Radu Lăcătuș

Prof. Dr. Radu Lăcătuș


Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 December 2024 in Animals
Verified
Journal Article
Open access
PDF file
SMSorin Marian Mârza
Sorin Marian Mârza
Camelia MunteanuCamelia Munteanu
Camelia Munteanu
IPIonel Papuc
Ionel Papuc
RLRadu Lăcătuș
Radu Lăcătuș
PDPetraru Diana
Petraru Diana
RPRobert Purdoiu
Robert Purdoiu
Cortisol, an essential glucocorticoid hormone, is crucial in regulating the stress response and maintaining physiological and behavioral homeostasis in mammals, including dogs. This review explores cortisol’s physiological and behavioral role in canines, focusing on its effects on stress, immune function, and metabolism. Various methods of measuring cortisol levels in dogs, invasive (blood, saliva, urine) and non-invasive (hair, fecal assays), are discussed regarding their accuracy and practical applications. The review also highlights the influence of different environmental factors, such as shelter conditions, human interaction, and music, on cortisol levels in dogs. Furthermore, the clinical and behavioral implications of abnormal cortisol levels are examined, with particular attention to conditions like Cushing’s disease and stress-related behavioral issues. The findings emphasize the importance of cortisol monitoring in veterinary practice and animal welfare, proposing future research directions to improve canine health and stress management.

15 October 2025 in Animals
Verified
Journal Article
Open access
PDF file
SMSorin Marian Mârza
Sorin Marian Mârza
Camelia MunteanuCamelia Munteanu
Camelia Munteanu
IPIonel Papuc
Ionel Papuc
RLRadu Lăcătuș
Radu Lăcătuș
RPRobert Purdoiu
Robert Purdoiu
This review examines the diverse ways in which probiotics, defined as live microorganisms that provide health benefits to the host when administered in adequate amounts, contribute to animal health and welfare across both livestock and companion species. By modulating gut microbiota, enhancing immune responses, and suppressing harmful pathogens, probiotics represent an effective strategy for disease prevention and performance improvement without reliance on antibiotics. In livestock production, these beneficial microbes have been shown to optimize feed utilization, support growth, and reduce methane emissions, thereby contributing to more sustainable farming practices. Their role extends beyond productivity, as probiotics also help mitigate antimicrobial resistance (AMR) by offering natural alternatives to conventional treatments. In aquaculture, they further promote environmental sustainability by improving water quality and reducing pathogen loads. For companion animals such as dogs and cats, probiotics are increasingly recognized for their ability to support gastrointestinal balance, alleviate stress through gut–brain axis interactions, and aid in the management of common conditions including diarrhea, food sensitivities, and allergies. The integration of probiotics into veterinary practice thus reflects a growing emphasis on holistic and preventive approaches to animal health. Despite these advances, several challenges remain, including variability in strain-specific efficacy, regulatory limitations, and cost-effectiveness in large-scale applications. Emerging research into precision probiotics, host–microbiome interactions, and innovative delivery methods offers promising avenues to overcome these barriers. As such, probiotics can be regarded not only as functional supplements but also as transformative tools that intersect animal health, productivity, and sustainability.

9 October 2021 in Materials
Verified
Journal Article
Open access
PDF file
Mariana Domnica StanciuMariana Domnica Stanciu
Mariana Domnica Stanciu
MMMircea Mihălcică
Mircea Mihălcică
FDFLORIN DINULICA
FLORIN DINULICA
ANAlina Maria Nauncef
Alina Maria Nauncef
RPRobert Purdoiu
Robert Purdoiu
GGGhiorghe Vasile Gliga
Ghiorghe Vasile Gliga
Numerous studies on heritage violins have shown that there are a number of factors that contribute to the acoustic quality of old violins. Among them are the geometric shape of the violin, the thickness of the tiles, the arching of the tiles, the dimensions and position of the bass bar, the size and position of the acoustic holes. Thus, the paper aims to compare the structural and constructive elements of old violins made in various famous violin workshops (Stainer, Klotz, Leeb, Babos Bela), using nondestructive and noncontact techniques based on image analysis. The violins that were studied date from 1716 to 1920, being in good condition, most of them being used by artists from the Brașov Philharmonic of Romania. In the first stage of the study, the violins were optically analyzed and scanned to identify the structure of the resonant wood, using the WinDENDRO Density 2007 program. X-ray imaging and computed tomography (CT) were also used. Combining the types of analyses, capitalizing on the expertise of violin producers and the knowledge of researchers in the field, valuable data on the geometric and constructive characteristics of old violins were extracted.

16 October 2024 in Toxics
Verified
Journal Article
Open access
PDF file
FFFlorin-Ioan Fechete
Florin-Ioan Fechete
MPMaria Popescu
Maria Popescu
SMSorin Marian Mârza
Sorin Marian Mârza
LOLoredana Elena Olar
Loredana Elena Olar
IPIonel Papuc
Ionel Papuc
BDBora Florin Dumitru
Bora Florin Dumitru
Heavy metal contamination in agricultural soils presents serious environmental and health risks. This study assessed the bioaccumulation and spatial distribution of nickel, cadmium, zinc, lead, and copper within a sheep-based food chain in the Baia Mare region, Romania, which includes soil, green grass, sheep serum, and dairy products. Using inductively coupled plasma mass spectrometry (ICP-MS), we analyzed the concentrations of these metals and calculated bioconcentration factors (BCFs) to evaluate their transfer through trophic levels. Spatial analysis revealed that copper (up to 2528.20 mg/kg) and zinc (up to 1821.40 mg/kg) exceeded permissible limits, particularly near former mining sites. Elevated lead (807.59 mg/kg) and cadmium (2.94 mg/kg) were observed in industrial areas, while nickel and cobalt showed lower concentrations, but with localized peaks. Zinc was the most abundant metal in grass, while cadmium transferred efficiently to milk and cheese, raising potential health concerns. The results underscore the complex interplay between soil properties, contamination sources, and biological processes in heavy metal accumulation. These findings highlight the importance of continuous monitoring, risk assessment, and mitigation strategies to protect public health from potential exposure through contaminated dairy products.

5 September 2024 in Life
Verified
Journal Article
Open access
PDF file
LOLoredana Elena Olar
Loredana Elena Olar
VTVasile-Daniel Tomoiaga
Vasile-Daniel Tomoiaga
SMSorin Marian Mârza
Sorin Marian Mârza
IPIonel Papuc
Ionel Papuc
IBIoan Florin Beteg
Ioan Florin Beteg
RLRadu Lăcătuș
Radu Lăcătuș
Coenurosis is a parasitic disease caused by the larval stage of Taenia multiceps, Coenurus cerebralis, typically found in the central nervous system of different livestock such as sheep and goats. The blood plasma from fifteen clinically healthy sheep and six sheep with neurological symptoms was studied by fluorescence spectroscopy in order to establish the contribution of kynurenic acid (KYNA), the neuroprotective metabolite of the kynurenine pathway, to the total fluorescence of the plasma. CT scans were used to confirm the presence of cysts in the central nervous system of sheep with neurological symptoms. The fluorescence spectroscopy analysis and further spectra deconvolution process revealed some significantly lower KYNA contributions to the total plasma fluorescence in sheep with coenurosis compared to healthy controls. Our results indicate that KYNA emission parameters could serve as valuable diagnostic markers, particularly for detecting preclinical cases of coenurosis, thus allowing for improved farm management practices.

8 April 2026 in Life
Verified
Journal Article
Open access
PDF file
SMSorin Marian Mârza
Sorin Marian Mârza
Camelia MunteanuCamelia Munteanu
Camelia Munteanu
RLRadu Lăcătuș
Radu Lăcătuș
IPIonel Papuc
Ionel Papuc
BDBora Florin Dumitru
Bora Florin Dumitru
RPRobert Purdoiu
Robert Purdoiu
Ionizing radiation therapy has undergone a clear paradigm shift in veterinary oncology and inflammatory disease management, moving from mainly palliative use toward structured, curative treatment programs. This review synthesizes current evidence on key modalities used in veterinary practice, including external beam radiotherapy, brachytherapy, systemic targeted radionuclide therapy, stereotactic radiosurgery, stereotactic body radiotherapy, radiosynoviorthesis, and low-dose radiotherapy. Each modality is discussed in relation to its physical and biological basis, major isotopes or beam types, routes of delivery, target species such as dogs, cats, and horses, clinical indications, and global availability. Comparative analysis highlights differences in clinical acceptance, evidence strength, access, and cost. External beam radiotherapy and stereotactic techniques support curative tumor management, whereas radiosynoviorthesis and low-dose radiotherapy are effective for inflammatory and degenerative disorders. Despite ongoing progress, challenges remain in access, dosimetry standardization, and prospective evidence. Companion animals are also emphasized as valuable translational models, guiding future innovation and collaboration internationally.