Interval-censored failure time data occur in many medical investigations as well as other studies such as demographical and sociological studies. They include the usual right-censored failure time data as a special case but provide much more complex structure and less relevant information than the right-censored data. This article reviews some basic concepts, issues and the corresponding statistical approaches related to the analysis of interval-censored data as well as recent advances. In particular, we discuss estimation of a survival function, comparison of several treatments and regression analysis as well as competing risks analysis and truncation in the presence of interval censoring. A well-known example of interval-censored data is described and analysed to illustrate some of the statistical procedures discussed.
The simultaneous estimation and variable selection for Cox model has been discussed by several authors when one observes right-censored failure time data. However, there does not seem to exist an established procedure for interval-censored data, a more general and complex type of failure time data, except two parametric procedures. To address this, we propose a broken adaptive ridge (BAR) regression procedure that combines the strengths of the quadratic regularization and the adaptive weighted bridge shrinkage. In particular, the method allows for the number of covariates to be diverging with the sample size. Under some weak regularity conditions, unlike most of the existing variable selection methods, we establish both the oracle property and the grouping effect of the proposed BAR procedure. An extensive simulation study is conducted and indicates that the proposed approach works well in practical situations and deals with the collinearity problem better than the other oracle-like methods. An application is also provided.