815 (murine mastocytoma), S-180 (murine Sarcoma), NCI-H292 (human lung mucoepidermoid carcinoma), HCT-116 (human colorectal carcinoma), JUKART (human T cell leukaemia) and MCF-7 (human breast adenocarcinoma) were assessed. Only for L-929 strain, among normal cells, extracts presented cytotoxicity. Organic extracts showed moderate to high cytotoxic activity against P815, MCF-7 and HCT-116 cancer cell lines. Organic extract L. variegata Jaguaribe 2° Extraction exhibited the best cytotoxic activity with high IC₅₀ values (28–35 µg/mL). Thus, we evaluate its acids profile that showed important polyunsaturated fatty acids and carboxylic acid, such as arachidonic acid and cinnamic acid that is being reported to L. variegata for the first time. Various research demonstrated the anticancer activity of this substance. Therefore, the high cytotoxic activity of our most active extract could be due to the presence of fatty acids and carboxylic acid, acting synergically, including cinnamic acid. These results encourage macroalgae use as an anticancer metabolites source for human therapies.

RESUMONesse artigo procedemos a análise de uma Mostra de Ciências realizada em uma escola pública da cidade do Recife que utilizou o tema Ciência e Arte. A partir dessa interface e considerando as múltiplas potencialidades de feiras de conhecimento, buscamos identificar a partir dos trabalhos expostos, da percepção dos estudantes e da avaliação dos professores de ciências da natureza e do corpo gestor da escola quais competências propostas pela Base Nacional Comum Curricular foram atingidas com a Mostra. Diante da análise, identificamos trabalhos que desenvolveram diversas competências e alguns que não foram capazes de explorar toda sua potencialidade. Como avaliação geral da Mostra, tanto docentes quanto gestores avaliaram positivamente. Dessa forma, foi possível construir conhecimentos e competências além da inteligência lógicomatemática a partir da interface entre Ciência e Arte. Ciência e arte. Competências. Base Nacional Comum Curricular. The Chemistry and Art Interface in BNCC Skills Development ABSTRACT In this article we proceeded to the analysis of a Science Fair in a public school of Recife that used the theme Science and Art. From this interface and considering the multiple potentials of science fairs, we search to identify from the works exposed, the students' perception and the evaluation of the teachers of the natural sciences and the school management which competences proposed by the National Common Curriculum Base were reached with the Fair. With the analysis, we identified works that developed several competences and some that were not able to exploit their full potential. As a general evaluation of the Fair, both teachers and managers evaluated positively. Thus, it was possible to build knowledge and skills beyond logical-mathematical intelligence from the interface between Science and Art. Science and Art. Competences. National Common Curriculum Base.Tra la Chimica e l'Arte nel il sviluppo delle competenze de la Base del Curriculum Nazionale Brasiliano RIASSUNTO In questo articolo abbiamo proceduto all'analisi di una mostra di Scienza trascorsa in una scuola pubblica nella città di Recife, Brasile, che ha utilizzato il tema Science e Arte. Tra le molteplici potenzialità delle fiere della conoscenza, cerchiamo di identificare dall quello esposto, la percezione degli studenti e la valutazione degli insegnanti di scienze naturali e della gestione della scuola quali le competenze proposte dalla Base di Curriculum Nazionale Brasiliano erano state ragiunte. Da le l'analisi, abbiamo identificato lavori che hanno sviluppato diverse competenze e alcune che non sono stati in grado di sfruttare tutto il loro potenziale. Come valutazione generale della mostra, sia gli insegnanti che i dirigenti la hanno valutato positivamente. Quindi, è stato possibile costruire conoscenze e abilità oltre l'intelligenza logico-matematica dall'interfaccia tra Scienza e Arte. Scienza e Arte Abilità. Curriculum Nazionale Brasiliano. La interfaz química y artística en el desarrollo de habilidades BNCC RESUMEN En este artículo se procedió al análisis de una Feria de Ciencias en una escuela pública de Recife que utilizó el tema Ciencia y Arte. Desde esta interfaz y teniendo en cuenta los múltiples potenciales de las ferias de ciencias, buscamos identificar a partir de los trabajos expuestos, la percepción de los estudiantes y la evaluación de los profesores de ciencias naturales y la gestión escolar, las competencias propuestas por la National Common Curriculum Base. con la feria Con el análisis, identificamos trabajos que desarrollaron varias competencias y algunos que no pudieron explotar todo su potencial. Como una evaluación general de la Feria, tanto los maestros como los gerentes evaluaron positivamente. Por lo tanto, fue posible desarrollar conocimientos y habilidades más allá de la inteligencia lógicomatemática desde la interfaz entre Ciencia y Arte. Ciencia y arte. Competencias Base Nacional Curricular Común.

Myrciaria floribunda is a plant found in the Northeast region of Brazil with several insecticidal properties that remain little explored. In this sense, this study aims to investigate the harmful effects of essential oil (EO) from M. floribunda leaves against Sitophilus zeamais, an important corn pest. The EO was applied in toxicity tests by fumigation, contact, and ingestion, as well as in in vitro assays to evaluate its effects on the activity of the enzymes α-amylase, trypsin, and acetylcholinesterase. Chromatographic analysis of the oil revealed (E)-caryophyllene (56.41%), viridiflorol (4.02%) and α-selinene (3.85%) as the main compounds. The essential oil (EO) showed fumigation toxicity, with an LC₅₀ of 3.2 μL/L of air, and (E)-caryophyllene with an LC₅₀ of 3.97 μL/L of air. The EO inhibited insect feeding, altering growth rate and feed conversion efficiency starting at 62.5 μL/g. In this study, an increase in amylase and acetylcholinesterase (AChE) activity was observed. This increase in AChE activity may cause an imbalance in the nervous system, leading to insect death. Thus, the EO of M. floribunda may serve as an alternative for the control of S. zeamais in stored corn and help prevent significant post-harvest losses for farmers.